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Presentation 1_Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete a diffusible mitogenic factor.pdf
Published 2025“…Live-cell imaging growth analyses again showed increased growth in A7r5 cells transfected with p.Tyr955Cys but a decreased growth with p.Arg1138Cys, while p.Tyr955Cys increased growth of HeLa cells. …”
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Representative fluorescent records of IntegriSense 680<sup>®</sup> dye-labeled αvβ3 integrin in control and cetrorelix-treated non-pregnant rats.
Published 2024“…Cetrorelix treatment reduced αvβ3 integrin expression, which caused a significant decrease in intensity (bottom image row). …”
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949
Administration of APB5, but not APA5, decreases the hyperplasia of alveolar type 2 epithelial cells induced by BLM.
Published 2018“…The administration of APB5 markedly decreased the hyperplasia of type 2 epithelial cells induced by BLM. …”
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Attenuation of spheroid size decrease or MUC5AC increase by hit compounds.
Published 2023“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”
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955
Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain.
Published 2014“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”
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Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice.
Published 2022“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”
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