Defective cellular signalling in <i>Cdkl5</i> knockout mice. by Elena Amendola (565348)

“…(<b>C</b>) Western blot quantification revealed a significant decrease in phospho-Akt immunoreactivity protein in mutant <i>Cdkl5</i> mice compared with wild-type controls (female: WT, N = 10, HET, N = 6, KO, N = 10; male: WT, N = 5, KO, N = 6; mean ± SEM) (mean ± SEM; *P<0.05, **P<0.01). …”

UPR gene and protein expression of autoimmune hepatitis (AIH) livers compared to pediatric normal controls (pNormal) and pediatric cholestatic liver disease (pCLD) samples. by Alyssa Kriegermeier (4707226)

“…<p>A) Using qPCR, we determine that: compared to AIH livers (n = 5), pCLD livers (n = 10) had decreased expression of IRE1α, XBP1s, and EDEM1 by 78%, 77%, and 67% while ERdj4 gene expression was similar. …”

Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug–Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection by Zilin Zhang (4370773)

“…Monodispersed sirolimus (SRL)-loaded poly­(lactic-<i>co</i>-glycolic acid) microspheres with a diameter of 1.8, 3.8, and 8.5 μm were produced by high-throughput microfluidic step emulsificationsolvent evaporation using single crystal silicon chips consisted of 540–1710 terraced microchannels with a depth of 2, 4, or 5 μm arranged in 10 parallel arrays. …”

Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug–Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection by Zilin Zhang (4370773)

“…Monodispersed sirolimus (SRL)-loaded poly­(lactic-<i>co</i>-glycolic acid) microspheres with a diameter of 1.8, 3.8, and 8.5 μm were produced by high-throughput microfluidic step emulsificationsolvent evaporation using single crystal silicon chips consisted of 540–1710 terraced microchannels with a depth of 2, 4, or 5 μm arranged in 10 parallel arrays. …”

Cytokines and chemokines in lung tissue after sham procedure or double hit (DH) in wild type (wt) mice (black bars) or in absence of C5 (C5^-/-) mice (grey bars). Systemi... by Miriam Kalbitz (3150195)

“…<p><b>A</b>. Increased IL-6 levels in lung tissue of wt and in C5^-/- mice after DH compared to sham. …”

Information on the extracted dataset. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Based on flow cytometry analysis with the propidium iodide the irradiated (9h after IR) hiPSC-DCHs and mature chondrocytes pointed at accumulation and cell cycle arrest in G2 phase... by Ewelina Stelcer (5334791)

“…<p>In turn, hiPSCs exposed to IR demonstrated high level of cells found in S phase (A). All investigated cells (hiPSCs, hiPSC-DCHs and chondrocytes) showed little differences in ROS level measured–using CellROX Green Reagent and tert-butyl hydroperoxide as a positive control- immediately after IR. …”

Irradiated <i>fog-2</i> germlines exhibit high internuclear variance in DSB repair following irradiation. by Erik Toraason (5724689)

O-GlcNAcylation and ubiquitination of A20 modulate its expression. by Gautam V. Shrikhande (227350)

“…(F) WB analysis of total and phospho-A20 in SMC cultured in 5, 15 and 30 mM D-Glu and treated with TNF for 6 h demonstrated that relative phosphorylation levels of A20 (pA20) were not decreased by high glucose, despite decreased TNF-mediated upregulation of A20 protein in cells cultured in high glucose. …”

Astilbin treatment decreases the percentage of CD44^hiCD62L^lo activated CD4⁺ T cells and several cytokine mRNA expression. by Lele Guo (720961)

Improved YOLOv8 network architecture. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Comparison of the three attention steps. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Hardware platform and environment parameters. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

EfficientRepBiPAN network structure. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Cattle image labeling. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Standard YOLOv8 network structure. by Enming Zhao (3957782)

“…Through comparative evaluations with heatmap and regression-based models such as HRNet, HigherHRNet, DEKR, DEKRv2, and YOLOv5-pose, our method improves AP_0.5 by at least 0.4%, reduces the number of parameters by at least 0.4%, and decreases the amount of computation by at least 1.0 GFLOPs, achieving a harmonious balance between accuracy and efficiency. …”

Cilostazol inhibits endothelin-induced calcium increase and vasoconstriction in mouse intracranial arteries. a. by Yoshifumi Kawanabe (308848)

“…</b> Cilostazol significantly decreases endothelin-induced cytosolic calcium increase. …”

Association of Hypoxia-Inducible Factor-2 Alpha Gene Polymorphisms with the Risk of Hepatitis B Virus-Related Liver Disease in Guangxi Chinese: A Case-Control Study by Liling Huang (1627294)

“…However, in subgroup analysis by gender, the HIF-2a rs13419896 GA and AA genotypes were significantly associated with a risk of CHB (odds ratio [OR] = 3.565, 95% confidence interval [CI] = 1.123–11.314, <i>p</i> = 0.031 and OR = 12.506, 95% CI = 1.329–117.716, <i>p</i> = 0.027) in females, and the A allele of rs13419896 was associated with a risk of CHB (OR = 2.624, 95% CI = 1.244–5.537, <i>p</i> = 0.011) and LC (OR = 2.351, 95% CI = 1.002–5.518, <i>p</i> = 0.050) in females. …”

Changes in IL-6 levels during uric acid or rasburicase infusion and oral lipid tolerance test pre- and post- intervention. by Toshiko Tanaka (174638)

DataSheet3_Dietary sodium enhances the expression of SLC4 family transporters, IRBIT, L-IRBIT, and PP1 in rat kidney: Insights into the molecular mechanism for renal sodium handlin... by Lu Cai (158735)

“…Bicarbonate transporters NBCn1, NBCn2, and AE2 are expressed at the basolateral membrane of the medullary thick ascending limb (mTAL). In a previous study, NBCn1, NBCn2, and AE2 are proposed to play as a regulatory pathway to decrease NaCl reabsorption in the mTAL under high salt condition. …”