Table_1_Altered Transcription Factor Expression Responses to Exercise in Insulin Resistance.DOCX by Rocio Zapata-Bustos (10533320)

“…Q-rt-PCR analysis of RNA and immunoblot analysis from pre- and post-exercise muscle biopsies revealed several transcription and growth factors that had altered responses to exercise in insulin resistant participants. A significant increase (EGR3 and CTGF) and decrease (RELA and ATF2) in the mRNA expression of transcription and growth factors was found after exercise in the lean group, but not in the obese participants.…”

Test of the most likely period associated with orang-utan population decline. by Reeta Sharma (117636)

“…Note that LK Lot2 is Lower Kinabatangan Lot2 population. b) As 5a), and plotted for the last 5 kya. c) H1 to H4 represents four different hypotheses tested, each corresponding to one of the four factors and time periods that may have led to orang-utan population collapse (discussed in the text). …”

La protein expression promotes proliferation and cell cycle progression of SCC 22B cells. by Gunhild Sommer (13580)

“…<p><b>(A)</b> Lower La expression in siRNA-mediated SCC 22B cells (see Western blot analysis in inlet) correlates with decreased proliferation rate (dotted line). …”

Data_Sheet_1_Age-Dependent Association Between Cognitive Reserve Proxy and Longitudinal White Matter Microstructure in Older Adults.PDF by Rostislav Brichko (12515060)

“…We also examined whether the relationship between the proxy CR composite score and white matter microstructure was modified by participant age, APOE-ε4 genetic status, and level of vascular risk.</p>Methods<p>A sample of 192 non-demented (n = 166 cognitively normal, n = 26 mild cognitive impairment) older adults [mean age = 70.17 (SD = 8.5) years] from the BIOCARD study underwent longitudinal DTI (mean follow-up = 2.5 years, max = 4.7 years). …”

Relative expression of genes encoding enzymes in the lactose synthesis pathway. by Danielle G. Lemay (105771)

“…Color denotes change in gene expression from colostrum to transitional (Panel A) or transitional to mature (Panel B): red = significant increase; green = significant decrease; and yellow = no significant change in gene express levels between stages. …”

Data_Sheet_1_Pyrite-Based Cr(VI) Reduction Driven by Chemoautotrophic Acidophilic Bacteria.docx by Xinxing Liu (209373)

“…The highest reduction efficiency was achieved in the biological system with a pH range of 1–1.5. Pyrite dissolution and reactive site regeneration were promoted by A. ferrooxidans, which resulted in the enhanced effect in Cr(VI) reduction. …”

Simulations Demonstrating the Effects of Varying the Degree of Resistance on Treatment Success Rates by Marcel E Curlin (32388)

“…<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g005" target="_blank">Figures 5</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g006" target="_blank">6</a>, (A) and (C) demonstrate success rates as the duration of induction therapy is increased, and (B) and (D) demonstrate success rates over a range of induction therapy/therapy intensification start times. …”

Modeling the RA Morphogen Gradient by Richard J White (82003)

“…Values of parameters that differed between panels were β = 1 ([A–E] and solid curve in [G]) or 0.5 ([F], [H], and dashed curve in [G]); <i>x</i>_f = 400 μm ([A–C] and [F–H]) or 450 μm (D–E); <i>f</i>₀ = 0 (B), 400 ([A], [C], [F–H], and solid curves in [D] and [E]), or 1,100 (dashed curves in [D] and [E]); <i>k</i>_deg = 500 sec⁻¹ ([A] and [C–G]) or 0.03 sec⁻¹ (B); <i>k</i>_max = 0.001 ([A] and [C–G]) or 4 (B); <i>V</i>(<i>x</i>) = 5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise ([A], [D], [E], and solid curves in [B], [C], and [G]), 2.5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise (dashed curves in [B] and [C]), 0.2 for all <i>x</i> ([F], dashed curve in [G], and solid curve in [H]), or 0.1 for all <i>x</i> (dashed curve in [H]).…”

Inhibition of the Hedgehog pathway partially rescues pancreas formation in pancreas with activated β-catenin signaling. by Jose Luis Muñoz-Bravo (3220134)

“…<p>Increased Shh expression in the embryonic (E13.5) epithelium of <i>Pdx1-Cre; Ctnnb1</i>^{<i>tm1Mmt/+</i>} pancreas (B) compared to control pancreata (A). …”

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. by Melinda L. Tursky (20790436)

“…<p>A: The detection rate of reference standard variants ranging from 0.0008 to 0.1 VAF at 500-5,000 × depth. …”

Data_Sheet_1_The Responses of Germ-Free Zebrafish (Danio rerio) to Varying Bacterial Concentrations, Colonization Time Points, and Exposure Duration.docx by Fang Tan (353838)

“…The results indicated that the final bacteria concentrations ranging from 10² to 10⁴ CFU/ml did not cause any mortality when GF mono-associated larvae were exposed to either E. coli DH5α or B. subtilis WB800N at 3 or 5 dpf, while concentrations ranging from 10⁶ to 10⁷ CFU/ml increased the mortality, particularly for 5 dpf owing to the decrease in dissolved oxygen level. …”

Complementary conditioning measures across the clinical study groups. by Gabriela Ribeiro (4748373)

“…<b>(F) Intake</b> was similar across conditioning for CS^- and CS⁺ flavors (F_{(1, 50)} = 0.5, <i>P</i> = 0.5) and despite findings of a significant group effect (F_{(1, 50)} = 7.5, <i>P</i> = 0.001), interaction between factors was not significant (F_{(2, 50)} = 1.0, <i>P</i> = 0.4; mixed-model 2-way ANOVA). …”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

DataSheet_1_Treatment With Lipopolysaccharide Induces Distinct Changes in Metabolite Profile and Body Weight in 129Sv and Bl6 Mouse Strains.docx by Maria Piirsalu (8627697)

“…According to the general linear model analysis (GLM), the 1.5 h LPS challenge in Bl6 caused a decrease of propionylcarnitine (C3), glucogenic amino acids, and acetylornithine (Ac-Orn), whereas the response of 129Sv included decreased concentrations of short-chain acylcarnitines (SCACs), citrulline, and elevation of glycerophospholipid (PCaa C42:0) and sphingolipid [SM(OH)C16:1]. 24 h after LPS administration, robust alterations in lipid profile were observed in both strains. …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

Crosstalk between IIS and TGF-β signaling pathways. by Sri Devi Narasimhan (223914)

“…For the dauer assays, error bars indicate the standard deviation among the different plates within one experiment. (A) Lifespan graph showing the opposite effects of <i>daf-3</i> and <i>daf-5</i> mutations in a <i>daf-2(e1370)</i> background. …”

Urea and salt as supplementary diet for crossbreed milk cows by César Roberto Viana Teixeira (8402268)

“…Ten animals were used, mean body weight 480 kg ± 9,7, distributed in a 5 x 5 double Latin square, with treatments of supplements with different urea and mineral salt percentages, namely, 10:10; 10:20; 20:10 and 20:20, completed to 100% with corn meal. …”

sCD25 inhibits IL-2R signalling by sequestering secreted IL-2. by Shane E. Russell (303031)

“…<p>(<b>A–D</b>) Purified naive CD4+ T cells activated for 24 hrs under Th17 inducing conditions in the presence or absence of sCD25 and examined for levels of (<b>A</b>) p-Stat5 pY694, (<b>B</b>) intracellular IL-2 expression (<b>C</b>) surface binding of sCD25-His and (<b>D</b>) surface expression of endogenous CD25 by FACS analysis. …”

Table_3_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…According to the fold changes, the top ten upregulated miRNAs were miRNA-543-3p, miRNA-802-5p, miRNA-493-3p, miRNA-539-3p, miRNA-495, miRNA-380-5p, miRNA-214-5p, miRNA-539-5p, miRNA-190a-3p, and miRNA-431. …”

Table_2_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…According to the fold changes, the top ten upregulated miRNAs were miRNA-543-3p, miRNA-802-5p, miRNA-493-3p, miRNA-539-3p, miRNA-495, miRNA-380-5p, miRNA-214-5p, miRNA-539-5p, miRNA-190a-3p, and miRNA-431. …”