Discovery and Development of <i>N</i>‑[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Act... by Ramakrishna Nirogi (2025910)

“…A series of chemical optimizations guided by in vitro affinity at a histamine H₃ receptor (H₃R), physicochemical properties, and pharmacokinetics in rats resulted in identification of <i>N</i>-[4-(1-cyclobutyl-piperidin-4-yloxy)­phenyl]-2-(morpholin-4-yl)­acetamide dihydrochloride (<b>17v</b>, SUVN-G3031) as a clinical candidate. …”

Intermolecular Hydrogen-Bond Networks and Physical Properties of BF₄^– and TCNQ^{<b>•</b>–} Salts of Three-Fold Symmetric Tris(alkylamino)phenalenylium... by Tsuyoshi Murata (1939669)

“…In the crystal structures of the BF₄^– salts, the TAP skeleton possesses a nearly 3-fold symmetric molecular plane indicating the delocalization of positive charge. …”

Each types of tuberculosis ASMR in 1990 and 2021. by Xue Li (285380)

“…The age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR) of TB in females decreased faster than males. The incidence was higher in children under 5 years old and adolescents aged 15 to 19, showing a bimodal pattern. …”

Each types of tuberculosis ASDR in 1990 and 2021. by Xue Li (285380)

“…The age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR) of TB in females decreased faster than males. The incidence was higher in children under 5 years old and adolescents aged 15 to 19, showing a bimodal pattern. …”

Each types of tuberculosis ASIR in 1990 and 2021. by Xue Li (285380)

“…The age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR) of TB in females decreased faster than males. The incidence was higher in children under 5 years old and adolescents aged 15 to 19, showing a bimodal pattern. …”

The incidence, death and DALYs in individuals aged 0 to 19 years in 204 countries and territories in 2021. by Xue Li (285380)

ASDR of Tuberculosis for the 21 Global Burden of Disease regions by SDI, 1990-2021. by Xue Li (285380)

Temporal trends of tuberculosis ASIR by Xue Li (285380)

Age standardized incidence rates of Tuberculosis for the 21 Global Burden of Disease regions by SDI, 1990-2021. by Xue Li (285380)

ASMR of Tuberculosis for the 21 Global Burden of Disease regions by SDI, 1990-2021. by Xue Li (285380)

Incidence, death and DALYs of TB, by age and sex in 2021. by Xue Li (285380)

Fig 1 - by Denise Wajnsztajn (3366902)

Gene expression analyses of Cluster 6. by Jillian A. Bristol (5566289)

Both T1 and T2 LCLs can be separated into 11 separate clusters in scRNA-seq analysis. by Jillian A. Bristol (5566289)

DataSheet_5_Agouti overexpression in a transgenic model regulates integrity, permeability and electrogenic amino acid transport in zebrafish intestine.pdf by Esther Leal (415661)

Fig 3 - by Hiroshi Kataoka (270804)

“…Adding the Max GD improved the model’s short-term renal prognostic ability to about 1.5-fold for patients with IgAN 4 years after kidney biopsy, and the model’s long-term renal prognostic ability to more than 3-fold for patients with IgAN at the end of the study. …”

Fig 4 - by Denise Wajnsztajn (3366902)

Image_2_The Recombinant Eg.P29-Mediated miR-126a-5p Promotes the Differentiation of Mouse Naive CD4+ T Cells via DLK1-Mediated Notch1 Signal Pathway.tif by Xiancai Du (10970190)

“…One week after P29 immunization of mice, we found that miR-126a-5p was significantly increased and DLK1 expression was decreased, while Notch1 pathway activation was enhanced and Th1 response was significantly stronger. …”

Image_1_The Recombinant Eg.P29-Mediated miR-126a-5p Promotes the Differentiation of Mouse Naive CD4+ T Cells via DLK1-Mediated Notch1 Signal Pathway.tif by Xiancai Du (10970190)

“…One week after P29 immunization of mice, we found that miR-126a-5p was significantly increased and DLK1 expression was decreased, while Notch1 pathway activation was enhanced and Th1 response was significantly stronger. …”

Spreadsheet for segmentation data. by Renxin Chu (5169857)