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741
Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage
Published 2013“…Contactin 5 (CNTN5) has also been implicated in the development of AD by a genome-wide association study. …”
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742
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744
Rdh10a deficient embryos have decreased expression of RA signaling responsive genes.
Published 2015“…<p>(A-F) ISH for <i>cyp26a1</i>, <i>hoxb5b</i>, <i>and dhrs3a</i> expression in control sibling and Rdh10a deficient embryos. …”
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745
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746
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747
a-c: Bone marrow (BM) HIF2 α is inappropriately decreased in uremic anemia.
Published 2018“…<p>BM HIF2 α protein (depicted as percentage of actin-corrected concentration) increases in 7 day-bled rats (Fig 2a) Vs control. Contrary to that, BM HIF2 α protein decreases in uremic (4 weeks after 5/6 nephrectomy) rats (Fig. 2b). …”
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748
<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets.
Published 2017“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”
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749
Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2
Published 2011“…(A), data are given as fold change in cathepsin K mRNA of bleomycin-challenged cath K tg mice compared to wild-type mice. …”
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750
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756
Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
Published 2013“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”
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757
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758
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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759
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
Get full text
Get full text
Get full text
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