Showing 67,301 - 67,320 results of 125,061 for search '(( 5 ((026 decrease) OR (a decrease)) ) OR ( a ((point decrease) OR (mean decrease)) ))', query time: 1.99s Refine Results
  1. 67301
  2. 67302

    Table1_Safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of aficamten in healthy Chinese participants: a randomized, double-blind, placebo-c... by Xue Zhao (76712)

    Published 2023
    “…<p>Objectives: Aficamten is a selective, small-molecule allosteric inhibitor of cardiac sarcomere being developed as a chronic oral treatment for patients with symptomatic obstructive hypertrophic cardiomyopathy. …”
  3. 67303
  4. 67304

    Image_1_A Neonatal Murine Escherichia coli Sepsis Model Demonstrates That Adjunctive Pentoxifylline Enhances the Ratio of Anti- vs. Pro-inflammatory Cytokines in Blood and Organ Ti... by Esther M. Speer (5158913)

    Published 2020
    “…</p><p>Methods: Newborn C57BL/6J mice (< 24 h old) were injected intravenously with 10<sup>5</sup> colony forming units (CFUs)/g weight of a bioluminescent derivative of the encapsulated clinical isolate Escherichia coli O18:K1. …”
  5. 67305

    Data Sheet 1_Repair of spinal cord injury by bone marrow mesenchymal stem cell-derived exosomes: a systematic review and meta-analysis based on rat models.docx by Zhongduo Ye (19342831)

    Published 2024
    “…Additionally, BMSCs-Exo significantly reduced apoptosis levels (SMD = −4.52, 95% CI [−5.14, −3.89]), promoted the expression of axonal regeneration markers NeuN cells/field (SMD = 3.54, 95% CI [2.65, 4.42]), NF200 (SMD = 4.88, 95% CI [3.70, 6.05]), and the number of Nissl bodies (SMD = 1.89, 95% CI [1.13, 2.65]), and decreased the expression of astrogliosis marker GFAP (SMD = −5.15, 95% CI [−6.47, −3.82]). …”
  6. 67306

    Table_2_A Neonatal Murine Escherichia coli Sepsis Model Demonstrates That Adjunctive Pentoxifylline Enhances the Ratio of Anti- vs. Pro-inflammatory Cytokines in Blood and Organ Ti... by Esther M. Speer (5158913)

    Published 2020
    “…</p><p>Methods: Newborn C57BL/6J mice (< 24 h old) were injected intravenously with 10<sup>5</sup> colony forming units (CFUs)/g weight of a bioluminescent derivative of the encapsulated clinical isolate Escherichia coli O18:K1. …”
  7. 67307

    The effect of <i>N</i>-acetyl cysteine and doxycycline on TNF-α-Rel-a inflammatory pathway and downstream angiogenesis factors in the cornea of rats injured by 2-chloroethyl-ethyl... by Melad Sabzevare (11025491)

    Published 2021
    “…Rats were topically treated with a single and combined of 0.5% NAC and 12.5 μg/ml doxycycline and examined at 3rd, 15th, and 21st days. …”
  8. 67308
  9. 67309

    Table1_Hemolytic uremic syndrome in the setting of COVID-19 successfully treated with complement inhibition therapy: An instructive case report of a previously healthy toddler and... by Matija Matošević (14619110)

    Published 2023
    “…HUS was suspected, supported with compelling laboratory findings, including decreased platelets count and C3 levels, elevated LDH, urea, serum creatinine and sC5b-9 and presence of schistocytes in peripheral blood, negative fecal Shiga toxin and normal ADAMTS13 metalloprotease activity. …”
  10. 67310
  11. 67311
  12. 67312

    Table_1_A Neonatal Murine Escherichia coli Sepsis Model Demonstrates That Adjunctive Pentoxifylline Enhances the Ratio of Anti- vs. Pro-inflammatory Cytokines in Blood and Organ Ti... by Esther M. Speer (5158913)

    Published 2020
    “…</p><p>Methods: Newborn C57BL/6J mice (< 24 h old) were injected intravenously with 10<sup>5</sup> colony forming units (CFUs)/g weight of a bioluminescent derivative of the encapsulated clinical isolate Escherichia coli O18:K1. …”
  13. 67313

    Image1_Hemolytic uremic syndrome in the setting of COVID-19 successfully treated with complement inhibition therapy: An instructive case report of a previously healthy toddler and... by Matija Matošević (14619110)

    Published 2023
    “…HUS was suspected, supported with compelling laboratory findings, including decreased platelets count and C3 levels, elevated LDH, urea, serum creatinine and sC5b-9 and presence of schistocytes in peripheral blood, negative fecal Shiga toxin and normal ADAMTS13 metalloprotease activity. …”
  14. 67314

    Nox1*<sup>/Y</sup> mice have a greater percentage of CD127<sup>+</sup> NP-specific CD8<sup>+</sup> T cells at day 15. by Amelia R. Hofstetter (2512756)

    Published 2016
    “…CD127 and KLRG-1 staining was analyzed on D<sup>b</sup>-NP-IAV pentamer<sup>+</sup> cells among CD8<sup>+</sup> cells as demonstrated in the representative FACS dot plots taken from day 15 p.i. samples in A and B. Results in C-F plotted as individual mice with horizontal bar indicating mean. 2-way ANOVA indicates that the Nox1*<sup>/Y</sup> genotype contributes to increased lung CD127<sup>+</sup> cells (C, <i>p</i> < 0.001) and decreased double-negative CD127<sup>-</sup>KLRG-1<sup>-</sup> expressing cells (E, <i>p</i> < 0.0001; F, <i>p</i> < 0.05). …”
  15. 67315

    Glycoprotein YKL-40: A potential biomarker of disease activity in rheumatoid arthritis during intensive treatment with csDMARDs and infliximab. Evidence from the randomised control... by Tuija Väänänen (4392307)

    Published 2017
    “…<div><p>Objective</p><p>YKL-40, a chitinase-like glycoprotein associated with inflammation and tissue remodeling, is produced by joint tissues and recognized as a candidate auto-antigen in rheumatoid arthritis (RA). …”
  16. 67316

    Data_Sheet_1_Improvements in High-Density Lipoprotein Quantity and Quality Contribute to the Cardiovascular Benefits by Anti-tumor Necrosis Factor Therapies in Rheumatoid Arthritis... by Yonghong Luo (6111161)

    Published 2021
    “…Anti-TNF therapies were associated with significant increase in TC [mean difference (MD): +0.14, +0.23, and +0.26 mmol/l, respectively] and HDL (MD): +0.11, +0.12, and +0.11 mmol/l, respectively) in the short-, mid-, and long-term; anti-TNF therapies were associated with increased low-density lipoprotein (LDL) (MD: +0.06 mmol/l) and apolipoprotein A1 (ApoA1) (MD: +0.07 g/l) in the short-term, but not in the mid-term and long-term; triglyceride (TG) and apolipoprotein B (ApoB) do not change significantly in all the periods; proatherosclerotic indexes (TC/HDL, ApoB/ApoA1, and LDL/HDL) tend to decrease in the short- and mid-term, but return to baseline in the long-term after TNF inhibition.…”
  17. 67317

    Estimates and 95% confidence intervals from four models of the difference in household expenditure (USD) on mosquito-preventive products per risk perception group, COPA, 2018-2019<... by Josée M. Dussault (13155219)

    Published 2022
    “…The bands around each dot represents the 95% confidence intervals for each point estimate. Positive values indicate increased spending; negative values indicate decreased spending. …”
  18. 67318
  19. 67319

    Fluorescent intensity at 520 nm (RNase A/B) and 556 nm (DNase I) versus time for nucleases in DI water lysed with Lyse-It at 30% and 50% power for varying time. by Tonya M. Santaus (5559077)

    Published 2019
    “…<p><i>Pre</i> is the nuclease suspension without microwave irradiation. <b>(A)</b> 20 pM RNase A <b>(B)</b> 46 pM RNase B, <b>(C)</b> 10.5 nM DNase I. …”
  20. 67320