PIK3CA promoter activity in SKOV3 (p53 deficient) tumor xenograft model after cisplatin treatment. by Snehal M. Gaikwad (279479)

“…Mouse from control and treated group exhibited specific [Fig. 4a3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 4a3 (post-treatment)].…”

Methylation Analysis of CpG Orphans by Nicholas C Wong (14627)

“…CpG dinucleotides that are putative MeCP2-binding sites are indicated by solid diamonds. Upon treatment with 5-aza-dC, a number of CpG orphans (Op-4, Op-9, Op-11, Op-12, Op-17, and Op-18) demonstrated a significant decrease in DNA methylation.…”

PTZ increased exploratory behavior in entrained animals during memory tests. by Norman F. Ruby (263642)

“…<p>Arm entries and exploration times for animals from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072433#pone-0072433-g005" target="_blank">figure 5</a>. …”

Schematic of the reaction observed in real time with the 8-spot smFRET setup. by Antonino Ingargiola (2993055)

“…Complementary DNA strands are labeled at DNA promoter bases with donor (D, green, position -5) and acceptor (A, red, position -8) dyes. After formation of a transcription initiation bubble, the dyes are separated, resulting in medium FRET. …”

Ternary Potassium Single Cation Ionic Liquids Explored by Bayesian Optimization by Longjie Liu (21077295)

Tumour growth results. by Ahmed El Kaffas (552465)

“…Combined USMB+XRT+Dll4 mAb was observed to induce the greatest response, with a decrease in tumour size at 5 days after treatment, followed by growth inhibition lasting for nearly 15 days. …”

DNA fluorescent <i>in situ</i> hybridization confirms the presence of VZV genomes in nuclei of hESC-derived neurons quiescently infected with VZV. by Amos Markus (749748)

“…(C) FISH for VZV genomes in quiescently infected neurons receiving the PI3K inhibitor LY as a reactivation stimulus. After LY treatment there was a slight decrease in the percentage of FISH+ nuclei in the preparations, but 25% of labeled nuclei contained 2 or more puncta, suggesting additional sites of VZV genomes had appeared. …”

Normalized total loss on the Facebook dataset (DCOR with and without RLC). by Hossein Rafieizadeh (22676722)

“…This normalization emphasizes relative convergence behavior (shape and stability) rather than raw magnitudes: with RLC, the total objective continues to decrease in late epochs, whereas without RLC it plateaus, consistent with the ablation trends in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0335135#pone.0335135.t005" target="_blank">Table 5</a>.…”

Relationship between computational time and structure size for different algorithms used in the GNM analysis by Lee-Wei Yang (64052)

“…The computation of the 101 slowest modes using (red squares) exhibits a power law of = 5.9 × 10 . Using the latter two methods sequentially results in a dramatic decrease in computing time without loss of accuracy. …”

The expression of PGC-1α and mitochondrial alteration in Myc-ON mice. by Hyoung-gon Lee (73934)

“…Morphometric analysis demonstrated about 2.5 fold increase of mitochondria number and about 30% decrease of mitochondrial size in the cardiomyocytes of Myc-ON mice (p<0.05) compared with Myc-OFF mice (F). n: nucleus, m: myofibrils, mito: mitochondria. …”

Effect of atorvastatin on HMGB1 and IL-8 levels in HUVEC supernatants. by Alexandre W. S. de Souza (556095)

“…HMGB1 intensity in supernatants increases 8 hours after stimulation and a peak is observed at 24 hours with a decrease at 48 hours. 2B and C – HMGB1 and IL-8 levels are significantly higher at 24 hours in supernatants from HUVEC treated with LPS in comparison to unstimulated HUVEC while pre-incubation with 5 µM atorvastatin followed by LPS stimulation lowered HMGB1 and IL-8 levels significantly at 24 hours in HUVEC's supernatants. …”

Crude glycerol in diets for Nile tilapia in the fattening stage by Lilian Dena dos Santos (7368332)

“…Two hundred Nile tilapia (190±4.5 g) were distributed in 20 tanks, in a completely randomized design. …”

Summary of results & proposed feedback model. by Rainer Machné (160042)

“…<p>7A: temporal flow of expression and functional relationships of cluster transcripts in the 0.7 h system (left to right) and the 5 h system (top to bottom). 7B: summary of observed properties (significant enrichment or biases) of the main gene clusters. 7C: Potential regulatory interactions of broad cellular functionality <i>via</i> the energetic status of the cell, reflected, <i>e</i>.g., in ATP:ADP ratios. …”

Blood pressure documentation in the emergency department by Ana Carolina Queiroz Godoy Daniel (4650613)

“…Of these measures, 46.5% were abnormal. The mean time from admission to documentation of the first blood pressure measurement was 2.5 minutes, with 42 minutes between subsequent measures. …”

Predicted miRNAs are expressed in C2C12 cells and skeletal muscle and can target the utrophin 3′-UTR. by Utpal Basu (190371)

“…All six miRNAs are expressed in C2C12 cells. miR-150 was not detected (n.d.) in TA, while miR-296-5p was n.d. in TA or soleus. Bars represent mean ± SD. …”

AZD1480 leads to TPC-1 xenograft tumor remission. by Joana P. Couto (130525)

“…Following tumor engraftment (∼0.5 cm³), mice were distributed into four groups (n = 5/group) with similar mean tumor volumes. …”

The Laminin Response in Inflammatory Bowel Disease: Protection or Malignancy? by Caroline Spenlé (161321)

“…Here we showed first that in human IBD colonic samples and in murine colitis the LMα1 and LMα5 chains are specifically and ectopically overexpressed with a concomitant nuclear p53 accumulation. …”

PLYOMETRIC TRAINING IMPROVES SWIMMING PERFORMANCE IN RECREATIONALLY-TRAINED SWIMMERS by Rodrigo Cañas-Jamett (10403402)

“…In addition, sit-and-reach flexibility and squat jump tests were conducted, as well as a 200m swimming trial. Results: Two-way ANOVA with post-hoc analysis revealed an increase in sit-and-reach flexibility (PRE: 4.5±5.3 cm; POST: 10.9±5.9 cm, p<0.01) and squat jump height (PRE: 24.9±3.7 cm; POST: 28.3±4.2 cm, p<0.01) and a decrease in 200m-swimming time (PRE: 220±26.5 sec; POST: 204±24.4 sec, p<0.01) for the PTG only. …”

Effects of acute leptin suppression on activity in Tet-off hyperleptinemic transgenic <i>obob</i> mice. by Ana C. Ribeiro (210764)

“…(<i>F</i>) Leptin suppression also significantly decreased RWA in Tg <i>obob</i> (n = 5) although at a slower rate becoming significant at day 20 (p<0.05). …”

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, “GENEREPOL study”: Lack of common variants with large effect sizes by Joe-Elie Salem (4351000)

“…QTc and TpTe increased by 5.5±3.5% and 15±19.6%, respectively, and TAmp decreased by 13.2±15.5%. …”