CysC induces autophagy via the mTOR signaling pathway in either serum-containing or serum-free medium. by Belen Tizon (366124)

“…</b> The intensity of the bands was measured, and p-P70S6 protein levels were calculated relative to total P70S6 values showing a decrease in the level of P70S6 kinase phosphorylation. …”

The effect of abieslactone on the cell cycle and the expression of cell cycle regulators in HepG2 and SMMC7721 cells. by Guo-Wei Wang (673106)

“…<p>(A) Abieslactone treatment induced a dose dependent increase in the proportion of cells in the G₁ phase and a decrease in cells in the S and G₂ phases compared to the untreated control. …”

Short-term thalidomide has little effects on AD-like pathology and BACE1 regulation. by Ping He (33281)

“…Images showed that there is not obvious decrease in the number of activated CD45⁺ microglia (<b>A</b>) and GFAP⁺ astrocytes (<b>B</b>) around plaques in the neocortex (confirmed by Congo Red). …”

Emergence Trajectory 2, SWA→NSWA, continuous progression. by Divya Chander (635948)

“…This patient started in a slow-wave state (SWA). Over approximately 1.5 minutes, the patient transitioned into a state characterized by higher spindle power (sdSWA), and then showed a progressive decrease in delta and spindle power towards the NSWA region over about 20 minutes before waking. …”

Mathematical parameters describing the functional interactions among various cell types. by Ishwar K. Puri (358815)

“…Positive S(N_j) imply that a rate contributes to an increase in N_j while a negative value entails a corresponding population decrease.…”

Probing possible topologies of membrane tension-based inhibition of actin network assembly. by Alba Diz-Muñoz (236517)

“…Model I: WAVE2 complex dynamics in the absence of tension-mediated inhibition of actin polymerization (see also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002474#pbio.1002474.s006" target="_blank">S5B Fig</a> for early time points). …”

RTX treatment reduces bacterial burden in the infected eyes. by Tiffany Lin (3388415)

“…The RTX treatment caused a mild, but significant decrease of blinking reflexes (asterisk, p = 0.003, Two-way ANOVA) that was observed only a week post-treatment, followed by complete recovery. …”

Application of t-RNN to investigate changes in random and directed exploration [22]. by Yoav Ger (17486672)

“…The subject consecutively chooses the higher value action and suddenly switches and chooses the lower value action (denoted with a downward arrow). The bottom panel depicts t-RNN <i>β</i> random exploration parameter estimation, where it estimates a step decrease in the parameter after the ungreedy action selection. …”

Mouse phrenic nerve hemi diaphragm and bladder strip <i>ex vivo</i> assays. by Mark Elliott (33144)

“…Data were normalised to the contractile strength prior to toxin addition and fitted to a four-parameter equation. The time required to decrease the contractile strength by 50% (t₅₀) was determined from the fitted curves. …”

Ionosonde spread F and GPS L-band scintillation occurrence during moderate geomagnetic storms near the southern crest of the EIA in Argentina by Gilda González (9246194)

“…Additionally, wave-like oscillations of TEC are observed at ~4 – 7 LT on November 8, with a dominant period of ~40 minutes. Regarding the scintillation activity, S4 is higher than 0.5 on November 8 at about 5 – 7 LT. …”

Clamgulchian (Miocene–Pliocene) pollen assemblages of the Kenai Lowland, Alaska, and the persistence of the family Podocarpaceae by Linda M. Reinink-Smith (4164925)

“…These herb groups show increasing diversity near the top of the Neogene in the Alaskan flora. With a decrease in thermophiles, the Clamgulchian taxa show a transition towards a cooler climate. …”

Group differences in the time course of Blood Oxygen Level-Dependent (BOLD) responses over the entire course of the pain experience. by Imanuel Lerman (6331049)

“…Treatment with nVNS significantly decreased the response of the postcentral gyrus during and after the application of noxious thermal stimuli (5 seconds each), up to 12 seconds after cessation of the painful stimulus. …”

HSE might block the metastasis of breast cancer to lungs in animal model. by Jin Hee Park (153335)

“…Asterisks indicate a statistically significant decrease by t-test (***p<0.001). …”

The relative contribution of TAK1 and MAPK pathways in fibronectin DAMP induced expression of pro-inflammatory genes. by Pranav Maddali (15910220)

“…Fold regulation of gene expression for each cell line was determined using RT-PCR and a list of genes with ≥5-fold decrease in expression compared to control treated cells were generated. …”

Supplementary Material for: Critical evaluation of Pap test adherence to routine screening in Amazonas State, Brazil by deOliveira R.L. (20535881)

Should I stay, or should I go: Modeling optimal flight initiation distance in nesting birds by Liam Dowling (6009728)

“…In a complementary approach with specified parameters based on biologically-informed factors that likely influence a predator-prey encounter, we find that increasing the current reproductive value, concealment of the nest, or costs of lost parental care decrease optimal FID and can lead to the parent staying at the nest. …”

Enhanced regularity of spontaneous oscillations. by Tracy-Ying Zhang (822536)

“…ΔQ, defined as Q_synchronized-Q_{unsynchronized}, is measured for each bundle. Each color represents a synchronized group (5 groups total), and each point represents a bundle in the group. …”

Dynamic thrombin generation during the course of pregnancy. by Jonathan H. Foley (277140)

“…<p>Thrombin generating capacity was determined empirically using a thrombin generation assay. Each point (circle) in the figure is representative of a single individual's thrombin generating capacity. …”

Analyzing the Percentage of CTCF Compared to Total CTCF and BORIS Transcript. by Brent Schultz (817841)

“…(B) CSUM of %CTCF demonstrates statistically significant variation about the mean of %CTCF according to age. For a full explanation of the CSUM data and commensurate change point analysis, please see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113168#pone.0113168.s002" target="_blank">S2 Supplementary Information</a> and the online reference in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113168#sec002" target="_blank">methods</a> section.…”

Table_1_Mechano-Regulation of Trabecular Bone Adaptation Is Controlled by the Local in vivo Environment and Logarithmically Dependent on Loading Frequency.DOCX by Ariane C. Scheuren (9411685)

“…Cyclic loading induced positive net (re)modeling rates when compared to sham and static loading, mainly due to an increase in mineralizing surface and a decrease in eroded surface. Consequently, bone volume fraction increased over time in 2, 5, and 10 Hz (+15%, +21% and +24%, p ≤ 0.0001), while static loading led to a decrease in bone volume fraction (−9%, p ≤ 0.001). …”