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15761
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15762
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15763
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Published 2019“…The long-term antidiabetic efficacies of <b>5</b> (10 mg/kg, qw) were better than those of the once-weekly trelagliptin and omarigliptin, especially in decreasing the hemoglobin A1c level.…”
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15764
Table 5_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx
Published 2025“…Background<p>IGFBP5 is a differentially expressed gene (DEG) between M1 and M2 macrophages. …”
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15765
Image_5_Autophagy Induced Accumulation of Lipids in pgrl1 and pgr5 of Chlamydomonas reinhardtii Under High Light.TIF
Published 2022“…<p>Chlamydomonas (C.) reinhardtii is a potential microalga for lipid production. Autophagy-triggered lipid metabolism in microalgae has not being studied so far from a mutant of proton gradient regulation 1 like (PGRL1) and proton gradient regulation 5 (PGR5). …”
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15766
Table_1_Investigating the Added Value of the EQ-5D-5L With Two Bolt-On Items in Patients With Hemophilia.DOCX
Published 2021“…Spearman's rank correlation (rho) was used to assess the associations of the EQ-5D-5L and two bolt-on items with the Hemophilia Quality of Life Questionnaire for Adults (Haem-A-QoL) and SF-12. …”
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15767
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15768
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15769
Presentation_1_Risk of severe COVID-19 infection in persons with diabetes during the first and second waves in Denmark: A nationwide cohort study.pdf
Published 2022“…However, when mortality was restricted to the hospitalized population, the crude mortality fell from 26.8% to 19.6% in persons with diabetes, while only a minor decrease was seen in persons without diabetes (from 16.7% to 15.5%).…”
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15770
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15771
ERK5-RNA interference suppresses MCF-7-MEK5 tumor growth and restores ER-α protein expression.
Published 2013“…Decreased expression of ERK5 was confirmed with (A) RT-PCR and (B) western blot analysis. …”
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15772
Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5).
Published 2025“…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …”
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15773
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15774
Five years comparation of efficacy and safety after ICL-V4c implantation for high and super high myopia correction
Published 2024“…No significant difference of ECD was found in the high (2823.45 ± 274.75 cells/mm<sup>2</sup>) and super-high myopia (2856.71 ± 323.53cells/mm<sup>2</sup>) at the visit of 5 years. Compared to baseline, we observed a significant increase in IOP at the 1-week follow-up, which decreased significantly at the one-month visit. …”
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15775
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15776
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15777
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15778
αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
Published 2015“…To elucidate the mechanism, siRNAs against β5 integrin, CD36, Mer tyrosine kinase (MerTK), and Atg5, blocking antibodies against CD36 and MerTK, and a specific inhibitor for focal adhesion kinase (FAK) were used. …”
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15779
Cas4 family proteins are 5′-3′ exonucleases.
Published 2013“…Sso0001 (0.3 µM) was incubated with 3′ end labelled DNA 50mer (500 nM) in reaction buffer at 55°C and products were analysed at 1, 2, 3, 5 and 10 min. In a parallel reaction (lanes 6–10), a 20 fold excess (10 µM) of unlabeled oligonucleotide of the same sequence was added to the reaction at the 1 min time point. …”
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15780