Dynamics of Intraocular IFN-γ, IL-17 and IL-10-Producing Cell Populations during Relapsing and Monophasic Rat Experimental Autoimmune Uveitis by Ulrike Kaufmann (120794)

“…During relapsing uveitis an increase of intraocular IFN-γ+ cells and a concomitant decrease of IL-17+ cells was detected, while IL-10+ populations remained stable. …”

Structural homology models of hGPR83 in putative complexes with arrestin and G-protein. by Anne Müller (103420)

“…<p><b>A)</b> The presented structural hGPR83-arrestin complex homology model (backbone cartoon) is mainly based on the crystal structure of rhodopsin with bound arrestin (PDB entry 5DGY, [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168260#pone.0168260.ref043" target="_blank">43</a>]), which served as a template for modeling procedures. …”

Table_1_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease by Viktor Martyanov (396510)

“…Clinical response was defined as decrease of >5 or >20% from baseline in the modified Rodnan Skin Score (MRSS). …”

Community health workers for non-communicable diseases prevention and control in developing countries: Evidence and implications by Gursimer Jeet (535149)

“…The duration of the studies ranged from mean follow up of 4 months for some risk factors to 19 months, and primary responsibilities of health workers included health promotion, treatment adherence and follow ups. Only a single trial reported all-cause mortality. The pooled effect computed indicated an increase in tobacco cessation (RR: 2.0, 95%CI: 1.11, 3.58, moderate-quality evidence) and a decrease in systolic blood pressure ((MD: -4.80, 95% CI: -8.12, -1.49, I² = 93%, very low-quality evidence), diastolic blood pressure ((MD: -2.88, 95% CI: -5.65, -0.10, I² = 96%, very low-quality evidence)) and blood sugar levels (glycated haemoglobin MD: -0.83%, 95%CI: -1.25,-0.41). …”

Table_1_Embryonic Thermal Manipulation Affects Ventilation, Metabolism, Thermal Control and Central Dopamine in Newly Hatched and Juvenile Chicks.DOCX by Aline C. G. Rocha (10984392)

“…Regarding 14d animals, the HT females showed a decrease in V._E and V.O₂ compared to CT and LT groups, while the HT males displayed a lower V.O₂ compared to CT males, but no changes in V.…”

The bioinfomatics analysis of the M1 macrophage-related gene CXCL9 signature in cervical cancer by Wenxin Liao (18974243)

“…</p> <p>There were 77 positive coexpression genes and 5 negative coexpression genes in M1 macrophage. …”

Table_4_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Table_3_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Table_2_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Image_1_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.pdf by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Percent weight loss from day 0 weight during infection studies. by F. Christopher Peritore-Galve (12102393)

Global structural model fit statistics and path coefficients. by Ashkan Hassani (16406616)

“…Unit change represents the b-coefficient value multiplied by the standard deviation of the outcome variable (i.e., people per room standard deviation = 0.98 multiplied by a standardized coefficient of 0.18 results in a 0.18-point increase [0.98 x 0.18] in reported poor emotional health).…”

IRRIGATION DEFICIT STRATEGIES ON PHYSIOLOGICAL AND PRODUCTIVE PARAMETERS OF 'TOMMY ATKINS' MANGO by MARCELO ROCHA DOS SANTOS (6151754)

“…The partial root-zone drying irrigation with 60 and 40% of ETc causes a decrease in the 'Tommy Atkins' mango yield. The regulated deficit irrigation up to 50% of ETc, applied at the fruit maturation stage, maintain the yield and water use efficiency.…”

Water restriction, salinity and depth influence the germination and emergence of sourgrass by Jackson Zambão (10460748)

Table_1_Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics.docx by Monica L. Fernández-Quintero (6178163)

“…We observed a substantial rigidification upon affinity maturation, which is accompanied by a higher number of contacts, thereby contributing to the decrease in flexibility. …”

DataSheet_1_Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals.docx by Lingling Ding (361046)

“…</p>Conclusions<p>Despite similar plasma CTSD levels, type 2 diabetic male individuals showed increased plasma CTSD activity compared to healthy males, which was independently linked to plasma FFA levels. Our data therefore point toward plasma CTSD as a metabolic regulator in male type 2 diabetes.…”

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx by Shengli Wang (4318522)

“…</p><p>Methods: This study established experimental and control groups, employing a five-point sampling method to collect samples of the rhizosphere soil and tobacco leaves at four different growth stages. …”

Supplementary Material for: Pulmonary Gas Exchange Improves over the First Year in Preterm Infants with and without Bronchopulmonary Dysplasia by Choi Y.J. (10148741)

“…Results were examined cross-sectionally at each time point, and longitudinally using generalized linear regression. …”

Latency varies across water conditions. by Mallory E. Udell (11302100)

“…As water temperature is decreased, latency is lengthened. Linear regression indicated that temperature explains 63% of the variance in latency when tested between 47–50°C with the water mixing at a constant, low speed. …”