Image_6_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…The receiver operating characteristic curve analysis showed that the optimal cut-off values of early diastolic SR <0.8 s⁻¹ and indexed RA area > 8.8 cm²/BSA had the best accuracy in identifying patients with RV diastolic dysfunction, with 87% sensitivity and 82% specificity. During a mean follow-up of 25.2 months after pulmonary endarterectomy, the preoperative indexed RA area was shown as an independent risk factor of the decreased 6MWT distance.…”

Image_3_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…The receiver operating characteristic curve analysis showed that the optimal cut-off values of early diastolic SR <0.8 s⁻¹ and indexed RA area > 8.8 cm²/BSA had the best accuracy in identifying patients with RV diastolic dysfunction, with 87% sensitivity and 82% specificity. During a mean follow-up of 25.2 months after pulmonary endarterectomy, the preoperative indexed RA area was shown as an independent risk factor of the decreased 6MWT distance.…”

Image_6_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Table_1_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.doc by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_4_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

PBMC reduces cold hypersensitivity in CFA and CCI but not oxaliplatin pain models. by Wendy M. Knowlton (342969)

“…<b>B</b>) PBMC (10 mg/kg) administered to wildtype mice on day two post-CFA-injection resulted in a significant decrease in scores to 2.5±0.2 (Student's t-test, **p<0.01). …”

Image_3_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Table_2_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.doc by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_2_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

Image_1_Function of the fliK Gene in Pseudomonas plecoglossicida Pathogenicity and Epinephelus coioides’ Immune Response.pdf by Zixu Liu (9204374)

“…The shRNA-406 mutant with the maximum silencing efficiency (97.5%) was chosen for further study. Compared with the wild-type (WT) P. plecoglossicida strain, silencing fliK in the fliK-RNA interference (RNAi) strain resulted in a significant decrease in growth, motility, chemotaxis, adhesion, and biofilm formation in P. plecoglossicida. …”

TF function predicted from regulatory parameters <i>α</i> and <i>β</i>. by Md Zulfikar Ali (11965544)

“…Black contours mark FC_max = 1 and subsequent contours represent 100–fold increase or decrease in FC_max. The observed regulation from a TF depends on promoter strength. …”

High levels of glucose alter the expressions of PRC2 component and related genes. by Michael Anthony Ruiz (726055)

“…<b>B:</b> After 24 exposure to D-glucose, KDM6A and KDM6B levels did not change in HG. After 48 hours, KDM6A was significantly decreased compared to NG and OSM controls, while KDM6B showed no change. [* p < 0.05 compared to NG; n = 6; data expressed as mean ± SEM, normalized to β-actin and expressed as a fold change of NG].…”

DataSheet2_Polymorphisms of nucleotide excision repair genes associated with colorectal cancer risk: Meta-analysis and trial sequential analysis.docx by Chuncheng Yi (10324538)

“…It also showed that ERCC5 rs17655 increased CRC risk in the allele (OR = 1.104, 95% CI = 1.039–1.173, p = 0.001), homozygous (OR = 1.164, 95% CI = 1.018–1.329, p = 0.026), heterozygous (OR = 1.271, 95% CI = 1.018–1.329, p < 0.001), dominant (OR = 1.241, 95% CI = 1.135–1.358, p < 0.001) and over-dominant (OR = 0.828, 95% CI = 0.762–0.900, p < 0.001) models, especially among Asians.…”

DataSheet3_Polymorphisms of nucleotide excision repair genes associated with colorectal cancer risk: Meta-analysis and trial sequential analysis.docx by Chuncheng Yi (10324538)

“…It also showed that ERCC5 rs17655 increased CRC risk in the allele (OR = 1.104, 95% CI = 1.039–1.173, p = 0.001), homozygous (OR = 1.164, 95% CI = 1.018–1.329, p = 0.026), heterozygous (OR = 1.271, 95% CI = 1.018–1.329, p < 0.001), dominant (OR = 1.241, 95% CI = 1.135–1.358, p < 0.001) and over-dominant (OR = 0.828, 95% CI = 0.762–0.900, p < 0.001) models, especially among Asians.…”

DataSheet1_Polymorphisms of nucleotide excision repair genes associated with colorectal cancer risk: Meta-analysis and trial sequential analysis.docx by Chuncheng Yi (10324538)

“…It also showed that ERCC5 rs17655 increased CRC risk in the allele (OR = 1.104, 95% CI = 1.039–1.173, p = 0.001), homozygous (OR = 1.164, 95% CI = 1.018–1.329, p = 0.026), heterozygous (OR = 1.271, 95% CI = 1.018–1.329, p < 0.001), dominant (OR = 1.241, 95% CI = 1.135–1.358, p < 0.001) and over-dominant (OR = 0.828, 95% CI = 0.762–0.900, p < 0.001) models, especially among Asians.…”

HCMV-Induced Changes in Glycolytic Metabolites by Joshua Munger (66985)

“…Transcriptional data are depicted graphically at the relevant enzymatic step by the following symbols (shown in red): +, increased and −, decreased ≥1.5-fold in HCMV infection versus mock infection and <i>p</i> < 0.05 based on ANOVA analysis; NC, no change, either not significant by ANOVA or effect of HCMV < 1.5-fold. …”

Figure 4 from Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients by Lauren Polyakov (21672045)

“…<p>Continued use of corticosteroids during anti–PD-L1 therapy correlates with decreased survival in a preclinical model. <b>A,</b> Experimental set-up. …”

Rat splenocytes control intramacrophage <i>Francisella</i> growth that is accompanied by IFN-γ and NO production. by Roberto De Pascalis (187305)

“…<p>BMMΦ from Fischer 344 rats were infected with LVS (Macs), and co-cultured with naïve splenocytes or with immune splenocytes derived from LVS-vaccinated rats. Decreasing numbers of splenocytes were added to a constant number of confluent LVS-infected macrophages, where 1 = 5 x 10⁶, 1/2 = 2.5 x 10⁶, 1/4 = 1.25 x 10⁶, 1/8 = 0.625 x 10⁶, 1/16 = 0.312 x 10⁶, 1/32 = 0.156 x 10⁶ splenocytes. …”

Knockdown of endogenous Miz1 attenuates Hh signaling. by Jiuyi Lu (409742)

“…Stable NIH 3T3 cells infected with either a scrambled shRNA (Scr) or Miz1 shRNA lentiviruses (#3 and #5) were transfected with the Hh-responsive reporter and treated with DMSO or SAG. …”

EFFECTS OF RENAL DYSFUNCTION ON HEALING OF COLONIC ANASTOMOSIS: EXPERIMENTAL STUDY IN WISTAR RATS by Carlos Eduardo da SILVA (6073667)

“…Decrease of granulation tissue formation (border reepithelialization p=0,0196, angiofibroblast proliferation p=0.0379), mean collagen I (p=0,0009) and collagen III (p=0,016), microvascular density (p=0,0074), cell proliferation nuclear antigen (p<0,0000) and myofibroblasts (p<0,0001). …”