Image_2_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Image_1_Is Proton Therapy a “Pro” for Breast Cancer? A Comparison of Proton vs. Non-proton Radiotherapy Using the National Cancer Database.pdf by Mudit Chowdhary (6016496)

“…On multivariate logistic analysis, the following factors were found to be significant for receipt of PRT (all p < 0.05): academic facility (odds ratio [OR] = 2.50), South (OR = 2.01) and West location (OR = 12.43), left-sided (OR = 1.21), ER-positive (OR = 1.59), and mastectomy (OR = 1.47); pT2-T4 disease predicted for decrease use (OR = 0.79). …”

Evidence of saturation of protein fold space as a function of time. by Lukasz Jaroszewski (4284)

“…All cases in which FATCAT algorithm found at least 50 equivalent residues superimposed with C_α RMSD <3 Å were regarded as putative cases of “significant partial similarity” and were subject to visual verification. …”

Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools by Marleen Werkman (543388)

Changes in Aβ products caused by gradual saturation of γ-secretase. by Željko M. Svedružić (105215)

“…<p>Saturation of γ-secretase with its C99 substrate leads to decrease in Aβ40 production with concomitant increase in production of the longer more hydrophobic Aβ peptides and Aβ42/Aβ40 ratio. …”

Ca²⁺ transient activities of hippocampal astrocytes in the neuroinflammation model. by Jae-Hong Kim (124622)

A Novel Nonsense Mutation in the <em>DMP1</em> Gene Identified by a Genome-Wide Association Study Is Responsible for Inherited Rickets in Corriedale Sheep by Xia Zhao (215170)

“…Among 35 candidate genes in this region, the dentin matrix protein 1 gene (<em>DMP1</em>) was sequenced to reveal a nonsense mutation 250C/T on exon 6. This mutation introduced a stop codon (R145X) and could truncate C-terminal amino acids. …”

Data_Sheet_1_The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongat... by Sofia Esquivel-Elizondo (4438618)

“…However, this was considerably higher at 83.1 ± 0.44% when both fructose and n-butyrate (electron acceptor) were combined as a substrate. A comparison of 7D4C2 cultures with fructose and n-butyrate with an increasing pH value from 4.5 to 9.0 showed a decreasing n-caproate specificity from ∼92% at mildly acidic pH (pH 4.5-5.0) to ∼24% at alkaline pH (pH 9.0). …”

Effects of chronic ISO infusion on cardiac function in Epac1TG. by Yoshiki Ohnuki (576298)

A COX inhibitor does not prevent the development of tactile allodynia after nerve injury. by Shigeo Hasegawa (249454)

“…Scale bar, 50 µm. B. The COX-1 inhibitor SC-560 (20 nmol/10 µl) administered through a catheter whose tip was positioned near the L5 DRG once daily for 14 days did not suppress the development of nerve injury-induced a decrease in the paw withdrawal threshold of tactile stimulation using von Frey filaments. …”

Optogenetic stimulation of the hippocampal CA1 astrocytes reduced the hippocampal long-term synaptic plasticity and expression of the NMDA receptors. by Jae-Hong Kim (124622)

Differential splicing of a 12-nt microexon in TEAD2. by Sarah A. Head (6066398)

NeoA prevents tumor cell elongation and invasion into Matrigel. by Pamela Austin (248283)

“…Scale bar, 50 µm. (C) NeoA treatment results in loss of polarity and decreased actin ruffling. f-actin staining of cells treated with either DMSO or 3.2 µM NeoA for 90 min. …”

D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway - Fig 9 by Ana Belén Gómez-SanMiguel (3170115)

“…<p>Effect of D-Trp(8)-γMSH (0, 50 or 200 nM) on; phospho-NF-κB(p65)Ser276 (A), NF-κB(p65) (B), phospho-Akt (C) Akt (D), IGF-I mRNA (E) and MHC I mRNA (F) in L6 myotubes cell cultures incubated with TNFα (10 μg/ml) or DMEM. …”

Identification of OB gamma as a reliable marker of sleep/wake states. by Sophie Bagur (5808542)

“…Filtered signals from the OB in the gamma band (OB-γ, 50–70 Hz) illustrate the remarkable decrease in gamma power during sleep states. …”

Data_Sheet_1_Disturbance-Mediated Changes in Coral Reef Habitat Provoke a Positive Feeding Response in a Major Coral Reef Detritivore, Ctenochaetus striatus.docx by Xianzhi Lin (232749)

“…The biomass of C. striatus showed an inverted U-shaped relationship with coral coverage and a significant positive correlation with SAT coverage (p < 0.05), indicating that rising SAT coverage associated with moderate coral loss provoked a feeding response in C. striatus. …”

A deletion bias creates the appearance of conserved site spacing. by Richard W. Lusk (106685)

“…However, the deletion bias, on average, ratchets sites together over time, correlating any two pairs of sites' evolution. (C–E) After starting 30 (C), 50 (D), or 100 (E) base pairs apart at a speciation event, orthologous pairs of sites are subjected to a simple test of spacing conservation. …”

Patient characteristics at baseline. by Jiska B. Snoeck-Stroband (835520)

“…<p>^║PC₂₀ methacholine is expressed as geometric mean (standard deviation in doubling dose (DD)).</p><p>^‡range 1 to 5 (higher scores indicate more dyspnea);</p><p>^†range 0 (best) to 100 (worst score);</p><p>^§range 0 (best) to 6 (worst score).…”

Agent movement, interaction rules, and resulting trajectories in a box. by Jorin Diemer (11140736)

“…<b>G</b> Cross-sectional distribution of agents (<i>N</i> = 1000), simulated in a channel with a width and height of 50 μm. Agent density increases towards boundaries and corners. …”

Expected productivity <i>g</i>_<i>i</i> of a research unit as a function of its budget <i>x</i>. by Miguel Navascués (164739)