Light pulses are sufficient to mimic burst firing of dopamine (DA) neurons <i>in vivo</i>. by Matthew T. C. Brown (358120)

“…<p>(<b>A</b>) Representative single unit recording (above) and peristimulus time histogram (below, 5 ms bins) of a VTA DA neuron during a single light pulse (black markers; 4 ms, one sweep every 2 s) (n = 7). …”

Effects of MTP knockdown on lipid droplet size and distribution. by Larry L. Swift (782762)

“…<p>(A) Lipid droplet size in white fat from control and knockdown mice was determined as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0181046#pone.0181046.g005" target="_blank">Fig 5</a>. …”

DataSheet_1_In Vivo Characterization of Cortical and White Matter Microstructural Pathology in Growth Hormone-Secreting Pituitary Adenoma.pdf by Taoyang Yuan (8470440)

“…</p>Results<p>Compared to controls, we found 1) acromegaly had significantly increased cortical thickness throughout the bilateral cortex (pFDR < 0.05). 2) T1/T2-weighted ratio in the cortex were decreased in the bilateral occipital cortex and pre/postcentral central gyri but increased in the bilateral fusiform, insular, and superior temporal gyri in acromegaly (pFDR < 0.05). 3) T1/T2-weighted ratio were decreased in most bundles, and only a few areas showed increases in acromegaly (pFDR < 0.05). 4) Neurite density index (NDI) was significantly lower throughout the cortex and bundles in acromegaly (pTFCE < 0.05). 5) lower fractional anisotropy (FA) and higher mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD) in extensive bundles in acromegaly (pTFCE < 0.05). 6) microstructural pathology in the cortex and white matter were associated with neuropsychological dysfunction in acromegaly.…”

Plate 4 by Jenna Tomkinson (14757022)

“…</p> <p><br> There are 4 channels/stains:<br> - <strong>DAPI</strong> (DNA/Nuclei)<br> - <strong>GFP</strong> (ER)<br> - <strong>CY5</strong> (Mitochondria)<br> - <strong>RFP</strong> (Actin)<br> <br> There are NF1 Null and WT cells on this plate, with only the WT cells either not treated or treated with one of three siRNA constructs to decrease neurofibromin production using a dose curve.…”

Dendritic length of neurones was nearly constant in the rostromedial half of nucleus laminaris. by Jeremy Corfield (68936)

“…In D, median dendritic lengths for all cells located in a 10×10 µm square (n = 1 to 5) are plotted as a flat topographical map and colours represent dendritic lengths as shown in the legend. …”

Parameter sweep analysis of the Schlögl model. by Marco S. Nobile (541501)

“…<p>Results of a PSA-1D on the Schlögl model, in which the value of the stochastic constant is varied in the interval (the set of reactions and the values of all other parameters are given in Tables 4 and 5 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091963#pone.0091963.s001" target="_blank">Text S1</a>). …”

Time course of <i>K</i>. <i>pneumoniae</i> susceptibility to CHX. by Stephen Buxser (11302550)

“…Details of linear regression parameters are given in S5 Table in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0256336#pone.0256336.s003" target="_blank">S2 Appendix</a>. …”

Table1_Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.docx by Yuqi Xia (11575009)

“…Nevertheless, M2 macrophage infiltration increased in early stages (day 6) and decreased as kidney stones progressed (day 12). Furthermore, treatment with 0.25 and 0.5 mM of oxalate for 48 h significantly upregulated NEAT1, PVT1, CCL7, and ROBO2 expression levels and downregulated hsa-miR-23b-3p, hsa-miR-429, and hsa-miR-139-5p expression levels in the HK-2 cell line in a dose-dependent manner.…”

Image1_Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.TIF by Yuqi Xia (11575009)

“…Nevertheless, M2 macrophage infiltration increased in early stages (day 6) and decreased as kidney stones progressed (day 12). Furthermore, treatment with 0.25 and 0.5 mM of oxalate for 48 h significantly upregulated NEAT1, PVT1, CCL7, and ROBO2 expression levels and downregulated hsa-miR-23b-3p, hsa-miR-429, and hsa-miR-139-5p expression levels in the HK-2 cell line in a dose-dependent manner.…”

Results from an ANOVA conducted to determine the significance of fixed effects on the final linear mixed-effects model (without interactions) of log-denitrification. by Si-Yi Wang (209728)

“…<p>Note: While nosZ ordination axis 3 was not a significant term, its removal increased AIC (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022972#pone.0022972.s005" target="_blank">Table S5</a>) and decreased pseudo-R², so we kept the term in the final model.…”

Gas–Liquid–Solid Migration Characteristics of Gas Hydrate Sediments in Depressurization Combined with Thermal Stimulation Dissociation by Chuanxiao Cheng (6898661)

“…Pressure compensation was first employed to study sediment recovery features. The expansion rate of a porous medium layer under combined dissociation and different backpressure (4.5, 3.5, 2.5, 1.5, and 0.1 MPa) was discussed. …”

Hit expansion around chloroxine. by Sam Barker (4832121)

“…This modification causes a significant decrease in this compound’s activity as a co-treatment with ceftazidime, with a <i>p</i>IC50 ≈ 3.4. 5,7-dichloro-2-methyl-8-quinolinol differs from chloroxine by addition of a methyl group in the 2-position (B). …”

HPV-16 E7 influences the balance between oxidized and reduced GSTP1. by Anna M. Mileo (258322)

“…In the first case, detection was performed after a 90 min or 5 h recovery period, while in the second case detection was performed after a 6 h period. …”

Ten daily doses of ethanol exposure reduced neurogenesis in hippocampal dentate gyrus during combined ethanol and LPS treatments by Liya Qin (46555)

“…(A) Ethanol (5 g/kg, i.g., 1 day) pre-treated group, LPS did not show a decrease in the number of PCNA and doublecortin-IR cells. …”

The MOA D2 surface recognition signal is trypsin sensitive. by Ellen Inga Bruske (3374342)

“…Trypsinisation resulted in a significant decrease of the antibody recognition signal (standard errors are given, p = 0.05 for ΔE5E2 (n = 4) and p = 0.003 (n = 3) for D2) in both cell lines. …”

Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... by Yanmo Cai (22235563)

“…Pathological staining showed reduced renal tissue damage in mice, and electron microscopy revealed reduced pedunculopontine fusion and basement membrane thickening. YSHS decreased GRP78, PERK, p-PERK, CHOP, and Bax proteins and mRNA levels in renal tissues and MPC-5 cells (p < 0.05 and p < 0.01) while increasing the expression level of Nephrin protein and Bcl-2 mRNA (p < 0.05 and p < 0.01).…”

DataSheet_1_Low-Dose Acetylsalicylic Acid Reduces T Cell Immune Activation: Potential Implications for HIV Prevention.pdf by Julie Lajoie (204002)

“…At the genital tract, ASA use correlated with a decreased of activated CD4⁺T cells [CD4⁺CCR5⁺CD161⁺ (p=0.02) and CD4⁺CCR5⁺CD95⁺ (p=0.001)].…”

DataSheet_1_Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer.pdf by Gulcin Tezcan (3337398)

“…Nigericin and a combination of LPS/Nigericin decreased the cell viability and proliferation. …”

DataSheet_2_Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer.pdf by Gulcin Tezcan (3337398)

“…Nigericin and a combination of LPS/Nigericin decreased the cell viability and proliferation. …”

Different conformational changes of sRNA Pab21 and Pab91 are associated with the sequential binding of the sRNP proteins. by Jean-Baptiste Fourmann (14570)

“…(<b>E</b>) Quantification of the decrease in the peak amplitude of the specific RNA positive signal at the λ_max wavelength, generated exclusively by addition of L7Ae to different aCBF5–aNOP10–sRNA complexes. …”