Packaging of multiple cleavage enzymes that target different HBV regions enhances potency and decreases resistance. by Joshua T. Schiffer (430730)

“…<p>Simulation of HBV eradication employing gene therapy following a single dose. Each data point represents number of remaining infected cells (y-axis) after a simulation with one of 36 unique parameter sets. x-axis is functional multiplicity of infection (fMOI). …”

Decreased endothelial function in a subfailure overstretch RA model was restored with apyrase and P2X7R antagonists FCF and A740003. by Padmini Komalavilas (402160)

GUCY2C ligand supplementation decreases intestinal permeability and susceptibility to DSS-induced colitis. by Jieru Egeria Lin (181534)

Metformin/rifampicin combination decreases <i>S</i>. <i>aureus</i> load and persisters in Mice. by Xiao-Qi Lin (9548375)

Heterozygous TIN2-R282H mutation decreases the frequency of telomere extension by telomerase. by Amanda K. Frank (778017)

miR-200b reverses EMT and decreases invasion and metastasis by PC3 cells. by LaTanya V. Williams (504683)

Proportion of slightly-deleterious insertions as a function of population size. by Thomas LaBar (739568)

HLA-C expression levels increase and exon 1 skipping decreases as NK cells mature. by Hongchuan Li (375905)

TreeView Images of Examples of Great Ape and HLS Gene Copy Number Increases and Decreases by Andrew Fortna (4005)

“…Estimates of the time at which indicated branch points occurred during hominoid evolution are derived from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020207#pbio-0020207-Chen1" target="_blank">Chen and Li (2001)</a>.…”

Origin firing efficiency is decreased for all replication origins when Pol α levels are reduced. by Sarina Y. Porcella (8811746)

Descriptive statistics of all results at baseline after a full night of sleep (0 h), after 12 (-12 h), 24 (-24 h) and 36 (-36 h) hours of total sleep deprivation followed by 8 (+8... by Jan Maleček (17396660)

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

Adjusted association of demographic factors with SDOH scores among Arkansans overall and by race and ethnicity from September 5, 2020 to December 18, 2020^a^,<s... by Jenil R. Patel (3639451)

Inducible expression of <i>EVI1</i> decreases the sensitivity of HL-60 cells to daunorubicin. by Anna Rommer (241040)

Functional characterization of the V9D and R10C substitutions in chicken ARF. by Doreen Schwochow Thalmann (3912649)

“…Spectra of all peptides in free form and at 25 μM concentration in complex with MDM2_204-298 are shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006665#pgen.1006665.s008" target="_blank">S5 Fig</a>. …”

A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes by Sharon Cresci (53599)

“…Consistent with previous descriptions of PPARα in experimental models and human disease, we describe a novel <em>PPARA</em> promoter SNP that decreases transcriptional activation of <em>PPARA</em> and protects against mortality in diabetic patients after ACS.…”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Nitric Oxide Oxidatively Nitrosylates Ni(I) and Cu(I) <i>C</i>-Organonitroso Adducts by Stefan Wiese (1626535)

“…[Me₂NN]Cu(NCMe) reacts with 0.5 equiv of ArNO in ether to give the dinuclear adducts {[Me₂NN]Cu}₂(μ-η²:η¹-ONAr) (<b>2a</b> and <b>2b</b>), which exhibit η² and η¹ bonding of the ArNO moiety with separate [Me₂NN]Cu fragments possessing N−O distances of 1.375(6) Å (<b>2a</b>) and 1.368(2) Å (<b>2b</b>). …”

Nitric Oxide Oxidatively Nitrosylates Ni(I) and Cu(I) <i>C</i>-Organonitroso Adducts by Stefan Wiese (1626535)

“…[Me₂NN]Cu(NCMe) reacts with 0.5 equiv of ArNO in ether to give the dinuclear adducts {[Me₂NN]Cu}₂(μ-η²:η¹-ONAr) (<b>2a</b> and <b>2b</b>), which exhibit η² and η¹ bonding of the ArNO moiety with separate [Me₂NN]Cu fragments possessing N−O distances of 1.375(6) Å (<b>2a</b>) and 1.368(2) Å (<b>2b</b>). …”