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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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MMR mutants show decreased mating-type silencing.
Published 2020“…<b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”
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Genes whose expression was decreased by 1 mM ouabain by more than 2-fold.
Published 2019“…<p>Genes whose expression was decreased by 1 mM ouabain by more than 2-fold.</p>…”
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GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>.
Published 2024“…<p>GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>.…”
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Tun increases mitochondrial fission, inflammatory cell infiltration, and decreased ER-mitochondria interaction in neonatal rat lungs.
Published 2022“…The decreased expressions of GRP75 (0.5±0.2-fold, p = 0.006767, n = 5) and acyl-CoA synthetase long-chain family member 4 (ASCL4; 0.3±0.1-fold, p<0.001, n = 5) indicate a decreased interaction between ER and mitochondria by Tun. …”
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