Increase of T cell presence in the liver of PD-1-deficient mice infected with <i>S</i>. <i>japonicum</i> for 8 weeks. by Liaoxun Lu (179293)

Results of bivariate and multivariable survey-weighted logistic regression for the association between children’s nutritional status in first 5 years and their physical growth at a... by Apurv Soni (7429826)

Distinct Lipid A Moieties Contribute to Pathogen-Induced Site-Specific Vascular Inflammation by Connie Slocum (596261)

“…In contrast, a <i>P. gingivalis</i> strain producing exclusively agonistic lipid A augmented levels of proinflammatory mediators and activated the inflammasome in a caspase-11-dependent manner, resulting in host cell lysis and decreased bacterial survival. …”

Supplementary Material for: Increased Quinolone-Resistant Mutations of gyrA and parC Genes after Pouchitis Treatment with Ciprofloxacin by Fukushima K. (4865416)

“…We successfully quantified mutation rates at <i>gyrA</i> 83 and 87, and at <i>parC</i> 84, all of which were significantly higher in samples from CFX-treated patients (70, 84, and 38%) than from CFX-untreated patients (13, 11, and 5%). …”

Negative selection on reassortment. by Mara Villa (2855789)

“…<p>(a) The cumulative distribution of mean nucleotide distances <i>d</i> between reassortant and parent strains for the HA-NA reassortments in influenza A/H3N2 (red line) is compared to the corresponding distribution of distances for co-circulating strains in the same influenza season (solid blue line) and from the New York area only [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006685#ppat.1006685.ref028" target="_blank">28</a>] (dashed blue line). …”

Reduced histone H3 in nucleus and chromatin in the <i>unc-85</i> mutant embryos. by Ruixue Zhao (2744689)

Characterization of 39 independent isolated mutants with increased frameshifting activity caused by increased geranylation activity following localized mutagenesis of the <i>mnmH</... by Gunilla Jäger (399541)

“…All these mutants have increased +1 frameshifting activity (data not shown), which is a caused by increased geranylation of tRNA. We did not observe a simple correlation between ability to suppress a +1 frameshift mutation to the level of cmnm⁵ges²UpU, which might not be expect, since induction of frameshifting is complex although partly dependent on a decreased level of charged Gln- [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153488#pone.0153488.ref004" target="_blank">4</a>]. …”

CRAI with 5-Fu and Octreotide (Oct) attenuated serum parameters of pancreatitis. by Meng Tao Zhou (321534)

“…<p>Three treatment groups have lower serum levels of amylase activity, TNF-α and BUN as compared to the SAP group at different time points. The combined use of 5-Fu and Oct significantly decreased the levels of amylase activity as compared to single use of 5-Fu or Oct. …”

<i>Drosophila</i> Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling by Einat Cinnamon (2922108)

“…Several enzymes of fatty acid, triglyceride and hydrocarbon metabolism are required in oenocytes primarily for lipid droplet induction rather than for cell growth. In contrast, a very long chain fatty-acyl-CoA reductase (FarO) and a putative lipid dehydrogenase/reductase (Spidey, also known as Kar) not only promote lipid droplet induction but also inhibit oenocyte growth. …”

Uvrag in Tregs is dispensable for establishment of immune tolerance and eTreg accumulation. by Erienne G. Norton (9612079)

Targeting of Vps34 or Atg14, but not Uvrag, in Tregs reduces tumor growth in mouse models. by Erienne G. Norton (9612079)

<i>In planta</i> experiments on two different tomato plant cultivars. by Set Madian Perez (6786653)

Noise-induced transition to bistable behaviour. by Tomás Alarcón (224873)

Foxp3 expression in wildtype mice with 8 weeks of <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

Attenuation of bleomycin-induced lung fibrosis upon anti-IL-17A treatment. by Paméla Gasse (209357)

“…Collagen content enhanced after BLM was significantly reduced when the mice were treated with anti-IL-17A antibody (D). Data represent mean values ± SD from 2 independent experiments (n = 5 mice per group; *, <i>p</i><0.05; ***, <i>p</i><0.001). …”

<i>P</i>, <i>N</i>, <i>D</i>, and <i>C</i> versus time for model (1) with 20 sets of randomly selected parameters with the same initial conditions. by Manuel Mai (497861)

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes by John R. Cashman (354526)

“…Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (I_NaL) SCN5A mutations that prolongs cardiac action potential (AP) and enhances I_NaL current. …”

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells by David A. Tumbarello (680437)

“…Conversely, overexpression of SPARC increased TGFBI deposition. A SPARC-YFP fusion construct expressed by the Met5a cell line co-localized with TGFBI in the cell-derived ECM. …”

PD-1 deficiency suppresses Th2 differentiation and promotes IFN-γ production in liver T cells of the <i>S</i>. <i>japonicum</i> infected mice. by Liaoxun Lu (179293)

Myoendothelial and/or endothelial gap junctions participate to the calcium and contractile responses to 5-HT. by Marie Billaud (261506)

“…<p>Typical traces of simultaneous recordings of intracellular calcium (top panel) and contraction (bottom panel) induced by 5­HT 10 µM are shown in A. 300 µM ^37-43Gap 27 was introduced into the bath where indicated. …”