Supplementary Material for: Vitamin D₃ Treatment Decreases Frequencies of CD16-Positive and TNF-α-Secreting Monocytes in Asthmatic Patients by Grubczak K. (4152079)

“…Interestingly, we found that a combined treatment of 1,25-(OH)₂D₃ and GC allowed for a 5-fold reduction of the GC dose while maintaining their anti-inflammatory effects. …”

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment by Denise K. Schach (1522021)

“…Below pH 6, the sequence folds into a helix and can disrupt membranes. In this study, we show that the lipid bilayer radius-of-curvature has a negligible effect on GALA-induced leakage kinetics and that GALA remains pH responsive after inserting into a lipid membrane. …”

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment by Denise K. Schach (1522021)

“…Below pH 6, the sequence folds into a helix and can disrupt membranes. In this study, we show that the lipid bilayer radius-of-curvature has a negligible effect on GALA-induced leakage kinetics and that GALA remains pH responsive after inserting into a lipid membrane. …”

A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…DNA-sequencing detected a 12-nucleotide long thymidine (12T) insertion(ins)/deletion(del) polymorphism within a poly-T sequence (38T vs 26T) in the <i>ATP1A1</i> 5’-regulatory region associated with hypertension in a male Sardinian population. …”

Variability of biological measures decreases with increasing biological complexity. by Meghan L. M. Fuzzen (3239400)

Cumulative effects and geographic distribution of mCHG-decreasing alleles. by Eriko Sasaki (501178)

“…Filled circles indicate mCHH- or mCHG-decreasing alleles. Mapping and statistical testing were performed in R version 3.5.3. …”

Longer polyQ sequences decrease the transcriptional activity of AR. by Carlos M. Roggero (11909585)

δPKC activation following OGD decreases Bad phosphorylation via PP2A activation. by Kunjan R. Dave (348112)

HuR knockdown moderately decreases p53 expression in MCF10A cells. by Wensheng Yan (307121)

Fig 5 - by Zhe Xu (127066)

Subjects:

Prorocentin-5: A Cytotoxic Polyketide from the Benthic Marine Dinoflagellate <i>Prorocentrum lima</i> by Yunseok Choi (5625245)

Subjects:

RMSD graphs for the backbone of WT PARG1, I845V and T622M mutants. by Zen Kouchi (14898435)

Decreased pulmonary cell inflammatory response in FI-A2 and G-A2 peptide vaccinated mice after RSV challenge. by Gertrud U. Rey (501694)

Plasma IL-6 in PASC is higher than RC and correlates with frequency of SARS-CoV-2-specific TNF-α producing CD8⁺ T cells. by Katherine M. Littlefield (12647420)

HERVK HML-2 <i>env</i> knockdown decreases IFN-I expression and alters the secretory profile of THP1 monocytes and primary MDMs. by Natallia Mikhalkevich (10113822)

“…<p>(<b>A</b>) Transcription of HERVK HML-2 and five other HERV clades, identified upregulated by RNA-Seq in both irradiated THP1 cells and MDMs (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1009305#ppat.1009305.g004" target="_blank">Fig 4A</a>), measured by RT-qPCR in THP1 cells expressing control (grey) or shRNA-Env (red), 48h post-irradiation. …”

A Y45F mutation in hepatitis C virus NS4A causes a decrease in infectious viral titer. by Allison E. Roder (6312761)

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

“…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”

Comparison of the decrease of CFU in CSF and blood between treatment groups within the first 6 h after treatment. by Luca G. Valente (12463057)

Fig 5 - by Thiago Bezerra Wanderley e Lima (14232350)

Reduced expression of Tks5 leads to decreased growth of tumor cells <i>in vitro</i> and <i>in vivo</i>. by Barbara Blouw (715467)