Image_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_4_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIFF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion by Brian P. Carson (187501)

“…Furthermore shRNA-mediated depletion of FIP1 enhanced adiponectin release whereas knock down of FIP5 decreased adiponectin secretion. Knock down of FIP3 had no effect. …”

Metabolic and hemodynamic evaluation of two long term sedation protocols in dogs by D. Regalin (8143476)

“…CaO2, CmvO2, DO2 and VO2 decreased in GCM (5%, 16%, 31% and 7% respectively) and GMF (4%, 19%, 26% and 15% respectively). …”

High-resolution SEM analysis of tip links. by Kateri J. Spinelli (293686)

“…(e, f) Bundles treated with 5 mM EGTA for 5 min showed a marked decrease in bundle Fluo-4 fluorescence and a significant reduction in the number of tip links (g, h). …”

DataSheet_1_Clinical evaluation of bacterial DNA using an improved droplet digital PCR for spontaneous bacterial peritonitis diagnosis.docx by Hao-Xin Wu (13263747)

“…</p>Results<p>After the removal of free DNA, the bactDNA detected by ddPCR was generally decreased (1.75 vs. 1.5 log copies/µl, P < 0.001). …”

The <i>I</i>_K1/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat by Xu-Wen Zhai (4033601)

“…However, clinical anti-arrhythmic agents that primarily act on RMP by enhancing the <i>I</i>_K1 channel are not currently available. We hypothesized that zacopride, a selective and moderate agonist of the <i>I</i>_K1/Kir2.1 channels, prevents and cures acute ischemic arrhythmias. …”

Properties of the optimal force selection model. by Nicolas Borderies (9510718)

“…<b>C2</b>: increase of K_e (sensitivity to effort) leads to decrease of optimal value and decrease of optimal force with a collapse to zero-force when the optimal value becomes negative. …”

Reproductive phenology and germination of Eleocharis laeviglumis R. Trevis. & Boldrini (Cyperaceae) by Camila Luisa Bernhardt Demeda (5765687)

“…We also tested seed germinability and vigor for a period of four months during a single reproductive season. …”

Diffusive dynamics of white player’s advantage. by Haroldo V. Ribeiro (277883)

DataSheet1_PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo.docx by Alexia Chauzy (12247643)

“…The IE was modeled as a decrease of 32% in the in vivo PMB bactericidal effect when the starting inoculum increases from 10⁵ to 10⁷ CFU/thigh. …”

Table_2_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.XLSX by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”

Table_3_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.XLSX by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”

Table_1_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.XLSX by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”

Data_Sheet_1_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.pdf by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”

Data_Sheet_2_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.ZIP by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”

Data_Sheet_3_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.ZIP by Magdalena T. Weidner (6689105)

“…In conclusion, next to various behavioral alterations, we identified gene expression and DNA methylation profiles to be associated with TPH2 inactivation and its interaction with MS, suggesting a gene-by-environment interaction-dependent, modulatory function of brain 5-HT availability.…”