Image_1_The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury.jpg by Petra Sucha (14234291)

“…Our results showed that deletion of AQP4 or TRPV4 channels alone leads to a significant worsening of ischemic brain injury at both time points, whereas their simultaneous deletion results in a smaller brain lesion at D1 but equal tissue damage at D7 when compared with controls. …”

Boxplots and pathway visualization of representative primary metabolites. by Ahmed Ramadan (508121)

“…<p>(<b>a</b>) and (b): Boxplot-visualizations for a subset of amino acids (A) and sugars and sugar alcohols(B) as determined for the three independent samples for the different time points and treatments as indicated on the x-axis. …”

Urine effects on grass and legume nitrogen isotopic composition: Pronounced short-term dynamics of δ¹⁵N by Bettina Tonn (5678663)

“…We applied cattle urine to a mixture of <i>Lolium perenne</i> and <i>Trifolium repens</i> in a pot experiment. …”

Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium Ferulate by Lichen Gao (423659)

“…<i>NR1I2</i> TGT haplotype (-25385T+g.7635G+g.8055T) carriers exhibited a significantly decreased AUC ratio, compared with TGT noncarriers, in the basal states (7.6±1.0 versus 9.7±1.0), while this result wasn't observed in <i>CYP2B6*6</i> noncarriers. …”

Nationwide Trends in Bacterial Meningitis before the Introduction of 13-Valent Pneumococcal Conjugate Vaccine—Burkina Faso, 2011–2013 by Dinanibè Kambiré (2173702)

“…Serotypes 1 (45%) and 12F/12A/12B/44/46 (8%) were most common. Among children aged <1 year, serotypes 5 (15%), 6A/6B (13%) and 1 (12%) predominated.…”

NIK is responsible for noncanonical NF-κB activation in ovarian cancer cell lines. by Masaya Uno (522188)

“…<p>(A) RMG-I and JHOC-5 cells were infected with lentivirus vectors expressing shRNA targeting <i>NIK</i> (shNIK-1) or <i>GFP</i> (shCtl). …”

Ten years of antiretroviral therapy: Incidences, patterns and risk factors of opportunistic infections in an urban Ugandan cohort by Dana Weissberg (5921303)

“…In patients developing OIs at a current CD4 cell count >200 cells/μL, factors independently associated with OI development were time-varying increase in viral load and time-varying decrease in hemoglobin, whereas a baseline CD4 cell count <50 cells/μL was protective.…”

The binding of HP1γ and cohesin to D4Z4 is lost in FSHD patients. by Weihua Zeng (262054)

“…<p>(A) HP1γ, but not HP1α, binds to D4Z4 in HeLa cells. 4qHox endpoint PCR of ChIP DNA using antibodies against HP1γ and HP1α is shown. …”

Supporting data for "oral health care in older adults" by Kit Ying Chan (10285988)

“…Meta-analysis found a decrease in the number of new root caries by 0.55 (95% CI: 0.32-0.78; p<0.001) and an overall proportion of arrested root caries of 42% (95% CI: 33% to 49%; p<0.001) after 38% SDF application at the 24-month follow-up.…”

Basic Quantum Magnetic Interaction Data by Bhekuzulu Khumalo (10789827)

“…And 2, 0.5mm out. <br></div><div><br></div><div>All three experiment thus involved 960 seperate measurements, a most detail understanding of the magnet.…”

Enhancement of neurodegeneration, actin rod formation, Drp1 mislocalization, and mitochondrial elongation in mice expressing human tau and human LRRK2. by Farah H. Bardai (6107924)

“…Controls are age-matched nontransgenic mice. Mice are 5.5 months old. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2006265#pbio.2006265.s008" target="_blank">S1 Data</a> for individual numerical values underlying the summary data displayed in C, D, G, H, and I. …”

Filamentous bacteria. by Andrea Mückl (847776)

“…<p>(<b>A)</b> Histogram of the cell length (calculated from 1000 cells each) at different time points at 100% induction level (corresponding to 500 μM IPTG and 107 nM aTc). …”

Cort expression leads to proteasome-mediated degradation of Mtrm in cell culture. by Zachary J. Whitfield (453399)

“…Only wild-type Cort leads to decreased levels of tagged Mtrm protein. The <i>RH65</i> mutation results in a premature stop codon in Cort. …”

Difference between cystatin C- and creatinine-based estimated glomerular filtration rate and incident hypertension and the mediating role of Triglyceride Glucose Index by Zixuan Zhang (6957035)

“…During a mean follow-up period of 5.0 years, 613 new cases of hypertension occurred. …”

Image_2_Sustainable valorization of co-products from asparagus cultivation by obtaining bioactive compounds.jpeg by Isabel Viera Alcaide (16538130)

“…Leaving these residues on the fields after harvesting negatively affects the following asparagus crops, since they release autotoxic (allelopathic) substances into the soil, whose accumulation causes that asparagus yields gradually decrease over the years, becoming an unprofitable crop in a period of about 10 to 15 years. …”

Image 1_Muscle fascicle length adaptations to high-velocity training in young adults with cerebral palsy.jpeg by Tessa L. Gallinger (21346835)

“…While HVT did not result in significant changes in maximal shortening velocity (V_max) or maximal peak power output (P_max), a large effect size for v_max following training in CP-T was seen (+45.2 ± 76.4%, d = 0.909, p = 0.452), in contrast to CP-NT (+2.9 ± 70.5%, d = 0.059, p = 1.00). …”

<i>In vitro</i> and <i>in vivo</i> genotoxic effects of straight versus tangled multi-walled carbon nanotubes by Julia Catalán (837558)

“…No systemic genotoxic effects, assessed by the γ-H2AX assay in blood mononuclear leukocytes or by micronucleated polychromatic erythrocytes (MNPCEs) in bone marrow or blood, were observed for MWCNT-S by either exposure technique. MWCNT-T showed a dose-related <i>decrease</i> in DNA damage in BAL and lung cells of mice after a single pharyngeal aspiration (1–200 μg/mouse) and in MNPCEs after inhalation exposure (17.5 mg/m³). …”

Repression of miR-29 during outlet obstruction is associated with increased levels of miR-29 target messenger RNAs (mRNAs). by Mari Ekman (168258)

“…<p>Gene expression was assessed (<i>n</i>=6−8) at 10 days and at 6 weeks following outlet obstruction using microarrays and compared with sham-operated controls and with rats where the obstruction had been removed for 10 days. (A) Relative increase (left vs. sham) and decrease (right vs. 6 weeks) of the top 50 mRNA targets of miR-29 when miR-29 was repressed at 10 days and when miR-29 recovered after de-obstruction (c.f. …”

MmuPV1 integration, host gene expression, and cell growth. by Lulu Yu (737362)

“…<b>B and C,</b> Expression of MmuPV1 E6E7 (green) correlates with a decrease in the expression of mouse Krt10 and Fabp5 (red) in the tail tumor tissues of FoxN1^nu/nu at day 21 as measured by RNA ISH using dual immunofluorescence RNAscope analysis. …”

Gli2 and Full-Length Gli3 Function Is Disrupted in <i>Tg737</i>^{Δ2–3β-gal} Mutant Cells by Courtney J Haycraft (60266)

“…<div><p>(A) Infection of primary limb bud cells (E11.5) with Gli1::GFP expressing adenovirus induces increased <i>Ptch1</i> transcription in wild-type cells when compared to infection with GFP-only virus (GFP). …”