Cohort cholecystectomies in the Brazilian public system: is access to laparoscopy universal after three decades? by JOSÉ GUSTAVO OLIJNYK (13106046)

“…Results: the LC rate reached 41.5% (growth of 68%) with no decrease in the absolute number of OC. …”

Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2‑Thiohydantoin Compounds by Fangrui Wu (1434937)

Voluntary Exercise Prevents Cisplatin-Induced Muscle Wasting during Chemotherapy in Mice by Pernille Hojman (61813)

“…Cisplatin treatment induced loss of body weight (29.8%, P<0.001), lean body mass (20.6%, P = 0.001), as well as anorexia, impaired muscle strength (22.5% decrease, P<0.001) and decreased glucose tolerance. …”

<i>Eugenia uniflora L.</i> seed and pulp extracts: phytochemical profile, cytotoxic potential, antitumoral activity, and α-amylase and α-glucosidase inhibition capacity by Felipe Tecchio Borsoi (12423536)

“…The extracts were obtained using a cellulase complex and the phenolic compounds were quantified. …”

³H-BaP cellular protein adducts after DMSO, BSO or BaP. by B. Alex Merrick (15133)

“…<p>T47D cells were pretreated for 48 hr with 0.5 mM BSO or 4 µM BaP (unlabeled) to decrease or increase GSH compared to DMSO control (0.4 v/v). …”

Timing of thyroid ultrasonography in the etiological investigation of congenital hypothyroidism by Maria de Fátima Borges (4628215)

“…Comparisons with previous T-US showed concordant results regarding thyroid location, but a decrease in current volume was observed in eight due to the use of L-thyroxine, calling the diagnosis of hypoplasia into question. …”

Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition by Andrea Cippitelli (194306)

“…In the present study, we hypothesized that spontaneous withdrawal resulting from removal of chronically implanted transdermal nicotine patches is regulated by the endocannabinoid system. A 7-day nicotine dependence procedure (5.2 mg/rat/day) elicited occurrence of reliable nicotine abstinence symptoms in Wistar rats. …”

The TrkB was expressed in neurons in the injured brain and treatment with 7,8-dihydroxyflavone attenuated stretch-induced cytotoxicity and apoptosis in primary cultured neurons. by Chun-Hu Wu (306057)

“…<b>(E)</b> Western blot analysis of apoptosis-related proteins (cleaved caspase-3, Bcl-2, and Bax) shows that 5 µM DHF significantly decreased the cleaved caspase-3 level and the Bcl2/Bax ratio. …”

Fig 4 - by Albert J. Bae (14773952)

“…At a fixed value of the static curvature, <i>C</i>₀ = 0.2, the mean rotational velocity decreases as the amplitude of dynamic mode <i>C</i>₁ decreases from G) <i>C</i>₁ = 0.7, to H) <i>C</i>₁ = 0.5 and further to I) <i>C</i>₁ = 0.2.…”

Metabolic scheme to the impact of extracellular pyruvate on the metabolic conversion rates measured in the culture medium supernatants as well as on the intracellular concentration... by Floriana Jessica Di Paola (18982191)

“…The intracellular concentrations of glutamate itself and proline, which is synthesized from glutamate and the essential amino acids methionine and leucine and semi essential amino acid tyrosine decreased in pyruvate-high cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0325509#pone.0325509.s011" target="_blank">S3 Table</a>).…”

Impact of frame shifts on tracking model performance. by Owen M. O’Connor (11965460)

“…<p>The average prediction in the four cardinal directions to ground truth overlap for 20 representative tracking events plotted as a function of the shift distance. Tracking model performance when <b>(A)</b> cell density is low (<5 cells in the frame), <b>(B)</b> medium (20–25 cells in the frame), or <b>(C)</b> high (>200 cells in the frame). …”

Oxidation of surface carbohydrates increases CCL28 binding. by David L. Erickson (30603)

“…<i>pseudotuberculosis</i> IP32953 is enhanced by treatment with sodium periodate in a dose-dependent fashion. The binding levels are expressed as the mean (±SD) relative to the 80 mM samples. …”

Table_1_Environmental, behavioral, and design-related factors affect accuracy and precision of beluga abundance estimates from aerial surveys.docx by Véronique Lesage (242785)

“…Simulation-based power analysis indicates a large benefit associated with conducting more than 1 or 2 survey reps, but a declining benefit of conducting > 5—10 survey reps. …”

The computational model can explain impaired glucose homeostasis and β-cell dysfunction under varying glycemic conditions in HepaRG liver-islet MPS. by Belén Casas (5906522)

“…Model uncertainty is depicted as shaded areas in panels <b>A-E</b>. Data in panels <b>A-B</b> are presented as mean ± SEM, n = 5. n: Number of platform replicates included in the experiment.…”

Epigenetic regulation of EndMT mediated by loss of ERG/FLI1. by Nao Nagai (6034187)

“…The regions where the H3K27Ac level is significantly decreased after siERG+siFLI1 treatment are marked with a dagger (†). …”

Inhibition of PI3K/Akt activity reduces phosphorylation of GSK3β while increases HB9 motor neuron differentiation. by Luis Ojeda (208583)

“…In both ELL and FL primed groups, all inhibitors decreased GSK3β Ser9 phosphorylation as compared with DMSO controls (mean ± SEM; n = 3; * p<0.05, ** p<0.01, *** p<0.001, one-way ANOVA). …”

DataSheet_1_Thalamocortical Hyperconnectivity and Amygdala-Cortical Hypoconnectivity in Male Patients With Autism Spectrum Disorder.doc by Tetsuya Iidaka (162492)

“…</p><p>Methods: To overcome this issue, we analyzed multisite neuroimaging data from a large sample (n = 626) of male participants aged between 5 and 29 years (mean age = 13 years). …”

Testing the “Read-across hypothesis” by investigating the effects of ibuprofen on fish. by Alpa Patel (2937030)

“…Results showed that PGEM levels in fish exposed to 370 and 470 µg ibuprofen/L were significantly decreased compared to control fish, when mean plasma ibuprofen concentrations were 1.8 to 5.6-fold below the C_max. …”

DataSheet_1_Thalamocortical Hyperconnectivity and Amygdala-Cortical Hypoconnectivity in Male Patients With Autism Spectrum Disorder.doc by Tetsuya Iidaka (162492)

“…</p><p>Methods: To overcome this issue, we analyzed multisite neuroimaging data from a large sample (n = 626) of male participants aged between 5 and 29 years (mean age = 13 years). …”

siRNA-mediated knockdown of selected IGCs impairs GSC viability. by Julia Pollak (234075)

“…CellTiter-Glo viability assay 72 hours following siRNA-mediated knockdown of IGCs. GSC viability decreased in response to increasing amounts of siRNA (2, 5, and 20 pmol). …”