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23881
EGFR Signaling Regulates Maspin/SerpinB5 Phosphorylation and Nuclear Localization in Mammary Epithelial Cells
Published 2016“…<div><p>Maspin (SerpinB5) is a non-inhibitory serpin (<u>ser</u>ine <u>p</u>rotease <u>in</u>hibitor) with very diverse biological activities including regulation of cell adhesion, migration, death, control of gene expression and oxidative stress response. …”
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23882
DMOG treatment affects worm body morphology in a dose-dependent manner.
Published 2019“…Measurements were normalized to untreated worm measurements. A Dunnett’s test was used to compare mean morphological characteristics of DMOG-treated to untreated worms. …”
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23883
Relationship between OLT and soil temperature at 50-cm (a), the depth at which charcoal was measured (b), and the active layer depth (c) measured in the field for a subset of the d...
Published 2013“…Each point represents the mean of at least five observations at the specified organic layer depth. …”
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23884
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23885
Luminescent biosensors of authentic SARS-CoV-2 infection.
Published 2022“…<p>(<b>A</b>) Activation of luciferase-based reporters by recombinant SARS-CoV-2 protease expression. …”
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23886
Framework Reduction and Alkali-Metal Doping of a Triply Catenating Metal−Organic Framework Enhances and Then Diminishes H<sub>2</sub> Uptake
Published 2009“…A permanently microporous metal−organic framework compound with the formula Zn<sub>2</sub>(NDC)<sub>2</sub>(diPyTz) (NDC = 2,6-naphthalenedicarboxylate, diPyTz = di-3,6-(4-pyridyl)-1,2,4,5-tetrazine) has been synthesized. …”
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23887
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23888
Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea
Published 2017“…In this study, activity-guided isolation identified four flavonoids <b>1-4</b> (apigenin, luteolin, chrysoeriol, quercetin) from <i>Vernonia cinerea</i> and <i>Pluchea indica, </i>four hirsutinolide-type sesquiterpene lactones <b>5-8</b> from <i>V. cinerea</i>, and acetylenic thiophenes <b>9-11</b> from <i>P. indica</i> that inhibited CYP2A6- and CYP2A13-mediated coumarin 7-hydroxylation. …”
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23889
Net-square displacement (NSD) plot for each migration cycle of each individual Tibetan antelope (<i>Pantholops hodgsonii</i>) (individual ID_year).
Published 2019“…<p>The NSD plot represents the distance to the starting point (wintering sites) where Antelopes stay at the beginning of a calendar year. …”
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23890
Sod2<sup>-/-</sup> erythroid development is characterized by a maturational left shift.
Published 2011“…<p><b>A</b>. Sod2<sup>-/-</sup> marrow (right) shows an increased fraction of immature basophilic erythroblasts (R4 gate: 1.9-fold increase) and decreased numbers of reticulocytes and mature RBC (R7 gate: 6-fold decrease), respectively, relative to Sod2<sup>+/+</sup> (left). …”
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23891
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23892
Metabolic effects of exposure to AmB in <i>L</i>. <i>mexicana</i> promastigotes cultured in HOMEM and DM.
Published 2022“…Each line represents one biological replicate (n = 4). Increase (red) or decrease (blue) in fold-change is relative to untreated cells after treatment with AmB at 5 x their EC<sub>50</sub> values for 15 mins. …”
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23893
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23894
Intervention Scenario with Limited AV Supplies: Schematic Representation of the Implemented Containment Strategies and Corresponding Probability of Global Outbreaks, for a Pandemic...
Published 2013“…The assumed protocol considers a rate distribution <i>p<sub>AV</sub></i> = 0.5/d, whenever AV stockpiles are available. …”
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23895
Gray matter atrophy 5 weeks after stepwise BCCAo.
Published 2018“…<p>Blue-to-light-blue and red-to-yellow colors represent decreased and increased gray matter density 5 weeks after the BCCAo compared to baseline measurements, respectively (the treatment groups were pooled: n = 27 and n = 26, voxel-wise permutation test). …”
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23896
Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor
Published 2016“…Here, by deconstructing potent PRMT inhibitors, we find that chemical moieties occupying the substrate arginine-binding site can act as efficient fragment inhibitors. Screening a fragment library against PRMT6 produced numerous hits, including a 300 nM inhibitor (ligand efficiency of 0.56) that decreased global histone 3 arginine 2 methylation in cells, and can serve as a warhead for the development of PRMT chemical probes.…”
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23897
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23898
Data_Sheet_1_Probiotics for the prevention and treatment of COVID-19: a rapid systematic review and meta-analysis.docx
Published 2023“…We conducted our meta-analysis using RevMan 5.4 with risk ratio (RR) and mean difference (MD) as the effect measures.…”
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23899
miR-135b negatively regulates SMAD5 expression.
Published 2013“…(B) miR-135b is confirmed to target SMAD5 in hMSCs. Transfection with miR-135b inhibitor or mimic leads to an increase or a decrease of SMAD5 expression, respectively, by Western blot in hMSCs. …”
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23900
Table_1_Treatment of multiple sclerosis with rituximab: A Spanish multicenter experience.DOCX
Published 2023“…After a median follow-up of 14.2 months (IQR: 6.5–27.2), ARR decreased by 85.7% (p < 0.001) and GEL by 82.9%, from 0.41 to 0.07 (p < 0.001). …”