Depletion of TPX2 causes defects in 53BP1 ionizing radiation-induced foci formation. by Gernot Neumayer (77179)

“…(B) Doxycycline-induced expression of TPX2 miRNA significantly decreases the percentage of HeLa cells with more than five 53BP1 ionizing radiation-induced foci 15 min to 2 h after 2 Gy when compared to non-induced controls (Ctrl). …”

SDS pancreas senescence is downstream of p53-dependent changes in protein synthesis. by Marina E. Tourlakis (751986)

“…<p><b>A,</b> Increased nuclei per acinar area (*<i>P</i> = 0.029, Wilcoxon Rank Sum Test) and <b>B,</b> decreased mean acinus diameter (**<i>P</i> = 0.0073 and <i>NS</i> = not significant, <i>P</i> = 0.142; unpaired, two-sided T-test) in <i>Sbds</i>^{<i>P–/R126T</i>}; <i>Trp53</i>^{<i>–/–</i>}pancreas at 30 days of age. …”

Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation-5 by Rebecca A Howard (78819)

Image_2_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.tif by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Expression of AC5 and AC6 in WT and AMPKα2-/- mice. by Anne Garnier (130125)

Image1_Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.JPEG by Dan Sun (140898)

“…Furthermore, the treatment of lidocaine repressed tumor growth of ovarian cancer cells in vivo, in which the miR-382-5p expression was increased while SLC7A11 expression was decreased. …”

Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chan... by Tingting Liu (267387)

“…</p><p>Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chang >1.5).…”

<i>mMgat2</i> and <i>HuMgat2</i> mice become obese when fed a HFD. by J. Jose Corbalan (22439198)

Recombinant CCR5-T4L acts as a HIV-1 co-receptor and down-regulates WT-CCR5 expression on the 3T3T4 cell surface. by Qingwen Jin (767337)

“…The averaged mean fluorescence values (MFVs) for CCR5 from three experiments are plotted as a bar diagram, where WT-CCR5 expression after transfection with WT-CCR5 plus empty vector is set at 100. …”

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…Glucocorticoid-induced effects were attenuated by glucocorticoid-inducible kinase 1 (SGK1) inhibitor GSK650394, which also inhibited glucocorticoid induced phosphorylation of Forkhead box O3a (FOXO3a). Furthermore, glucocorticoid-induced down-regulation of GR was mimicked by the inhibition of AMPK and abolished by the AMPK activators or the histone deacetylase 5 (HDAC5) inhibitors. …”

Hypoxic MSCs maintain stemness properties. by Rohini L. Kadle (4919335)

Effects of metformin on depressive behavior and expression of GR in prefrontal cortex of rat after chronic exposure to CORT. by Shi-Ying Yuan (2937669)

Expression analysis in strain B728a of three FecI-like ECF σ factor genes (<i>ecf5</i>, <i>ecf7</i>, and <i>ecf6</i>) and associated putative iron-responsive genes in low and high... by Poulami Basu Thakur (389600)

Source data for Figs 1E, 2E, 2G, 3B, 3D, 3H, 5D, 6B, 6E, 7B, 7E, S1A, S1B, S1C, S3B, S4, S5B, S5D, S6, S7B, S7D, S10B, S10C, S11B, S11C, S12B, and S12D. by Yongle Zhang (11355546)

Field evaluation of orange rust reaction and genotyping of molecular markers for the <i>G1</i> gene in a nuclear collection of 299 sugarcane accessions. by Gleicy Kelly Oliveira (19259604)

Model predicted OAE prevalence as a function of total mf prevalence compared with the original survey data obtained from Pion et al. [16]. by Samit Bhattacharyya (173222)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

Characteristics of 37 included studies regarding smoking and risk of dementia. by Guochao Zhong (701289)