Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies by Mansour Haidar (6255134)

DataSheet_1_Cardiovascular risk factors: The effects of ageing and smoking on the immune system, an observational clinical study.docx by H. W. Grievink (13796470)

Glatiramer Acetate (Copaxone) Modulates Platelet Activation and Inhibits Thrombin-Induced Calcium Influx: Possible Role of Copaxone in Targeting Platelets during Autoimmune Neuroin... by Sarah C. Starossom (345655)

“…We found that GA inhibited thrombin-induced calcium influx in human and mouse platelets. GA also decreased thrombin-induced CD31, CD62P, CD63, and active form of αIIbβ3 integrin surface expression and formation of platelet aggregates for both mouse and human platelets, and prolonged the bleeding time in mice by 2.7-fold. …”

DataSheet2_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.ZIP by Qianqian Huang (1409008)

“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”

DataSheet1_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.PDF by Qianqian Huang (1409008)

“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”

DataSheet3_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.ZIP by Qianqian Huang (1409008)

“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”

Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins by Chunxiang Yao (834346)

“…Catalase overexpression globally decreased thiol occupancy by ≥1.3 fold in 82 proteins, including numerous mitochondrial and contractile proteins. …”

DataSheet1_Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase.PDF by Lijun Ma (207865)

“…However, the spleen index decreased in the OXA and LBP + OXA groups (p < 0.05), possibly as a side effect of oxaliplatin. …”

Biochemical protease interactions represented by graph theory. by Nikolaus Fortelny (568773)

“…(v) If a protease inhibitor is present, the protease does not cleave substrates. …”

Pi transporters in human valve interstitial cells (VICs). by Diala El Husseini (290642)

“…</b> Following exposure to Pi, VICs have increased expression of SLC20A1 and SLC20A2 transcripts by several folds, with the highest magnitude for SLC20A1 (results expressed in function of SLC20A2 as the referent) (SLC20A1 increased by 5.3-folds when compared to SLC20A2) <b>C</b>. …”

Involvement of SKN-1 in immunosenescence. by Diána Papp (169090)

“…<p>(<b>A</b>) Representative epifluorescence images showing the decreased induction of the <i>gcs-1</i> promoter. …”

Flight Scheduling in the Airspace by Msakni, Mohamed Kais

“…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. The tests were conducted under a Windows 7 machine with an Intel Core i7 and 8 GB of RAM. …”
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File S1 - Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor by Carola E. Bunse (492512)

“…After 48 h of storage at 4°C, a mean of 93% (mCMV_pp65_A02, n = 4) and 96% (mCMV_pp65_B07, n = 5) of the frequency in the fresh sample (baseline) was obtained. …”

FOXM1 directly binds to and induces transcriptional activity of <i>Dusp1</i> promoter in macrophages. by Chinmayee Goda (8694597)

“…<p><b>(A)</b> Depletion of <i>Foxm1</i> in macrophages decreased <i>Dusp1</i> mRNA and increased <i>Tnf</i>, <i>Il6</i> and <i>Il1b</i> mRNA. …”

Hierarchical clustering analysis of the expression of 390 miRNAs obtained from whole embryos of E9 by Junichi Mineno (15939)

“…All rights reserved</p>5, E10.5 and E11.5. () Heatmap and dendrogram (a tree graph). …”

Biological experiments using human CRC cell lines show feedback regulation of progenitor NECs occurs via mature GLP-2R+ and SSTR1+ NECs. by Tao Zhang (43681)

“…To investigate paracrine signaling influence of NECs on ALDH+ cells, we studied the effect of CM from GLP-2R+ or from SSTR1+ cells on ALDEFLOUR+ cells isolated from the HT29 cell line. There was a significant decrease in the number of ALDEFLOUR+ cells grown in GLP-2R+ CM, but not SSTR1+ CM. …”

Unexpected Selectivities in C−H Activations of Toluene and <i>p</i>-Xylene at Cationic Platinum(II) Diimine Complexes. New Mechanistic Insight into Product-Determining Factors by Lars Johansson (219399)

“…The elimination of toluene from (N^fN^f)Pt(Tol)₂ species (<b>3a</b>−<b>c</b>; <b>a</b>, Tol = <i>o</i>-tolyl; <b>b</b>, Tol = <i>m</i>-tolyl;<b> c</b>, Tol = <i>p</i>-tolyl) after protonolysis with 1 equiv of HBF₄ was investigated. …”

Long-term cultivation of MSCs alters their mitochondrial function. by Sven Geißler (108595)

“…(<b>C</b>): The total antioxidant capacity decreases with increasing passage number. Moreover, yMSCs of P2 and P100 exhibited significant higher antioxidant activities than aMSCs of the same passage. …”

Long term PFC accumulation and correlation to viral tumor load. by Stephanie Weibel (127241)

“…(<b>D</b>) quantitative evaluation of the ¹⁹FTVR decrease (7 to 11 dpi) of mock-infected and GLV-1h68-treated 1936-MEL tumors during the time course study measured by <i>in vivo </i>¹⁹F MRI revealed a significant difference between both groups (n = 4; p = 0.038). …”

Triterpene acid- and lectin-containing extracts induce apoptosis in leukaemia cells. by Catharina I. Delebinski (780210)

“…<p><b>A.</b> To measure the induction of apoptosis by VAE, U937 and HL-60 cells were treated with different concentrations of the extracts for 18 h. …”