Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells and in xenografts: Identification of apoptotic genes as targets for demethylation-1 by Khaldoun Al-Romaih (79731)

“…</p><p></p>ice (panel B) using immunohistochemical staining with 5-mc-Ab. To the right a 20X enlargement of representative U2OS histology is shown. …”

Knockdown of <i>Adamts19</i> in XX gonads and <i>Ctrb1</i> in XY gonads. by Kathryn S. McClelland (687254)

“…Knockdown of ADAMTS19 in the XX gonad (n = 7, 8, 5, 5) showed no change in female somatic markers <i>Fst</i> (B) and <i>Irx3</i> (C) and a slight decrease in expression of germ cell marker <i>Ddx4</i> (D). …”

Multiplex Detection of Homo- and Heterodimerization of G Protein-Coupled Receptors by Proximity Biotinylation by Elisabeth Steel (545397)

“…As a test case for our newly developed assay, we have characterized the homo-dimerization of chemokine receptor CXCR4 and heterodimerization of CXCR4 with CCR2 or CCR5. …”

<b>Attenuation of an original novel goose parvovirus strain NMG21 via serial cell passage</b> by Dalin He (13763531)

“…Increased virus <a href="" target="_blank">titer</a> was observed at the 5th passage (P5). …”

Blood pressure effects of ephedrine treatment. by Daniel Radiloff (588253)

“…Tissue hypoxia was measured by pO₂ needle electrode tracings during inspired normoxia (1) and hypoxia at baseline (2), before (3) and after injection under normoxia (4), and during post-injection hypoxia (5). D: under post-treatment normoxia (panel D time point #4), ephedrine alone and in combination with ambrisentan significantly increased muscle oxygenation, compared to pre-treatment pO₂ (one-way ANOVA with Bonferroni correction, N = 4–8, p<0.05). …”

The combination of discontinuous dexamethasone and PEGylated asparaginase shows synergistic efficacy in bone marrow. by Seth E. Karol (780961)

The thermo-mechanical response of PP nanocomposites at high graphene loading by Kai Yang (73590)

Data_Sheet_1_PCSK9 inhibitor in acute ischemic stroke patient receiving mechanical thrombectomy: early outcomes and safety.docx by Jonguk Kim (632752)

“…Background<p>Lipid-lowering therapies are mainstays in reducing recurrence after acute ischemic stroke (AIS). Evolocumab, a Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitor, is a promising lipid-lowering agent known to decrease LDL cholesterol and mitigate vascular events alongside statins. …”

Data_Sheet_1_Visualizing and Quantifying Irregular Heart Rate Irregularities to Identify Atrial Fibrillation Events.pdf by Noam Keidar (5896064)

“…Based on the variability and normality indices calculated for long 1-lead ECG records, we created a plot termed a regularogram (RGG), which provides a visual presentation of irregularly irregular rates and their burden in a given record. …”

Intact Polar Lipids. by B. Jacob Kendrick (662898)

“…Chloroplast lipids such as MGDG (yellow slices), DGDG (blue slices), and SQDG (pink slices) decrease dramatically in 18V as photosynthetic efficiency decreases. 18V also demonstrates a significant decrease in diacylglycerylcarboxy-N-hydroxymethyl-choline (DGCC, dark green slices) which is involved in fatty acid transport into the MGDG synthesis pathway. …”

<i>C6ST</i>-1 mRNA or 6-sulphated GAGs were not expressed in <i>C6ST</i>-1 KO mice. by Rachel Lin (215087)

“…The amplification of housekeeping Hprt acts as a positive control. (b) FACE gel showed a decrease of 6-sulphated GAGs in <i>C6ST</i>-1 KO animals compared to WT mice (lanes marked with “−”). …”

Enhanced proteoglycan accumulation in articular cartilage of CCN2 transgenic mice. by Shinsuke Itoh (125939)

“…The content of TB metachromasia-positive proteoglycans decreased with aging; however, TG articular cartilage showed a greater accumulation of proteoglycans than did the cartilage of WT littermates at all time points. …”

Inhibition of Aurora kinases by MLN8237 impairs germinative cell maintenance and larval growth of <i>E. multilocularis</i>. by Zhe Cheng (397373)

“…(B) Quantification of the multinucleated cells and EdU⁺ cells in the vesicles treated with 5 μM of MLN8237 for 6 days and 14 days. Data indicate the number of each type of cells per 1000 total cells and are shown as mean ± SD of three separate experiments. …”

Data_Sheet_1_Biochemical Composition and Energy Strategy Along the Reproductive Cycle of Female Octopus vulgaris in Galician Waters (NW Spain).PDF by Pilar Sieiro (9122633)

“…Additionally, the most abundant fatty acids (FA) in all tissues were 16:0, 18:0, 20:1n9, 20:4n6 (ARA), 20:5n3 (EPA) and 22:6n3 (DHA), with a clear predominance of long-chain polyunsaturated FA. …”

DataSheet_1_Loss of Cadherin-11 in pancreatic ductal adenocarcinoma alters tumor-immune microenvironment.pdf by Aimy Sebastian (823355)

“…We also observed a significant decrease in the presence of monocytes/macrophages and neutrophils in KPC-Cdh11^+/- tumors while the proportion of T cells was increased. …”

Difference in GHG emissions (<em>x</em>-axis) and food availability (<em>y</em>-axis) in 2050 for the different scenarios with respect to 'TREND' by H Valin (557174)

“…Panels (A)–(C) and (D) delineate domains where food provision increases ((A), (B)) or decreases ((C), (D)) and GHG emission savings increase ((B), (D)) or decrease ((A), (C)). …”

Kinetics of YFP induction in fry. by Alexander Froschauer (765700)

“…(D) Fluorescence values (area fluorescence, arbitrary units) after treatment of fry with the indicated concentrations of Shield-1. Data points of three individuals are shown for the vehicle control, 5–6 individuals for the other groups (mean with standard deviation). …”

Performance in the Forced Swim Test (FST). by Daniel Van den Hove (209845)

“…<p>Distance swum in the FST (5-minute period) was significantly decreased in prenatally stressed (PS) versus control (C) animals (P = 0.037). …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

“…<i>P</i> < 0.05, |log₂ fc| > log₂ (1.5)] modulated ones are indicated with name. Niraparib decreases CYP51A1 (lanosterol 14α-demethylase) enzyme levels (Supplementary Fig. …”

Binding energy differences for the orthogonal interface redesign task. by Andrew Leaver-Fay (214911)

“…<p>Binding energy differences between the positive state AB (Ral/RalBP1) and negative states AC (RalA/Sec5) and AD(RalA/Exo84) following multistate design (MSD) and single state design (SSD). …”