Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1 by Goichi Beck (818821)

“…The present study aimed to clarify the mechanism underlying brain iron accumulation during the deficiency of calcium-independent phospholipase A2 beta (iPLA₂β), which is encoded by the <i>PLA2G6</i> gene. …”

Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model by Donald W. Lawrence (4923328)

“…Here, we present novel data describing a role for NKLAM in regulating the immune response to Sendai virus (SeV), a murine model of paramyxoviral pneumonia. …”

Hypocotyl and cotyledon phenotypes of plants expressing SAUR63:X fusion proteins. by Punita Nagpal (185838)

Qualitative summary of trends observed in this study, relating catchment size and viral prevalence to (a) the extent to which near-source wastewater surveillance revealed locally-s... by Jay C. Bullen (10232606)

<i>Drosophila</i> Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling by Einat Cinnamon (2922108)

“…Several enzymes of fatty acid, triglyceride and hydrocarbon metabolism are required in oenocytes primarily for lipid droplet induction rather than for cell growth. In contrast, a very long chain fatty-acyl-CoA reductase (FarO) and a putative lipid dehydrogenase/reductase (Spidey, also known as Kar) not only promote lipid droplet induction but also inhibit oenocyte growth. …”

KIF4 knockdown blocks HBV entry and HDV infection into host cells. by Sameh A. Gad (12269979)

Noise-induced transition to bistable behaviour. by Tomás Alarcón (224873)

Several human uORFs have repressive terminal diproline motifs. by Ty A. Bottorff (14035065)

<i>In planta</i> experiments on two different tomato plant cultivars. by Set Madian Perez (6786653)

Effects of the SMS program on the mini-HEI and on the BMI z-scores. by Anne Ahrendt Bjerregaard (7377500)

Effects of the SMS program on intake of SSBs, intake of FV, and intake of fish. by Anne Ahrendt Bjerregaard (7377500)

GOVERNMENT CORRUPTION ON BRAZILIAN CAPITAL MARKETS: A STUDY ON LAVA JATO (CAR WASH) INVESTIGATION by ANA JULIA AKAISHI PADULA (5717405)

“…The results indicate that there was a significant devaluation of the largest state-owned companies traded on the Brazilian Stock Exchange and in American Depository Receipts, leading to money laundering and a decrease in economic growth. …”

Inhibition of transcription impacts E2-induced enhancer-promoter spatial separation, but not chromosome conformation capture contact frequencies. by Luciana I. Gómez Acuña (18605719)

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes by John R. Cashman (354526)

“…Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (I_NaL) SCN5A mutations that prolongs cardiac action potential (AP) and enhances I_NaL current. …”

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells by David A. Tumbarello (680437)

“…Conversely, overexpression of SPARC increased TGFBI deposition. A SPARC-YFP fusion construct expressed by the Met5a cell line co-localized with TGFBI in the cell-derived ECM. …”

Changes to the distance between the human cytomegaloviral uORF2 start codon and the elongating ribosome stall do not change repressiveness or buffering, consistent with the collisi... by Ty A. Bottorff (14035065)

Constitutive Expression of Yes-Associated Protein (Yap) in Adult Skeletal Muscle Fibres Induces Muscle Atrophy and Myopathy by Robert N. Judson (394940)

“…Unexpectedly, after 5–7 weeks of constitutive hYAP1 S127A over expression, mice suddenly and rapidly lost 20–25% body weight and suffered from gait impairments and kyphosis. …”

Bexarotene pretreatment significantly suppressed HBV and HDV infections in primary human hepatocytes (PHH). by Sameh A. Gad (12269979)

Comparison of Ten Top-ranked Gene Ontology (GO) Categories Significantly Over-Represented in the Two Subsets (1,709 Decreased, Upper Panel; 903 Elevated, Lower Panel) of NOA-relate... by Hiroyuki Okada (40310)

“…<i>p</i>-Values were determined by Fisher's exact test using all of the GO-annotated genes on the Agilent Human 1A(v2) microarray as a background, as shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040026#pgen-0040026-t001" target="_blank">Table 1</a>. …”

Predictive values of IC₅₀ in mM (FFAs) for vanadium compounds and <i>in vivo</i> observations IC₅₀ in mM (FFAs) and decreasing blood glucose level. by Elena V. Fedorova (603922)