The inhibitor of miR-21 inhibited miR-21-inducing expression of HIF-1α and VEGF, activation of AKT and ERK1/2, and angiogenesis. by Ling-Zhi Liu (20849)

“…(E) The number of blood vessels were counted from replicate experiments, and normalized to that of the control group as relative angiogenesis. The data are the mean ±SD from 6 replicate experiments. ##, indicates the significant decrease when compared to that of the control (<i>p</i><0.01).…”

Selective cytotoxicity of AQHAR in human cancer cells. by Kejuan Li (2580184)

“…<p>(A) Cell viability of human cancer and normal cells treated with indicated doses of AQHAR. …”

Effect of signaling pathway inhibitors on ox-LDL-induced Klotho downregulation in proximal tubular cells. by Cristina Sastre (503532)

“…<p>Pretreatment of MCT with parthenolide (1 µM) or PD098059 (50 µM) for 1 hour attenuates the decrease in Klotho mRNA (<b>A</b>) and protein (<b>B</b>) induced by ox-LDL (25 µg/mL). …”

rAd-p53 induced apoptosis was reverted by Fbxw7-specific siRNA. by Kangsheng Tu (428934)

“…C) The percentage of apoptotic Hep3B cells infected with rAd-p53 was decreased by Fbxw7-specific siRNA. Values are mean±standard error, n=3. * <i>P</i><0.05 <i>vs</i> control; ** <i>P</i><0.05 <i>vs</i> Fbxw7 siRNA; *** <i>P</i><0.05 <i>vs</i> rAd-p53.…”

Impaired myogenic differentiation in myotubes from SMA patients. by Nicole Hellbach (5562965)

“…<p>Representative fluorescence microscopy showing myotubes stained for MYOG, MYH1E and TNNT as well as cell nuclei (Hoechst) and quantification of the positively stained cells showing significant decrease of the later developmental markers in SMA Type 1 cells (A). …”

BV modulates GSK3β-mediated suppression of Foxp3⁺ Treg cells <i>in vitro</i>. by Ran Fu (434520)

“…<p>(A), Representative flow cytometric results of Foxp³⁺ Treg cells in cultured splenocytes after incubation with BV or transfection with GSK3β siRNA for 72 h. …”

Dramatic reduction of Dystrophin Dp71 expression in detached retina. by Abdoulaye Sene (258556)

“…<p>A: Western blot analysis of Dp71 and β-Actin total protein levels in control and detached retina 24 h and 7 days after experimental retinal detachment. …”

Analysis of rhodopsin level in LIRD mice treated with (±)-RPE65-61. by Yuhong Wang (85102)

“…(A) Expression levels of opsin in the retinas of control and LIRD mice were measured using anti-rhodopsin (1D4) antibody. …”

Differential effects of E2 on the functional coupling of C6 and F98 cells. by Zahra Moinfar (2504494)

“…<p>a) Significant decrease of coupling of C6 cells and b) Significant increase of coupling of F98 cells after E2 treatment. …”

Co-cultures of RGCs and Müller cells. by Xandra Pereiro (3924971)

“…The data represent the mean ± SEM. Scale bar = 100 μm, *p<0.05.</p>…”

Comparing inter-rater agreement for IQ dimensions in terms of motivation by assessors’ groups. by Marko Poženel (14019907)

“…The figure depicts all IQ dimensions and the mean value of the aforementioned dimensions. ICC values above the identity line (i.e. the dotted diagonal) represent an increase in ICC, while values below represent a decrease in ICC, when comparing unmotivated (Q4) and motivated (Q1) groups.…”

Motor activity defects in old Gas7-deficient mice. by Bo-Tsang Huang (162584)

“…Data points are mean ± SEM, ***<i>P</i><0.001. (B) Adult Gas7-deficient mice performed no differently in regards to latency time than wild-type mice in four independent rotarod tests performed at constant speed (n  = 22) (left panel). …”

Distinct decoy effects in two groups of subjects identified by clustering based on all decoy-effect indices. by Mehran Spitmaan (7495811)

“…Subjects in the first group (N = 72) selected the target with a probability larger than 0.5 for all decoy types (increased risk aversion), whereas subjects in the second group (N = 58) selected the target with a probability smaller than 0.5 (decreased risk aversion). …”

Implication of DNA Demethylation and Bivalent Histone Modification for Selective Gene Regulation in Mouse Primordial Germ Cells by Kentaro Mochizuki (131326)

“…We also obtained evidence showing that methylation of the regulatory region of <em>mil-1</em> resulted in 2.5-fold decrease in expression in a reporter assay. …”

Behavior analysis in wild type and CHOP−/− mice with or without tunicamycin treatment. by Chang-Mu Chen (315897)

“…<p>(A). Passive avoidance was performed 1 day before and 5 days after administration of tunicamycin (0.1 mg/ml) in wild type and CHOP−/− mice. …”

Impaired osteoclastogenesis in Cx43cKO fractures. by Alayna E. Loiselle (151690)

“…Cx43cKO fractures have significantly decreased Osteoclast number and Osteoclast surface at 28 days relative to WT. (*) indicates p<0.05 between groups at a given time-point, n=4 specimens/genotype/ time-point. …”

TRPS1 directly represses regulatory element activity. by Thomas G. Scott (4092892)

“…C: Bar charts of prevalence of a representative GATA motif in increased, unchanged, and decreased peaks from (A). …”

Mrj knockout shows reduced Orb2 oligomers. by Meghal Desai (15201231)

“…The data underlying this figure are available at: <a href="https://figshare.com/s/f5d913a0a289339ee16b" target="_blank">https://figshare.com/s/f5d913a0a289339ee16b</a>.…”

Increasing Notch1 activity in MAFs suppresses tumor angiogenesis. by Hongwei Shao (493627)

“…<i>Top</i>: representative images; <i>Bottom</i>: relative blood vessel density calculated as % of red pixel in total area examined by confocal microscopy. Data are mean ± SD, n = 5 tumors/group. <b>B.</b> Significantly decreased blood vessel density is observed in 1205Lu co-grafted with N1^IC-GFP/MAF. …”

Simulation of mantling by one colony in an average territory over 100 years. by Walter R. Tschinkel (2765)

“…Approximately 0.35 to 0.5 cm accumulate per millennium, with a mean of about 0.43 cm.…”