Rapid and Localized Mechanical Stimulation and Adhesion Assay: TRPM7 Involvement in Calcium Signaling and Cell Adhesion by Wagner Shin Nishitani (198823)

“…The cells showed adhesion and calcium response to the mechanical stimulation correlated to the degree of gel treatment: highest for fully treated gels and lowest for non-treated ones. TRPM7 inhibition by siRNA on HUVECs caused an increase in adhesion relative to control (no siRNA treatment) and non-targeting siRNA, but a decrease to 80% of calcium response relative to non-targeting siRNA which confirms the important role of TRPM7 in mechanotransduction despite the increase in adhesion.…”

Figure 4 by Seiya Tsujiuchi (24182)

“…The response magnitudes to 265 (C) and 350 (D) Hz stimuli are non-linear, they show the maximum only at intensities between 0.3–4 mm/s, and then decrease at intensities above 4 mm/s. …”

<i>In</i><i>situ</i> analysis for LAMA4⁺, TCF21⁺ and KCNJ1⁺ using confocal laser scanning microscopy. by Alessio Valletti (475962)

“…<p>RCC tumor tissues (T) were characterized by a significant increase of LAMA4 expression (<b>B</b>) and decrease of TCF21 (<b>E</b>) and KCNJ1 (<b>H</b>) expression as compared to non-tumoral (NT) kidney portion (<b>A</b>, <b>D</b>, <b>G</b>). …”

Cell-targeted <i>Trhn</i> RNAi in neurons and glia differential effects serotonin in the experience-dependent critical period. by Vanessa Kay Miller (19775496)

“…One-way ANOVA with Tukey’s multiple comparison shows a significant decrease in 5-HT in <i>elav-</i>Gal4 compared to <i>repo</i>-Gal4<i>-</i>driven UAS-<i>Trhn</i> RNAi (<i>n</i> = 10, <i>p</i> = 8.00 × 10⁻¹⁵). …”

Tumor Suppressor Function of the <i>SEMA3B</i> Gene in Human Lung and Renal Cancers by Vitaly I. Loginov (737026)

“…Using qPCR, we observed on the average 10- and 14-fold decrease of the <i>SEMA3B</i> mRNA level in SCC and ADC, respectively, and a 4-fold decrease in ccRCC. …”

Blood pressure variability in the elderly. Association between postprandial and sleeping periods by Fernando Abrão Garcia (4657036)

“…One 24 hours ambulatory blood pressure monitoring was used for measurements and the results were showed in the time-rate index. Results: We observed a decrease in the systolic blood pressure values from preprandial to postprandial and to the sleeping periods (124.7 ± 14.6, 113.2 ± 15.3 and 108.5 ± 13.9mmHg, respectively; p = 0.003). …”

Effect of sagopilone (SAG) on cell proliferation, tubulin cytoskeleton, cell cycle and apoptosis of lung cancer cells. by Sebastian Winsel (222664)

“…Proliferation was measured with crystal violet assay. Mean IC50 values as measure of the half-maximal growth inhibition and standard deviations are shown. 1B, Immunofluorescence staining of α-tubulin (green) and DNA (red) in A549 lung cancer cells after incubation with either vehicle (0.1% ethanol), 2.5 nM, or 40 nM SAG. …”

Phenomenological model links variability in sensory responses to response time. by Anders Ledberg (139974)

“…<p>(<b>A</b>) Example showing that an increase in variability leads to a decrease in mutual information. …”

Deletion of <i>pafr</i> reduces tactile allodynia. by Shigeo Hasegawa (249454)

“…<p>While wild-type mice with an L5 nerve injury showed a progressively decreased paw withdrawal threshold, <i>pafr</i>^−/− mice showed an attenuation of the decrease in paw withdrawal threshold after nerve injury. …”

OCT imaging during ON in MOG^TCRxThy1CFP mice by Katie Lidster (479714)

“…<p>(A) Histological changes in the thickness of RGC layer in control mice (n=5) and MOG^TCRxThy1CFP mice (n=5) at day 21. …”

Relationship between anterior segment and optic nerve head parameters in healthy subjects by Ali Bulent Cankaya (4643500)

“…A 1-mm3 increase in anterior chamber depth corresponded to a 0.154-mm3 decrease in rim volume. …”

Aging-related limit of exercise efficacy on motor decline - Fig 7 by Jennifer C. Arnold (4621795)

“…</b> TH standard was loaded from 0.5 to 4 ng. A non-exercise (NE) and exercise (E) result is shown representing the overall ~25% decrease in TH expression in the exercise group. …”

Effects of exercise on cations/anions in blood serum of English Thoroughbred horses by R.O.F. Prado (6935750)

“…Potassium ion showed increase 30min after exercise and decrease 60min after. Chloride ion showed a decrease 30min after exercise, to recover gradually 60min after. …”

The NOD1 agonist iE induces NF-κB activation and apoptosis in cardiomyocytes and H9c2 cells. Effect of NOD1 ablation with siRNAs. by María Fernández-Velasco (105894)

“…(B) iE induces a decrease in cardiomyocyte viability in a dose-response form. …”

The effects of pretreatment with fingolimod-phosphate on BMECs in the presence of MS sera. by Hideaki Nishihara (545149)

“…Pretreatment with fingolimod-phosphate resulted in an increase in the claudin-5 protein levels (B) and TEER values (G) and a decrease in the VCAM-1 protein levels (F) in the BMECs, which were upregulated after exposure to the sera from all MS patients, including the RRMS-R, RRMS-S and SPMS patients, compared to that observed in the cells not pretreated with fingolimod-phosphate.…”

Effect of α-synuclein siRNA on α-synuclein protein in the monkey substantia nigra. by Alison L. McCormack (362670)

“…Data are expressed as percent of the control value in the right (untreated) substantia nigra and represent mean ± SEM. A significant decrease is caused by α-synuclein but not luciferase siRNA in the left (siRNA-infused) hemisphere. …”

FGF-9 Inhibits Infarct and Fibrosis in the Post-MI Diabetic Myocardium. by Dinender K. Singla (462521)

“…<b>G</b>: Histogram of quantitative infarct size analysis suggests a significant decrease in infarct size in the MI+FGF-9 group compared to the MI group. …”

Line diagrams of the development of individual values of perfusion MRI parameters of tumor microcirculation in the therapy and the control group. by Ralf S. Eschbach (691194)

“…</b> Note the significant (p<0.01) unidirectional decline of tumor endothelial permeability in all tumors under regorafenib treatment between baseline and follow-up as well as a non-uniform development of individual values with non-significant (p>0.05) changes of mean PS in the control group.…”

Image_1_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.TIF by Antonio G. Soares (11328795)

“…The GsD mouse also contains a cAMP response element-luciferase reporter transgene for non-invasive bioluminescence monitoring of cAMP signaling. …”

Image_1_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.TIF by Antonio G. Soares (11328795)

“…The GsD mouse also contains a cAMP response element-luciferase reporter transgene for non-invasive bioluminescence monitoring of cAMP signaling. …”