Effect of signaling pathway inhibitors on ox-LDL-induced Klotho downregulation in proximal tubular cells. by Cristina Sastre (503532)

“…<p>Pretreatment of MCT with parthenolide (1 µM) or PD098059 (50 µM) for 1 hour attenuates the decrease in Klotho mRNA (<b>A</b>) and protein (<b>B</b>) induced by ox-LDL (25 µg/mL). …”

rAd-p53 induced apoptosis was reverted by Fbxw7-specific siRNA. by Kangsheng Tu (428934)

“…C) The percentage of apoptotic Hep3B cells infected with rAd-p53 was decreased by Fbxw7-specific siRNA. Values are mean±standard error, n=3. * <i>P</i><0.05 <i>vs</i> control; ** <i>P</i><0.05 <i>vs</i> Fbxw7 siRNA; *** <i>P</i><0.05 <i>vs</i> rAd-p53.…”

Impaired myogenic differentiation in myotubes from SMA patients. by Nicole Hellbach (5562965)

“…<p>Representative fluorescence microscopy showing myotubes stained for MYOG, MYH1E and TNNT as well as cell nuclei (Hoechst) and quantification of the positively stained cells showing significant decrease of the later developmental markers in SMA Type 1 cells (A). …”

BV modulates GSK3β-mediated suppression of Foxp3⁺ Treg cells <i>in vitro</i>. by Ran Fu (434520)

“…<p>(A), Representative flow cytometric results of Foxp³⁺ Treg cells in cultured splenocytes after incubation with BV or transfection with GSK3β siRNA for 72 h. …”

Dramatic reduction of Dystrophin Dp71 expression in detached retina. by Abdoulaye Sene (258556)

“…<p>A: Western blot analysis of Dp71 and β-Actin total protein levels in control and detached retina 24 h and 7 days after experimental retinal detachment. …”

Analysis of rhodopsin level in LIRD mice treated with (±)-RPE65-61. by Yuhong Wang (85102)

“…(A) Expression levels of opsin in the retinas of control and LIRD mice were measured using anti-rhodopsin (1D4) antibody. …”

Differential effects of E2 on the functional coupling of C6 and F98 cells. by Zahra Moinfar (2504494)

“…<p>a) Significant decrease of coupling of C6 cells and b) Significant increase of coupling of F98 cells after E2 treatment. …”

Co-cultures of RGCs and Müller cells. by Xandra Pereiro (3924971)

“…The data represent the mean ± SEM. Scale bar = 100 μm, *p<0.05.</p>…”

Comparing inter-rater agreement for IQ dimensions in terms of motivation by assessors’ groups. by Marko Poženel (14019907)

“…The figure depicts all IQ dimensions and the mean value of the aforementioned dimensions. ICC values above the identity line (i.e. the dotted diagonal) represent an increase in ICC, while values below represent a decrease in ICC, when comparing unmotivated (Q4) and motivated (Q1) groups.…”

Impaired osteoclastogenesis in Cx43cKO fractures. by Alayna E. Loiselle (151690)

“…Cx43cKO fractures have significantly decreased Osteoclast number and Osteoclast surface at 28 days relative to WT. (*) indicates p<0.05 between groups at a given time-point, n=4 specimens/genotype/ time-point. …”

Vesicular zinc storage is modified by mutants that affect tyrosine-mediated ZnT3 oligomer formation. by Gloria Salazar (179015)

“…A) PC12 cells non transfected (NT) and cells expressing mouse ZnT3HA or myc-tag human ZnT1, 3, 4, 5 and 7 were stained with zinquin and fluorescence analyzed by flow cytometry, results are express as mean±SD in three independent experiments for human ZnTs. hZnT1: 112±26.5, hZnT3: 241±51.3, hZnT4: 169±9.7, hZnT5 227±20.3, hZnT7: 124±4.19. …”

Effect of the application of ultrasound on sarcoplasmic proteins from giant squid (Dosidicus gigas) mantle by Enzo ALDORADIN-PUZA (10462576)

Quality of Wood and Charcoal from Eucalyptus Clones for Metallurgical Use by Diego Correa Ramos (7476458)

TRPS1 directly represses regulatory element activity. by Thomas G. Scott (4092892)

“…C: Bar charts of prevalence of a representative GATA motif in increased, unchanged, and decreased peaks from (A). …”

Motor activity defects in old Gas7-deficient mice. by Bo-Tsang Huang (162584)

“…Data points are mean ± SEM, ***<i>P</i><0.001. (B) Adult Gas7-deficient mice performed no differently in regards to latency time than wild-type mice in four independent rotarod tests performed at constant speed (n  = 22) (left panel). …”

Changes in the perinuclear actin stress fibers and nuclear geometry for different rigidities. by Renu Vishavkarma (633732)

“…<p>(a–d) The observed decrease in stress fiber density as function of substrate rigidity for substrates with elastic modulus 65 kPa, 23 kPa, 5 kPa and 3 kPa respectively (also see panel in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107895#pone.0107895.s011" target="_blank">Fig. …”

Data partition and aggregation procedures. by Itziar Frades (741552)

“…<p>A random partition of the data into mutually exclusive sets P₁, P₂, P₃, P₄ and P₅ is done. …”

Supplemental Figures 1-7 from Erlotinib Pretreatment Improves Photodynamic Therapy of Non–Small Cell Lung Carcinoma Xenografts via Multiple Mechanisms by Shannon M. Gallagher-Colombo (14918058)

“…Supplemental Figure 4. VEGF levels decrease in A549 tumors with pre-PDT administration of erlotinib Supplemental Figure 5. …”

Lack of cluster formation upon unilateral PLL addition. by Yuri N. Antonenko (241873)

“…<p>Unilateral PLL addition at a concentration of 2.5 µM per lysine monomer, only has a minor effect on the lifetime <i>τ_P</i> of OPg dimers even at 1 M KCl on the opposite side. …”

Signalling via the Ras-RAF arm of ERK-MAPK is required for HCMV reactivation. by Verity G. Kew (577428)

“…IE RNA expression was expressed as a fold decrease compared to mock treated control <b>C</b>) immature DCs (1) were incubated with DMSO (2,3) or ERK (4,5), tpl2 (6,7) and Raf (8,9) inhibitors for 1 hour then stimulated with LPS (black) or IL-6 (grey) to promote reactivation. …”