The Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs) by Guy Martel (391836)

“…Inhibition of TPL2 activity with a pharmacological inhibitor (Compound 1) not only prevented ERK1/ERK2 activation but also decreased cytokine synthesis in response to pathogen-associated molecular patterns. …”

Electrochemical Properties of Quinone-Based Organic Electrodes in LiCl/DMSO Electrolyte Solutions for Fluorine-Free Lithium Secondary Batteries (Supporting Information) by Sho OKUBO (20819672)

“…<div>An organic electrolyte solution of 1.0 mol dm⁻³ LiCl/dimethyl sulfoxide (DMSO) was investigated for a fluorine-free battery with an electrode using <i>2,5</i>-dimethoxy-<i>1,4</i>-benzoquinone (DMBQ) as the n-type active material and styrene butadiene rubber (SBR) as the binder. …”

Geometrical parameters effect on aerodynamic performance of infinite tubercle leading edge wings by Amirfarhang Nikkhoo (19754843)

“…Results reveal that increasing the thickness of the infinite wing by approximately 9.5% results in a decrease of lift and drag coefficients by 19.8% and 12%, respectively. …”

Pressure and resistance of the lips in subjects with and without occlusal change by Clarissa Evelyn Bandeira Paulino (7291685)

“…The significance level was considered 5%. Results: a decrease in pressure and resistance values wasobserved in all patients, including Angle’s class I group. …”

Fig 8 - by Li Jiashen (20552690)

“…<p>Fixing λ_<i>G</i> = 0.25 and adjusting the size of λ_<i>L</i>, the time resolution of the high-frequency part of the spectrogram gradually decreases with the gradual decrease of λ_<i>L</i>, and the frequency resolution gradually increases, (a-d) Figs. are the spectrograms extracted by different sizes of λ_<i>L</i>, and the corresponding parameter settings are: (a)(λ_<i>G</i> = 0.25, λ_<i>L</i> = 1), (b)(λ_<i>G</i> = 0.25, λ_<i>L</i> = 0.5), (c)(λ_<i>G</i> = 0.25, λ_<i>L</i> = 0.1), (d)(λ_<i>G</i> = 0.25, λ_<i>L</i> = 0.01).…”

Reduced mating efficiency for supersensitive cells. by Weitao Chen (3155154)

“…The distance between polarisomes was plotted as a function of time. The distances did not steadily decrease as was observed in the normal sensitivity simulations. …”

AZ2.0 by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, <br>respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of <br>valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the <br>percentage repeat, resulted due to removal of mis-assembly and closure of gaps fromover the earlier <br>assembly (v1.0). …”

Fast Temperature-Gradient COLD PCR for rs7480526. by Stefania Byrou (5558807)

“…<p>The input conventional PCR products resulted from spiked genomic DNA amplification consisting of 95% maternal alleles (blue) and 5% fetal alleles (red). First, the PCR products are subjected to a number of cycles of regular PCR to produce an initial pool of target amplicons. …”

The effect of the G369E mutation on the structure of BCKDK protein is shown. by J. Samuel Zigler Jr. (3145044)

“…In the mutant, the helix containing residue E369 is moving outward from the ADP binding site due to repulsion from the negatively charged residue E275. This might suggest a decrease in ADP binding activity by the mutant enzyme due to the replacement of glycine in normal BCKDK by the negatively charged glutamic acid in the mutant variant.…”

Reversal of hyperglycemia in NOD mice after cell therapy. by Reza B. Jalili (845889)

“…Fib.) or IDO expressing fibroblasts and an IDO inhibitor, 1-methyl tryptophan (IDO Fib. + 1MT) remained hyperglycemic (<i>n</i> = 5 mice/ group). Kaplan-Meier survival curve with log-rank analysis (<b>C</b>) showed significant decrease in diabetes rate of IDO fibroblast treated group. …”

Biosorption Potential of the Aspergillus sp. and Insights into Secondary Metabolism in the Presence of Copper and Lead by Maurício Augusto P. M. S. Alves (8527671)

“…<div><p>The fungus Aspergillus sp. was isolated from copper mining rejects and cultured in a liquid culture medium (potato dextrose, PD) enriched with CuSO4.5H2O and Pb(NO3)2 in different concentrations. …”

DataSheet_1_Including Volume Effects in Biological Treatment Plan Optimization for Carbon Ion Therapy: Generalized Equivalent Uniform Dose-Based Objective in TRiP98.pdf by Marco Battestini (12268814)

“…In particular, for a plan containing multiple OARs, we obtained the same target coverage and similar DVHs for OARs with a small volume effect while decreasing the mean dose received by the proximal parotid, thus reducing its NTCP by a factor of 2.5. …”

SMAD2/3 and TGF-ß1 suppress expression from the megalin promoter. by Felipe Cabezas (231082)

“…(B) The overexpression of SMAD factors increased luciferase expression from the p800luc plasmid (positive control). Data in (A) and (B) are expressed as the means ± SD, and significant differences with the control (pCMV5) are indicated by *P≤ 0.001. …”

Immediate Changes in Peripapillary Retinal Vasculature after Intraocular Pressure Elevation -an Optical Coherence Tomography Angiography Study by Xiaolei Wang (139592)

“…</p> <p><b>Conclusions</b>: LPI-induced IOP spikes resulted in a decrease in retina vessel density with PACS eyes by OCTA. …”

Table_3_Ultramicronized N-Palmitoylethanolamine Supplementation for Long-Lasting, Low-Dosed Morphine Antinociception.DOC by Lorenzo Di Cesare Mannelli (600627)

“…The same pain threshold increase was achieved in animals using preemptive PEA (30 mg/kg, daily) joined to a combinatorial acute treatment with morphine (5–20 mg/kg s.c.) and PEA (30–120 mg/kg, p.o.). …”

Data Sheet 1_Activation of the Nrf2/HO-1 pathway restores N-acetylcysteine-induced impairment of the hypothalamus-pituitary-adrenal axis negative feedback by up-regulating GRα expr... by Amanda Silva Chaves (20466374)

“…Furthermore, NAC induced adrenal enlargement and hypercorticoidism, along with a decrease in the GRα expression and an increase of GRβ expression in the pituitary gland. …”

Supplementary Material for: Peridialytic Erythropoietin versus Roxadustat in Hemodialysis-dependent CKD Patients by figshare admin karger (2628495)

“…A propensity score-matched analysis (1:1 ratio; caliper width: 0.02) was conducted to minimize the impact of confounding factors. …”

Image1_The involvement of the noradrenergic system in the antinociceptive effect of cucurbitacin D on mice with paclitaxel-induced neuropathic pain.jpeg by Keun-Tae Park (14326092)

“…The cucurbitacin D dose-dependently (0.025, 0.1, and 0.5 mg/kg) attenuated both allodynia types. In the spinal cord, paclitaxel injection increased the gene expression of noradrenergic (α₁-and α₂-adrenergic) receptors but not serotonergic (5-HT_1A and ₃) receptors. …”

Image1_Morphological, electrophysiological, and molecular alterations in foetal noncompacted cardiomyopathy induced by disruption of ROCK signalling.TIF by David Sedmera (636625)

“…The cause of the early noncompaction at E15.5 was attributed to a decrease in proliferation in the developing ventricular wall. …”

Influence of the main stem pruning and fruit thinning on quality of melon by Rafaella Martins de Araújo Ferreira (12689661)

“…In Amaregal melon, fruits showed longer length (134 mm) and greater flesh firmness (40 N) when thinning was carried out on 6 DARB, and as thinning was delayed, it found a decrease in the values of soluble solids, SS: TA ratio and pH. …”