Schematic representation of identification and selection of top hits that inhibit viral M mRNA nuclear export and/or expression. by Matthew Esparza (8661219)

“…The top 600 compounds from single-dose confirmation studies were further evaluated in a 12-point dose response study to assess the potency (AC50 –concentration at 50% activity). …”

Data_Sheet_1_An economic analysis of high milk somatic cell counts in dairy cattle in Chiang Mai, Thailand.docx by Tosapol Dejyong (14055744)

“…Dairy cooperatives point at high-SCC problems as an important factor leading to suboptimal levels of milk quantity and quality. …”

Table 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.docx by Chengzhi Hou (20419865)

“…To the left of this inflection, each unit increase in ALI was associated with a 1.3% decrease in all-cause and cardiovascular mortality risk among MACCE patients. …”

Transcriptome Profiling of the Intoxication Response of <em>Tenebrio molitor</em> Larvae to <em>Bacillus thuringiensis</em> Cry3Aa Protoxin by Brenda Oppert (168488)

“…<div><p><em>Bacillus thuringiensis</em> (Bt) crystal (Cry) proteins are effective against a select number of insect pests, but improvements are needed to increase efficacy and decrease time to mortality for coleopteran pests. …”

Image 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.tif by Chengzhi Hou (20419865)

“…To the left of this inflection, each unit increase in ALI was associated with a 1.3% decrease in all-cause and cardiovascular mortality risk among MACCE patients. …”

Successful Application of Adaptive Emotion Regulation Skills Predicts the Subsequent Reduction of Depressive Symptom Severity but neither the Reduction of Anxiety nor the Reduction... by Carolin M. Wirtz (647287)

“…</p><p>Results</p><p>Successful ER skills application was cross-sectionally associated with lower levels of DSS, ASS, and GDS at all points of assessment. An increase in successful skills application during treatment was associated with a decrease in DSS and GDS but not ASS. …”

DataSheet1_Building Structure-Property Relationships of Cycloalkanes in Support of Their Use in Sustainable Aviation Fuels.docx by Alexander Landera (1958899)

“…Recently, cycloalkanes have been shown to exhibit some o-ring swelling behavior, possibly making them an attractive substitute to decrease the aromatic content of aviation fuel. Cycloalkanes must meet specifications for a number of other physical properties to be compatible with jet fuel, and these properties can vary greatly with the cycloalkane chemical structure, making their selection difficult. …”

RenTg mice are hypertensive and develop chronic kidney disease progressively with the age. by Anne-Cecile Huby (291994)

“…<p>Systolic blood pressure was highly increased in RenTg mice since the age of 3 months as compared to aged matched WT controls (A). Urinary excretion of albumin progressively increased with age to reach at 12 months highly elevated values in RenTg mice (B) whereas GFR significantly decreased (C). …”

Worm infestations and development of autoimmunity in children – The ABIS study by Johnny Ludvigsson (167260)

“…At 8 years in total 20.0% of the general child population had experienced a worm infestation; children who developed Type 1 diabetes, 21,3%, celiac disease 19,5% and JRA 18,8%. …”

Wind-Driven Ignition Behavior of Wildland Fuels: Experimental Insights Under Controlled Conditions by Shusmita Saha (19162790)

“…For example, in wheatgrass fuels, flaming ignition temperature rose from ~ 472°C to ~ 610°C as wind speed increased from 0.5 to 2.0 m/s, with a concurrent decrease in smoldering-to-flaming transition time from 105 to 61 seconds. …”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

SLS-4 is required for the <i>in vitro</i> ubiquitination of poly-SUMO-2 chains and degradation of SUMO conjugates <i>in vivo</i>. by Chris Boutell (205885)

“…<p>(A) <i>In vitro</i> ubiquitination reactions were carried out in the presence of E1, UbcH5a and ubiquitin (Ubmix), poly-SUMO-2 chains and purified wt ICP0, ICP0ΔRING, or ICP0 C-terminal truncation mutants ICP01-323, ICP01-396 or ICP01-396mSLS-4 as indicated (-/+). …”

Impact of loss of <i>Hes1</i> on differentiation and proliferation in the second heart field. by Francesca Rochais (371680)

“…<p>(A) Immunochemistry with anti-MHC (left), anti-α-actinin (right) and anti-β-galactosidase antibodies in transverse sections through the caudal pharyngeal region of an E9.5 embryo carrying the <i>Mlc1v-nlacZ-24</i> transgene. …”

Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin by Tiago Nicoliche (8566002)

“…Based on the results of this study, the curcumin treatment appeared to exert a protective effect on cartilage, as it did not result in an increase in cartilage thickness or in MMP-8 and MMP-13 expression but led to increased IHH, Col2, and SOX-5 expression and the number of chondrocytes.…”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

HSPs Inhibits CKII Mediated TDP-43 Filament Assembly. by Yari Carlomagno (152800)

“…<p>Hsp90 can inhibit the polymerization of tau, and TDP-43 is a known substrate for Hsp90. To examine the effects of Hsp90 on CKII mediated rTDP-43 filament assembly, 2.5 µM TDP-43 was polymerized for 60 minutes with CKII in the presence of 0.0–2.5 µM Hsp90. …”

Evaluation of Tetrahydrobiopterin Therapy with Large Neutral Amino Acid Supplementation in Phenylketonuria: Effects on Potential Peripheral Biomarkers, Melatonin and Dopamine, for... by Shoji Yano (2937894)

“…<p><b>Overnight serum melatonin AUC (A) and Plasma phenylalanine concentrations (B) over the 4 phases.…”

HIV-1 p17 oligomerization in solution depends on ionic strength. by Cinzia Giagulli (354803)

“…The detection of an approximately 40.000 Dalton band (trimeric p17) increases with the decreasing of NaCl concentration (lane A: p17 in NaCl 0.5 M; lane B: p17 in NaCl 0.2 M; lane C: p17 in NaCl 0.1 M), while p17 is mostly in a monomeric form in a solution containing 0.5 M NaCl. …”

<i>daf-12/NHR</i> and <i>daf-16/FOXO</i> have distinct effects in <i>germ cell (−)</i> animals. by Tracy M. Yamawaki (242774)

“…Means and <i>p</i> values are listed in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000468#pbio.1000468.s008" target="_blank">Table S6</a>. …”

E610G variant accounts for <i>Modifier-of-vibrator</i> activity of <i>Nxf1</i>. by Dorothy Concepcion (264617)

“…<p><b>(A)</b> The E610G edited allele decreased tremor severity. …”