<i>Prss21</i>^<i>-/-</i> mice display increased vascular permeability during luteal angiogenesis and decreased endothelial VE-cadherin expression. by Raymond J. Peroutka (8946971)

Paired t test for the (A) Slow-4 and (B) Slow-5 frequency band, <i>p</i> < 0.05, AlphaSim corrected. by Lei Gao (6566)

<b>Data and R Code for Reproducibility of </b><i>"Forest productivity decreases in response to recent changes in vegetation structure and climate in the latitudinal extremes of the... by Julián Tijerín-Triviño (20377161)

SAHA treatment decreases HDAC2 protein levels but does not affect the protein levels of other class I and IIa HDACs – 2^nd trial. by Michal Mielcarek (195209)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Table_5_Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.XLSX by Dominik Modrzejewski (5639621)

“…In addition, we ran a binary logistic regression analysis to verify five factors that may affect the occurrence of off-target effects: (1) Number of mismatches (2) Position of mismatches (3) GC-content of the targeting sequence (4) Altered nuclease variants (5) Delivery methods. …”

Image_5_Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs.PDF by Qinglei Xu (8497341)

“…A total of 400 weaned pigs [Duroc × (Landrace × Yorkshire)] were randomly allocated into one of four treatments: the CON group, fed with basic diet; the HM1 group, fed with basal diet supplemented with 0.5 g herbal mixture/kg diet; the HM2 group, fed with basal diet supplemented with 1.0 g herbal mixture/kg diet; or the HM3 group, fed with basal diet supplemented with 1.5 g herbal mixture/kg diet. …”

Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor by Shruti Lal (16805936)

“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”

<i>Trem1^−/−</i> mice develop smaller inflammatory lesions and show decreased cellular infiltrates at <i>L. major</i> infection sites. by Benjamin Weber (509906)

Decreased NK1.1^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Underlying data for Figs 6, S5, and S6. by Kun Wu (286745)

Flow chart. by Raphaele Houlbracq (20558509)

“…The difference in overall prevalence of OASI between 2010 (0.7%) and 2021 (1.0%) was not statistically significant after adjustment (aRR 1.24, 95% CI 0.91 to 1.68). By groups of classification, the prevalence of OASI increased significantly only in Group 2b [nulliparous term cephalic singleton with spatula delivery] from 2.6% (95% CI 1.2 to 5.6) in 2010 to 9.6% (95% CI 6.2 to 14.7) in 2021 (aRR 3.69, 95% CI 1.50 to 9.09), and did not differ statistically significantly in Group 2a [nulliparous term cephalic singleton with forceps delivery] from 3.2% (95% CI 1.8 to 5.7) in 2010 to 5.7% (95% CI 3.4 to 9.5) in 2021 (aRR 1.78, 95% CI 0.81 to 3.90).…”

Image_5_GPR174 mRNA Acts as a Novel Prognostic Biomarker for Patients With Sepsis via Regulating the Inflammatory Response.tif by Jianli Wang (1305390)

Image 5_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

Data_Sheet_1_Mental health across two years of the COVID-19 pandemic: a 5-wave longitudinal study in Germany.PDF by Maxi Weber (12420430)

Table 5_Dynamic proteomics reveals that endosperm weakening plays a critical role during seed germination in Polygonatum cyrtonema Hua.xlsx by Huilong Xu (1358961)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin by Stephanie A. Eytcheson (4284421)

“…Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. …”

PEDV and PDCoV infection impairs the cilium. by Tenghan Zhuang (22238809)

“…Notably, infection by either porcine epidemic diarrhea virus (PEDV) or porcine deltacoronavirus (PDCoV) resulted in a significant decrease in both the percentage of cells with cilium and the average ciliary length across all three porcine cell lines (<i>C-D, F-G, and I-J</i>). …”

Video_5_Programmable Attenuation of Antigenic Sensitivity for a Nanobody-Based EGFR Chimeric Antigen Receptor Through Hinge Domain Truncation.avi by Scott McComb (234597)