Identification of Novel Single Nucleotide Polymorphisms in Inflammatory Genes as Risk Factors Associated with Trachomatous Trichiasis by Berna Atik (270071)

“…TT risk decreased 5 times [odds ratio = 0.2 (95% confidence interval 0.11.–0.33), <em>p</em> = 0.001] with the combination of TNFA (-308A), LTA (252A), VCAM1 (-1594C), SCYA 11 (23T) minor allele, and the combination of TNFA (-308A), IL9 (113M), IL1B (5′UTR-T), and VCAM1 (-1594C). …”

Fig 6 - by Thomas S. Kraft (3255267)

“…All scenarios are depicted relative to baseline (black), with red-blue colors depicting degree of increase–decrease in target parameter. The data underlying this Figure can be found in <a href="http://10.0.68.197/OSF.IO/7YB2M" target="_blank">http://doi.org/10.17605/OSF.IO/7YB2M</a> (files: <a href="https://osf.io/9qgpr" target="_blank">https://osf.io/9qgpr</a>, <a href="https://osf.io/57bm8" target="_blank">https://osf.io/57bm8</a>, <a href="https://osf.io/gp8sn" target="_blank">https://osf.io/gp8sn</a>, <a href="https://osf.io/tewp4" target="_blank">https://osf.io/tewp4</a>, <a href="https://osf.io/p8aqr" target="_blank">https://osf.io/p8aqr</a>, <a href="https://osf.io/4xdhc" target="_blank">https://osf.io/4xdhc</a>, <a href="https://osf.io/vp562" target="_blank">https://osf.io/vp562</a>, <a href="https://osf.io/42kxf" target="_blank">https://osf.io/42kxf</a>, <a href="https://osf.io/anfhz" target="_blank">https://osf.io/anfhz</a>, <a href="https://osf.io/hav6t" target="_blank">https://osf.io/hav6t</a>, <a href="https://osf.io/xjubn" target="_blank">https://osf.io/xjubn</a>, <a href="https://osf.io/h5fxe" target="_blank">https://osf.io/h5fxe</a>, <a href="https://osf.io/f798u" target="_blank">https://osf.io/f798u</a>, <a href="https://osf.io/a5cvm" target="_blank">https://osf.io/a5cvm</a>, <a href="https://osf.io/ykt52" target="_blank">https://osf.io/ykt52</a>, <a href="https://osf.io/cer5h" target="_blank">https://osf.io/cer5h</a>).…”

Assembly-induced changes in the rotation curve. by Rifka Vlijm (133750)

“…<b>C </b><i>NAP1, H3/H4 addition:</i> The rotation curves before (red squares) and after (blue circles) 5.6 nM NAP1 preincubated with 1.6 nM H3 and 1.6 nM H4 is flushed in (experiment as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046306#pone-0046306-g002" target="_blank">Figure 2C</a>). …”

Synthesis, Structures, and Luminescent and Magnetic Properties of Ln−Ag Heterometal−Organic Frameworks by Xiao-Qing Zhao (2064592)

“…Compounds <b>2</b>−<b>5</b> display a 2D honeycomb-like structure with 18-membered Ln₃Ag₃O₁₂ motifs, and compounds <b>6</b>−<b>10</b> can be described as a sandwich-like 3D framework built of a 3D Ag⁺-homometallic net and 2D Ln³⁺−4⁴ layer. …”

The function of EB1 and Tau is altered during ageing. by Pilar Okenve-Ramos (18150546)

“…In aged specimens, axons show a decrease in EB1 and GFP-Tau (dashed cyan boxes in A and E are shown as 2- and 2.3-fold magnified insets, respectively. …”

Data_Sheet_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.docx by Hongxiang Lu (2947089)

“…Furthermore, the NRI increased 25.18% (95% CI = 17.84–32.51%) (P = 6.00 × 10^–5).</p>Conclusion<p>Our finding indicated that genetic variants could enhance the predictive power of the risk model for sepsis and highlighted the application among trauma patients, suggesting that the sepsis risk assessment model will be a promising screening and prediction tool for the high-risk population.…”

Opposing mechanisms by which miRNAs mediate distinct Nrf1 and Nrf2 regulation of epithelial–mesenchymal transition in hepatocellular carcinoma by Juan Chen (61123)

“…The <i>Nrf1α</i>^{<i>–/–</i>}-leading EMT results from a significant decrease in the epithelial CDH1 expression, plus another increased expression of the mesenchymal CDH2. …”

Supplementary information files for "The effect of 90 and 120 min of running on the determinants of endurance performance in well-trained male marathon runners" by Michele Zanini (8484084)

“…During the runs, respiratory gases were collected at 15 min intervals to quantify RE. Decreases in V̇O2peak (−3.1%, p = 0.04 [post-90]; −7.1%, p < 0.001 [post-120]) and subsequent increases in FULT (+2.8%, p = 0.03 [post-90]; +4.9% p = 0.01 [post-120]) both occurred at an increasing rate with run duration, with FULT changes linked to the decreased V̇O2peak, while RE (mL·kg−1·km−1) deteriorated more linearly with time (by 4.2% [post-90] and 5.8% [post-120], p < 0.001). sLT also showed a nonlinear decrease, from 14.0 to 13.5 (p = 0.01 post-90), to 13.0 km·h−1 (p < 0.001 post-120). …”

Data_Sheet_1_Effect of LED Spectrum on the Quality and Nitrogen Metabolism of Lettuce Under Recycled Hydroponics.docx by Jie Li (15030)

“…Correlation analysis showed that the relative expression levels between HY5 and NR/NiR presented a significantly negative correlation. …”

Gal-3 upregulation in hypoxia depends on HIF-1α and NF-κB and is blocked by cicloheximide. by Rafael Yamashita Ikemori (698128)

“…The exposure to HIF-1α inhibitor 10 µm (CAS 934593-90-5) demonstrated gal-3 decreased induction by qRT-PCR in cells exposed to hypoxia, but not normoxia and CoCl₂. …”

Data_Sheet_1_Response Mechanism of Endogenous Hormones of Potential Storage Root to Phosphorus and Its Relationship With Yield and Appearance Quality of Sweetpotato.ZIP by Cheng-cheng Si (12588394)

“…Moreover, a significant decrease in the expression of AAO and concentration of ABA was observed from 10 to 30 days after planting, and a significant increase was observed after 40 days of planting. …”

Data_Sheet_1_The development and nutritional quality of Lyophyllum decastes affected by monochromatic or mixed light provided by light-emitting diode.docx by Xiaoli Chen (102563)

“…The stipe length, stipe diameter, pileus diameter and the weight of fruiting bodies exposed to RB significantly increased by 8.0, 28.7, 18.3, and 58.2% respectively, compared to the control (p < 0.05). B significantly decreased the stipe length and the weight of fruiting body, with a decrease of 8.5 and 20.2% respectively, compared to the control (p < 0.05). …”

Optimal Route for Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation to Protect Against Neonatal Hyperoxic Lung Injury: Gene Expression Profiles and Histopath... by Dong Kyung Sung (287830)

“…The number of ED-1 positive cells was significantly decreased by both IT and IV transplantations. However, IT administration of MSCs resulted in a greater decrease in MAV and ED-1 positive cells compared to IV administration. …”

Image_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.TIF by Hongxiang Lu (2947089)

“…Furthermore, the NRI increased 25.18% (95% CI = 17.84–32.51%) (P = 6.00 × 10^–5).</p>Conclusion<p>Our finding indicated that genetic variants could enhance the predictive power of the risk model for sepsis and highlighted the application among trauma patients, suggesting that the sepsis risk assessment model will be a promising screening and prediction tool for the high-risk population.…”

Neonatal hyper- and hypothyroidism alter the myoglobin gene expression program in adulthood by K. de Picoli Souza (6936788)

“…Conversely, hypothyroidism at P5 markedly decreased (60%) ventricular myoglobin mRNA. …”

Image_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_4_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIFF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”