The synergistic effect of HDAC and proteasome inhibition is consistent within each drug class. by Aimée N. Laporte (3617987)

Image_1_Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.JPEG by Tongtong Wang (775312)

“…As a result, APα-induced an increase in the number of TH-positive SH-SY5Y cells might be mediated through GABAAR via Ca²⁺/CaM/CaMKIIδ3/BDNF (CDK1) signaling pathway, which would ultimately facilitate to elucidate PD pathogenesis and hold a promise as an alternative therapeutic target for PD.…”

Image_1_Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.JPEG by Tongtong Wang (775312)

“…As a result, APα-induced an increase in the number of TH-positive SH-SY5Y cells might be mediated through GABAAR via Ca²⁺/CaM/CaMKIIδ3/BDNF (CDK1) signaling pathway, which would ultimately facilitate to elucidate PD pathogenesis and hold a promise as an alternative therapeutic target for PD.…”

Image_2_Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.JPEG by Tongtong Wang (775312)

“…As a result, APα-induced an increase in the number of TH-positive SH-SY5Y cells might be mediated through GABAAR via Ca²⁺/CaM/CaMKIIδ3/BDNF (CDK1) signaling pathway, which would ultimately facilitate to elucidate PD pathogenesis and hold a promise as an alternative therapeutic target for PD.…”

Image_2_Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.JPEG by Tongtong Wang (775312)

“…As a result, APα-induced an increase in the number of TH-positive SH-SY5Y cells might be mediated through GABAAR via Ca²⁺/CaM/CaMKIIδ3/BDNF (CDK1) signaling pathway, which would ultimately facilitate to elucidate PD pathogenesis and hold a promise as an alternative therapeutic target for PD.…”

Training loss raw data. by Jack B. Maguire (5123183)

Decreased Expression of GATA2 Promoted Proliferation, Migration and Invasion of HepG2 In Vitro and Correlated with Poor Prognosis of Hepatocellular Carcinoma by Yi-Wei Li (441347)

“…Decreased expression of intratumoral GATA2 protein significantly correlated with elevated alpha feto-protein (p = 2.7E-05), tumor size >5 cm (p = 0.049), absence of tumor capsule (p = 0.002), poor differentiation (p = 0.005), presence of tumor thrombi (p = 0.005) and advanced TNM stage (p = 0.001) and was associated with increased recurrence rate and decreased overall survival rate by univariate (p = 1.6E-04 for TTR, p = 1.7E-04 for OS) and multivariate analyses (HR = 0.63, 95% CI = 0.43–0.90, p = 0.012 for TTR; HR = 0.67, 95% CI = 0.47–0.95, p = 0.026 for OS). …”

Time course of the SARS-CoV-2 pandemic up to 7 November 2020 for the seven regions in England in the constant IFR model. by Siyu Chen (278663)

A simplified scheme of 5α/β-reduced C19 steroid biosynthesis in human, “backdoor pathway”. by Antonín Pařízek (3142470)

A simplified scheme of 5α/β-reduced C19 steroid biosynthesis in the human “frontdoor pathway”. by Antonín Pařízek (3142470)

Changes in central metabolism in <i>V. cholerae</i> Δ<i>nqrA-F</i> mutant. by Yusuke Minato (263245)

Cold-fractured cross sections of Sample 4 (A), Sample 5 (B), Sample 6 (C) (see by Kyungwho Choi (300480)

Miz1 Deficiency in the Mammary Gland Causes a Lactation Defect by Attenuated Stat5 Expression and Phosphorylation by Adrián Sanz-Moreno (172726)

“…Further analysis revealed decreased Stat5 activity in <i>Miz1</i>Δ<i>POZ</i> mammary glands and an attenuated expression of Stat5 targets. …”

Data_Sheet_1_A Dual Role for Death Receptor 5 in Regulating Cardiac Fibroblast Function.PDF by Miles A. Tanner (11353644)

“…To investigate the impact of DR5 regulation of fibroblasts in vivo, a chronic isoproterenol administration model of heart failure was used. …”

Table_5_Low Virulence of the Fungi Escovopsis and Escovopsioides to a Leaf-Cutting Ant-Fungus Symbiosis.XLSX by Débora Mello Furtado de Mendonça (11201688)

Liver ischemia/reperfusion injury, a setting in which the functional mass is reduced and the role of PDE5 inhibitor by Prof. Dr. Hesham N. Mustafa (664724)

Theta and alpha coherence changes across all five vibration conditions for a specific seed region of interest. by Kara M. Donovan (21445866)

Cisd2KO mice exhibit cardiac electromechanical dysfunctions that are similar to those observed in the naturally aged WT mice. by Chi-Hsiao Yeh (7474556)

“…Mouse number <i>n</i> ≥ 5 for each group. Values for each data point can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000508#pbio.3000508.s001" target="_blank">S1 Data</a>. 3M, 3 months old; 6M, 6 months old; 26M, 26 months old; APC, atrial premature complex; AV, atrioventricular; Cisd2KO, CDGSH iron-sulfur domain-containing protein 2 KO; ECG, electrocardiography; KO, knockout; MRI, magnetic resonance imaging; QTc, corrected QT; VPC, ventricular premature complex; WT, wild type.…”

image_5_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

DataSheet5_LMO3 downregulation in PCa: A prospective biomarker associated with immune infiltration.PDF by Wenchao Xu (2629939)