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79341
Control of the Kinetic Signaling Behavior
Published 2013“…</p><p>(A and B) Same parameter values as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020003#pcbi-0020003-g005" target="_blank">Figure 5</a>A with the exception that the <i>constitutive</i> and <i>ligand-induced</i> degradation rates have been <i>decreased</i> and <i>increased</i> by a factor three, respectively: <i>k<sub>cd</sub> =</i> (3 × 36 min)<sup>−1</sup>; ligand-induced degradation <i>k<sub>lid</sub> =</i> (4/3 min)<sup>−1</sup>.…”
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79342
Table 1_Global, regional and national burden of pancreatic cancer and its attributable risk factors from 2019 to 2021, with projection to 2044.docx
Published 2025“…The age-standardized incidence rate was 6.0 (5.5 to 6.5) per 100,000 people in 2019 and decreased to 5.9 (5.4 to 6.4) per 100,000 people in 2021. …”
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79343
Data_Sheet_1_FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma.PDF
Published 2021“…Compared with non-silenced cells, a reduced acetyl-YY1 was found on the DR5 promoter, resulting in increased DR5 transcript levels. …”
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79344
Data Sheet 1_Global, regional and national burden of pancreatic cancer and its attributable risk factors from 2019 to 2021, with projection to 2044.docx
Published 2025“…The age-standardized incidence rate was 6.0 (5.5 to 6.5) per 100,000 people in 2019 and decreased to 5.9 (5.4 to 6.4) per 100,000 people in 2021. …”
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79345
Visual representations of trait changes across the KPB.
Published 2014“…<p>Top row, increase in VD as seen in (A), <i>“Dryophyllum” subfalcatum</i>, −30.7 m stratigraphic depth, VD = 2.5 mm<sup>−1</sup> and (B) unknown nonmonocot (morphospecies FU87), 1.275 m depth, VD = 5.3 mm<sup>−1</sup>. …”
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79346
Effect of cyclic biaxial strain and CaSR agonists on HAoSMC CaSR expression and phenotype.
Published 2015“…Data are represented on a logarithmic y-axis. Exposure to CaSR agonists (<i>Ca5</i>, <i>Gd</i>, <i>Gd2+Ca5</i>) significantly increased calcification, and this was reduced by cyclic strain. …”
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79347
Data_Sheet_1_Fracture Shape and Orientation Contributions to P-Wave Velocity and Anisotropy of Alpine Fault Mylonites.PDF
Published 2021“…The results from both models have comparable pore-free fast and slow velocities of 6.5 and 5.5 km/s, respectively. Introducing 5% fractures with 5:2:1 aspect ratio, oriented with the longest axes parallel to foliation decreases these velocities to 6.3 and 5.0 km/s, respectively. …”
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79348
Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration
Published 2016“…Targeted deletion of both <i>Gnat1</i> (a gene encoding the α subunit of the heterotrimeric G-protein transducin) and <i>Atg5</i> in the rod photoreceptors resulted in a significantly decreased rate of rod cell degeneration as compared to the <i>atg5</i><sup>Δ<i>rod</i></sup> mouse retina, and considerable preservation of photoreceptors. …”
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79349
Time series at stripe-edge positions.
Published 2017“…In general, repression decreases the occurrence of high initiation intervals and increases the frequency of low initiation intervals, compare (D) and (H) to the stripe-center (non-repressed) expression in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176228#pone.0176228.g005" target="_blank">Fig 5D</a>. …”
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79350
Potential effects of ursodeoxycholic acid on accelerating cutaneous wound healing - Fig 4
Published 2019“…<p><b>(A)</b> TGF-β1 immune-stained wounded skin sections revealing; decreased expression in at zero-day(a), significant increased expression in non-treated (b) and in UDCA-treated (c) wounds 5 days post wounding. …”
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79351
Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta
Published 2013“…DNA methylation (percentage points) was increased at CpG sites within genes encoding the glucocorticoid receptor (<i>NR3C1</i> exon 1D promoter; +8.46%; <i>P</i><0.01) and corticotropin releasing hormone (CRH) binding protein (<i>CRHBP</i> intron 3; +9.14%; <i>P</i><0.05), and decreased within <i>CRH</i> (5′ UTR; −4.30%; <i>P</i> = 0.11) in EOPET-associated placentae, but not in LOPET nor nIUGR cases, compared to controls. …”
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79352
Generation of VILIP-1 transgenic mice.
Published 2010“…<p>(A) K5-VILIP-1 construct. The two arrows above the β-globin intron box indicate the position of the specific primers used in PCR genotyping. …”
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79353
Lower incidence of fracture after IV bisphosphonates in girls with Rett syndrome and severe bone fragility
Published 2017“…Urinary calcium excretion decreased from 0.7 [0.18; 1.5] to 0.2 [0.03; 0.67] mM/mM of creatinine (p = 0.0001). …”
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79354
Diverse electrical behavior of model bursting neurons in response to changing temperature.
Published 2013“…<p>Examples that illustrate the diversity of firing patterns of simulated model neurons in response to changing temperatures from 23.5°C to 7°C. (A) Neuron that increases burst frequency as a function of temperature. …”
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79355
Contrast adaptation depends on terminal size: comparison of model and experiment.
Published 2014“…Graph shows release dynamics of OFF terminals with r<1 µm (red) and r>1.2 µm (black) in response to a 5 Hz stimulus (cf. (A)). (D) Adaptation index decreases linearly with terminal radius, as predicted by the model (<i>n</i> = 236 OFF terminals from seven fish, each bin is an average of 12 individual terminals). …”
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79356
Structural, Spectral, and Electrochemical Properties of Nickel(II), Copper(II), and Zinc(II) Complexes Containing 12-Membered Pyridine- and Pyridol-Based Tetra-aza Macrocycles
Published 2014“…In the solid-state, the Ni(II) complexes adopt a unique bimetallic and <i>cis</i>-octahedral (μ-Cl)<sub>2</sub> coordination sphere, and the electronic studies provide further evidence for the existence of a six-coordinate Ni(II) species in solution. …”
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79357
Structural, Spectral, and Electrochemical Properties of Nickel(II), Copper(II), and Zinc(II) Complexes Containing 12-Membered Pyridine- and Pyridol-Based Tetra-aza Macrocycles
Published 2014“…In the solid-state, the Ni(II) complexes adopt a unique bimetallic and <i>cis</i>-octahedral (μ-Cl)<sub>2</sub> coordination sphere, and the electronic studies provide further evidence for the existence of a six-coordinate Ni(II) species in solution. …”
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79358
Structural, Spectral, and Electrochemical Properties of Nickel(II), Copper(II), and Zinc(II) Complexes Containing 12-Membered Pyridine- and Pyridol-Based Tetra-aza Macrocycles
Published 2014“…In the solid-state, the Ni(II) complexes adopt a unique bimetallic and <i>cis</i>-octahedral (μ-Cl)<sub>2</sub> coordination sphere, and the electronic studies provide further evidence for the existence of a six-coordinate Ni(II) species in solution. …”
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79359
Structural, Spectral, and Electrochemical Properties of Nickel(II), Copper(II), and Zinc(II) Complexes Containing 12-Membered Pyridine- and Pyridol-Based Tetra-aza Macrocycles
Published 2014“…In the solid-state, the Ni(II) complexes adopt a unique bimetallic and <i>cis</i>-octahedral (μ-Cl)<sub>2</sub> coordination sphere, and the electronic studies provide further evidence for the existence of a six-coordinate Ni(II) species in solution. …”
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79360
Structural, Spectral, and Electrochemical Properties of Nickel(II), Copper(II), and Zinc(II) Complexes Containing 12-Membered Pyridine- and Pyridol-Based Tetra-aza Macrocycles
Published 2014“…In the solid-state, the Ni(II) complexes adopt a unique bimetallic and <i>cis</i>-octahedral (μ-Cl)<sub>2</sub> coordination sphere, and the electronic studies provide further evidence for the existence of a six-coordinate Ni(II) species in solution. …”