Establishment of Replicating Mycobacterium tuberculosis in an Aerosol Mouse Model of Infection: Active vs. Chronic Infection by Larry Bowen (5750969)

“…Mice in the treatment groups were administered INH daily from Day 20 through Day 40 at a dose concentration of 25 mg/kg/day. Subsets of mice (5/time point) in this group were euthanized on Days 20, 30, 40, 50 and 60. …”

TGF-β1-induced suppression of COX-2 expression by transcriptional repression. by Erina Takai (465811)

“…<p>(A) Time-dependent decrease of COX-2 mRNA expression by treatment with TGF-β1 (5 ng/mL). …”

DELTA-1/NOTCH signaling in the caudal spinal cord of chick embryos. by Barbara Hämmerle (36261)

“…In contrast, control pCIG transfected cells do not altere <i>Hes5.1</i> expression (E–E′). F–F′. Confocal projection over 50 µm taken from a dorsal view point of the prospective spinal cord at the level of the 12th–14^th somites counted from rostral of an embryo which was electroporated with the antisense morpholino oligo Mo2-cDelta1 at HH10 stage and allowed to develop until HH12/13. …”

Normalized fluorescence of calcium indicator Fluo-4 after laser perforation. by Stefan Kalies (388164)

“…The mean and standard error of three experiments with five irradiated and analyzed cells are shown.…”

Effects of RhoB in invasion and migration of 786-O cells. by Weihao Chen (431221)

“…<p>The invasion (<b>A</b>) and migration (<b>B</b>) of 786-O cells transfected with pcDNA3.0-Flag-RhoB decreased nearly 4.59-fold (for invasion) and 5-fold (for migration) after transfection with pc-DNA3.0-Flag-RhoB compared with the empty vector. …”

Characterization of changes in Ecrg4 gene expression in ME mucosal after NTHi infection. by Arwa Kurabi (344167)

“…<p><b>Panel A:</b> Mining a genechip microarray showed time-dependent decreased Ecrg4 expression levels after NTHi infection (solid line) of mouse ME. …”

Time to Definitive Health-Related Quality of Life Score Deterioration in Patients with Resectable Metastatic Colorectal Cancer Treated with FOLFOX4 versus Sequential Dose-Dense FOL... by Zeinab Hamidou (563982)

“…The TUDD was defined as the time interval between randomization and the first decrease in HRQoL score ≥ 5-point with no further improvement in HRQoL score ≥ 5 points or any further HRQoL data. …”

Comparison between the Uncoiling/Coiling Forces of the Fimbrial Shaft versus the Lifetime of the FimH–Mannose Bond by Manu Forero (65268)

“…The solid triangles (left axis) show the fraction of FimH–1M bonds that last longer than 1 s in flow chamber experiments (<i>n</i> = 4 to 6 for each point). These experiments are described in detail in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0040298#pbio-0040298-g005" target="_blank">Figure 5</a>. …”

Impact of exercise initiation at 18-months-old on aging-related motor decline. by Jennifer C. Arnold (4621795)

“…Aging produced a significant decrease in movement number (F_(5,90) = 18.67, <i>p<</i>0.0001). …”

The average time cost and accuracy of the assessed secondary structure prediction methods as the target dataset size reduces. by Sheng-Hung Juan (9046515)

“…The meanings of the axes of this plot are the same as those of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.g001" target="_blank">Fig 1</a>, but the scale of the vertical axis of accuracy (blue) is adjusted to start from 0.5 to make visible the standard deviations, which were obtained by ten repeats of random sampling test for each assessed method. …”

CHOP knockdown inhibits the induction of PUMA and BIM in neuronal cells in response to ER stress. by Arindam P. Ghosh (317870)

“…<p>(A) Knockdown of CHOP in SH-SY5Y cells using shRNA ameliorated the induction of PUMA with tunicamycin in comparison to control cells. …”

Frequency dependent increase in contractile response of isolated detrusor strips in response to trains of 20 pulses at frequencies ranging from 0.25 to 40 Hz in the absence or in t... by Sara Pritchard (4030679)

“…Each data point represents mean ± sem (n = 5) * P<0.05.</p>…”

Fluoride exposure and its interaction with <i>ATP2B1</i> polymorphism in the alteration of lipid metabolism in adults by Junhua Wu (154979)

“…Rs12817819 with carriers of T allele was associated with the decrease in serum ApoA1 (OR = 0.46 [95% CI, 0.26–0.81]), but inversely in rs17249754 with carriers for A allele (OR = 1.48 [95% CI, 1.07–2.06]) and rs7136259 with carriers for T allele (OR = 1.70 [95% CI, 1.22–2.37]). …”

RO5464466 blocked the production of progeny virus and inhibited an established influenza virus infection. by Lei Zhu (16642)

“…<p>(A) Decrease of progeny virus production in cells treated with RO5464466 and other reference compounds. 12-well plates were seeded with MDCK cells at a density of 1.5×10⁵ cells per well. …”

Measure nicotine dependence by the fagerström test for nicotine dependence by Caroline Francieli WEBER (4772265)

“…The degree of nicotine dependence was classified, by the mean, 4.45 ± 2.53 points (±SD). There was a significant correlation between nicotine dependence and the number of cigarettes smoked per day. …”

NO is involved in the mediation of the suppressive effect of capsaicin on LA-LTP. by Carsten Zschenderlein (357561)

“…(D) Bar histogram of data points averaged 57 to 60 min after HFS and normalized with respect to baseline (mean ± SEM). …”

Nicotinic receptor inhibition reduces ethanol-induced increases in duodenal bicarbonate secretion. by Anna Sommansson (599993)

“…The values are the mean ± SEM; 15% ethanol (n = 11), hexamethonium alone (n = 4), and 15% ethanol + hexamethonium (n = 9). * indicates a significant (p<0.05) increase compared with baseline in the same group, # indicates a significant decrease compared with baseline in the same group and § indicates a significantly lower value compared with the corresponding time point in the ethanol 15% group of animals.…”

Ovariectomy (OVX) induced decline in brain glucose uptake and BBB GLUT1_{55 Kda} expression: prevention by 17β-estradiol. by Fan Ding (302565)

“…Quantitative analysis of brain glucose uptake demonstrated a significant decrease in OVX condition (**, p<0.01, bars represent mean value±SEM, n = 5–7), which was partially prevented by E2 treatment (50 µg/kg, SC) (*, p<0.05; bars represent mean value±SEM, n = 5–6). …”

Analysis of cell periods. by Tanya L. Leise (174630)

“…Thick bars designate times when the luminescence for a cell was above the mean for each row. Cell #66 with period 25.5 h is plotted in red; cell #68 with period 22.5 h is plotted in blue. …”

Data_Sheet_1_Prospective cohort study evaluating efficacy and safety of efgartigimod in Chinese generalized myasthenia gravis patients.docx by Pan Wang (198097)

“…The most significant reduction in quantitative MG (QMG) scores also occurred at week 4, with a mean decrease of 7 points. Notably, the improvements in MG-ADL and QMG scores persisted until week 8. …”