Table_3_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…Arterial stiffness did not significantly change among all AFB and B25. However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

Table_1_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.docx by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

DataSheet_1_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

DataSheet_3_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

DataSheet_2_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

Oxygen concentration in the respiration chamber. by Pernille Nielsen (4249918)

“…Linear regression lines, regression equations and R² are given on the figure. The theoretical decrease in oxygen concentration in the respiration chamber (broken lines) calculated for the highest oxygen consumption (0.8 mg O₂ h^-1 g^-1) from literature ([<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref049" target="_blank">49</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref050" target="_blank">50</a>] and for the lowest (0.13 mg O₂ h^-1 g^-1) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref048" target="_blank">48</a>].…”

CARDIOVASCULAR RESPONSES AFTER ISOMETRIC HANDGRIP EXERCISE AT DIFFERENT INTENSITIES IN HEALTHY MEN by Igor Marcelino da Silva (6674021)

“…None of the experimental sessions promoted statistically significant changes in systolic and diastolic BP (p> 0.05 for all). After S50, there was a smaller increase in SDNN five minutes after the exercise (S50: +5±6, S30: +20±5, SC: +10±2 ms, p <0.05) and higher LF/HF after 20 minutes (S50: +1.59±0.80, S30: -0.49±0.49, SC: +0.39±0.49, p <0.05) compared to the other sessions. …”

Ketamine reduces cell adhesion. by Claire E. Hills (452020)

“…<p>AFM-single-cell force spectroscopy was used to measure the detachment energy (fJoules) and maximum unbinding force (nN) required to uncouple two HK2 cells. The energy required to separate the cells; grey area in panel A (control cells), panel B (0.1 mg/mL Ketamine treated cells), panel C (0.5 mg/mL Ketamine treated cells), and panel D (1 mg/mL Ketamine treated cells), and maximum force of detachment (red circle) was measured. …”

S4 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S1 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S3 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S2 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S5 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Stable swimming of wildtype. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Unstable swimming of mutant. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

MO-SAM segmentation performance using the Grid method in arid/semi-arid landscape. by Qitong Wang (15279695)

“…The point prompts, annotations, pixel intervals, and predictions are shown in light blue and the PI is 50, 35, 20; the IoU scores from left to right are 83.99, 81.05, and 44.19 percent, indicating a decrease in performance as the number and density of gridded point prompts increases In the third row, Platinum Group Elements, the point prompts, annotations, pixel intervals, and predictions are shown in purple. …”

Age-dependent changes in biometrics indicate senescence in the European Blackbird <i>Turdus merula</i> by Piotr Piliczewski (5277803)

“…<p><b>Capsule:</b> A 19-year study of European Blackbirds <i>Turdus merula</i> confirms that senescence is associated with a decrease in condition measured by wing length but bills become progressively longer with age.…”

Histological staining of the nerve three days after the surgery. by Bo Ra Kim (9662570)

“…<p>(A) Double staining of neurofilament (NF) and p75^NTR (scale bar, 50μm). …”

Supplementary file 2_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.docx by Yasuhiro Shimojima (4615840)

“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”

Supplementary file 1_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.pptx by Yasuhiro Shimojima (4615840)

“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”