Fasudil Protects the Heart against Ischemia-Reperfusion Injury by Attenuating Endoplasmic Reticulum Stress and Modulating SERCA Activity: The Differential Role for PI3K/Akt and JAK... by Yapeng Li (124282)

“…The results showed that during the reperfusion period following 45 min of coronary ligation the infarct size (IS) increased from 3 h of reperfusion (45.4±5.57%) to 24 h reperfusion (64.21±5.43, P<0.05), which was associated with ER stress dependent apoptosis signaling activation including CHOP, Caspase-12 and JNK (P<0.05, respectively).The dynamic ER stress activation was also related to impaired SERCA activity at 24 h of reperfusion. …”

Image_7_Wheat F-box Protein TaFBA1 Positively Regulates Plant Drought Tolerance but Negatively Regulates Stomatal Closure.tif by Jie An (543888)

“…Based on these results, we suggest that TaFBA1-regulated ABA insensitivity may be dependent on regulating ABA-mediated gene expression through interacting with RCAR1 and ABI5. Increased antioxidant competence and decreased ROS accumulation may be an important mechanism that underlies improved drought tolerance in TaFBA1 OE plants.…”

Loss of Sirt3 in BMCs increases apoptosis in post-MI mice. by Heng Zeng (324703)

“…<p><b>A and B</b>. Western blot analysis demonstrating that treatment of post-MI mice with BMCs resulted in a significant increase in autophagy gene beclin-1 expression (A) and LC3-II/I ratio (B). …”

Interactions between Water Evaporation and Surface Cracking in NaCl-Induced Homogeneous Silt Loam and Sand by Xuguang Xing (12455819)

“…In addition, the water content for both two types of samples first rapidly decreased and then entered a stable state during evaporation; however, silt loam soil moisture experienced a “second decline” when surface crack developed rapidly. …”

<em>Nigella sativa</em> (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors by Swantje C. Duncker (154707)

“…DAMGO, in contrast, had no effect on mast cell parameters but decreased IFNγ, IL-4, IL-5, and IL-10 concentration after <em>ex vivo</em> re-stimulation of mesenteric lymphocytes. …”

Comparison of changes in transcript abundance following wt DENV infection and TDV immunization. by Fiona R. Strouts (2805394)

“…<p>A) Hierarchical clustering of 135 genes whose transcripts differ in abundance over time following wt infection of sham-immunized animals (FDR<0.05, fold-change≥1.3). …”

The current and future potential soil organic carbon stocks of vegetated coastal ecosystems in the Bohai Rim, China by Shaobo Sun (9231194)

“…I projected that climate changes, sea level rise (SLR), and anthropogenic disturbances would jointly reduce 10.9% and 13.1% of SOC stocks in the VCEs during 2041-2060 under the Shared Socioeconomic Pathway 245 (SSP245) and SSP585 scenarios, respectively; decreased 20.5% and 22.3% of the SOC stocks during 2081-2100 under the SSP245 and SSP585 scenarios, respectively. …”

Representative gross and histological images of excised tumors in each treatment group. by Yukihiko Hiroshima (568068)

“…Scale bars: 5 mm (A and B), 250 µm (C and D).</p>…”

The position of Ho after the injection. by Mehrdad Khoshnevis (8991434)

“…<p>(A, B) Significant tumor growth from the day of TP preparation (D10) and the day of Ho injection (D14), (C) 3D image of the injected Ho inside the tumor in pig n° 3, (D,E,F) Pig n° 5, injected Ho inside the tumor. …”

Bone metabolism dynamics in the early post-transplant period following kidney and liver transplantation by Peter W. Schreiber (4042775)

“…Six months post-transplant median 1, 25-(OH)₂ vitamin D levels increased by >300% (from 9.1 to 36.5ng/l; <i>P</i><0.001) and median intact parathyroid hormone levels decreased by 68.4% (from 208.7 to 66.0 ng/l; <i>P</i><0.001). …”

Inhibition of actin perturbs the kinetics of dynamin recruitment, but has minimal impact on GAK recruitment. by Marcus J. Taylor (173337)

“…<p>(A) Acute inhibition of actin decreased the amplitude of peak dyn1(WT)-mCherry recruitment. …”

Spontaneous bursting in model PCs. by Erin C. McKiernan (4532161)

“…<i>a</i>_<i>DK</i> decreasing from 8000 to 6000 pA (8 to 6 nA) in steps of 500 pA, as indicated in (A.)…”

Effects of correlation shaping on the propagation of neural activity. by Ashok Litwin-Kumar (135071)

“…However, the neuron with the slow time constant showed a decreased firing rate in the high state.</p>…”

Expression of c-Myc and Akt induces stem cell marker expression in primary p53^−/− astrocytes. by Josefine Radke (281457)

“…<p>Control cultures (p53Crtl) showed no stem cell marker expression (A I–A IV) and strong GFAP-IR (A V). All oncogene-transduced astrocyte cultures showed a significantly decreased GFAP-IR in early passages (2^nd) (B V, D V, F V) and complete loss of GFAP-IR in late (12^th) passages (C V, E V, G V) and induced expression of nestin (B II–G II). …”

HeathlandCycle_Management.jpg by Liv Guri Velle (3281691)

Relates to Fig 2. by He Liu (67509)

“…<p><b>SI data in mice used to measure day or nighttime spontaneous firing in cells</b>^{<b>LHb→DRN</b>}<b>. (A)</b> Susceptible mice used for day or <b>(B)</b> nighttime in vitro recording of labelled cells^LHb-DRN display: decreased SI ratio (day—<i>F</i>_2,24 = 28.02, <i>P</i> < 0.0001; <i>n =</i> 7–11 mice/group; night—<i>F</i>_2,12 = 8.959, <i>P</i> < 0.01; n = 4–6 mice/group) (left). …”

Table_1_Prediction of Fluid Responsiveness by the Effect of the Lung Recruitment Maneuver on the Perfusion Index in Mechanically Ventilated Patients During Surgery.DOCX by Sunthiti Morakul (8930354)

“…ΔPI_LRM had the highest AUC [0.81 (0.66–0.97)] to predict FR with a cut-off value of 40% (sensitivity 92.3%, specificity 73.7%).…”

Ability of WT and mutant HBc or WHc to support HBV replication in the <i>trans</i>-complementation assay. by Xupeng Hong (12599281)

“…<b>(G)</b> Summary of all parameters of HBV replication in HepG2 (shown in <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010739#ppat.1010739.g006" target="_blank">Fig 6</a></b>) and WCH-17 cells. …”

Ability of WT and mutant HBc or WHc to support WHV replication in the <i>trans</i>-complementation assay. by Xupeng Hong (12599281)

“…<b>(G)</b> Summary of all parameters of WHV replication in HepG2 and WCH-17 cells (shown in <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010739#ppat.1010739.g006" target="_blank">Fig 6</a></b>). …”

Statistics for modules with eigengenes that correlated significantly with pCO₂ concentration. by Laura H. Spencer (14025963)

“…Modules are randomly assigned color names, and the letters correspond to <a href="/article/info:doi/10.1371/journal.pclm.0000319#pclm.0000319.g005" target="_blank">Fig 5</a> panels in the main text.…”