Isomorphous Substitutions of Rare Earth Elements for Calcium in Synthetic Hydroxyapatites by Lyudmyla I. Ardanova (2252215)

Suppressing endogenous EB1 and KIF3A reduces the dynamics of YFP-Kv1.2 puncta. by Yuanzheng Gu (244592)

“…Hippocampal neurons co-transfected at 4 DIV with YFP-Kv1.2, Kvβ2, and siRNA plasmids against either EB1 (B) or KIF3A (C) were fixed and stained 4–5 days later. Reduction of either EB1 (B) or KIF3A (C) decreased the axonal level of YFP-Kv1.2. …”

A 1:2000 scale map of the 2.12 km² study area: The UC Santa Cruz campus. by Ishana Shukla (20189612)

<i>Rabx-5</i> mutant animals have aberrant synaptic vesicles. by Sharon B. Sann (320476)

“…<p>A) P_unc-25Synaptobrevin::GFP intensity is increased in soma and synaptic regions in <i>rabx-5</i> mutant animals. …”

Impact of miRNA function on HCV replication in Huh7.5 cells. by Xiaozhen Zhang (281572)

“…A Mann-Whitney test of multiple comparisons confirmed a significant increase in HCV RNA for Ant-miR-30c and significant decrease in HCV RNA for miR-130a. (*) P≤0.05.…”

EA treatment restored <i>Stat</i>5NKO-induced obese phenotype, improved energy metabolism and cold tolerance in the <i>Stat</i>5NKO obese mice. by Shu-Ping Fu (549948)

“…(E &F) EA treatment decreased <i>Stat</i>5NKO obese mice adipocyte size. …”

SIRT5 proviral activity is partially independent from the interaction with Nsp14. by Marius Walter (13775591)

“…B. Decrease in supernatant-associated viral mRNA levels in HCT-8 cells infected with HCoV-OC43 for 5 days at MOI = 0.1, and treated with SIRT5 inhibitor Sirt5-i, as shown by RT-qPCR. …”

Angiogenesis and mouse LLC tumor growth are suppressed by 6a-P peptide <i>in vivo</i>. by Tong-Young Lee (250877)

“…The mice were treated with the peptide or PBS twice a day after tumor cells injection. In mouse LLC animal model, the tumor sizes are decreased about 30% after the treatments (n = 5) (A). …”

Image_5_Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway.tif by Yating Wen (4017578)

“…Inhibition of ZFAS1 decreased the apoptotic rate of pORF5 and reduced the infectivity of C. trachomatis, and MAPK/p38 pathway was involved in anti-apoptotic effect induced by ZFAS1. …”

Compromised skeletal development in Trsp^fl/fl Col2a1-Cre mice. by Charlene M. Downey (149525)

“…(C) Micro-CT scans of the dorsal aspect of control (left) and experimental (right) skulls show smaller overall head size, rounding of the cranium (with possible decreased frontal bone ossification), and nasal bone shortening in the <i>Trsp^fl/fl Col2a1-Cre</i> mouse. …”

In native cartilage, lubricin bound to the surface facilitates HA aggregation near the surface (A). Lubricin likely entraps HA through entanglements, causing a local increase in viscosity near the tissue surface (A, inset). When lubricin is removed from the surface, HA does not aggregate (B) and surface viscosity is likely similar to the bulk (B, inset). Boundary lubrication by lubricin shifts the boundary regime down and increased viscosity near the surface shifts the elastoviscous transition such that the low friction regime occurs at lower sliding speeds consistent with viscous boundary lubrication (C). These phenomena of lubricin and HA replicate the lubrication by synovial fluid which transition to low friction at low speeds. By treating synovial fluid with hyaluronidase, friction is shifted back towards the boundary mode plateau as the fluid viscosity decreases, and trypsin treatment disrupts the synergy between lubricin and HA by digesting lubricin (n = 4; data points represent by Edward D. Bonnevie (830252)

“…By treating synovial fluid with hyaluronidase, friction is shifted back towards the boundary mode plateau as the fluid viscosity decreases, and trypsin treatment disrupts the synergy between lubricin and HA by digesting lubricin (n = 4; data points represent mean±SEM).…”

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain by Mohammad H., Merii

“…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …”
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The effects of let-7a on the embryo attachment, percentage outgrowth and outgrowth area <i>in vitro</i>. by Wei-Min Liu (1527772)

“…(c) let-7a decreased the trophoblast outgrowth area after 72-hour of culture. …”

A catalogue of dynamic, non-linear genetic effects in gene response following rapamycin treatment in yeast. by Avital Brodt (669454)

“…<p>(<b>A</b>) Genetic effect profiles (left) and gene expression profiles (right) at six time points following rapamycin treatment (columns) for all genes identified by DyVER. …”

Expression of mRFP does not perturb the severity of <i>opa1</i> RNAi and <i>marf</i> RNAi phenotypes. by Dnyanesh Dubal (12085942)

Influence of the order of addition of fusing partners on HCVpp 1a fusion inhibition by Arb. by Elodie Teissier (232354)

“…a<p>Arb (11.3 µM) was pre-incubated sequentially with either HCVpp or R₁₈-labeled liposomes or both for the indicated times at 37°C before initiating lipid mixing by decreasing pH to 5.0 as described in the legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015874#pone-0015874-g002" target="_blank">Figure 2</a>. …”

Downregulation of Opa1 and Marf does affect type II NB numbers but affect differentiated cells in lineage. by Dnyanesh Dubal (12085942)

SARS-CoV-2 Nsp14 interacts with human SIRT1. by Marius Walter (13775591)

“…Both drugs were cytotoxic at high concentrations and the apparent decrease in SIRT1 binding correlated with a similar decrease in the input lanes. …”

DataSheet1_Inhibiting DNA methylation as a strategy to enhance adipose-derived stem cells differentiation: Focus on the role of Akt/mTOR and Wnt/β-catenin pathways on adipogenesis.... by S. Ceccarelli (4569751)

“…Through functional assays, we observed a detrimental effect of 5-aza on ASC self-renewal capacity and migration, accompanied by actin cytoskeleton reorganization, with decreased stress fibers. …”

Analysis of proliferation in NBs depleted of Opa1 and Marf. by Dnyanesh Dubal (12085942)