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42441
Solution and Solid-State Structure of 2- and 4-Bis(trimethylsilyl)methylpyridinium Cations
Published 2020“…N-Methylation of the 2- and 4-bis(trimethylsilyl)methyl pyridines <b>7</b> and <b>9</b> gives the ions <b>5</b> and <b>6</b> and results in a significant decrease in the <sup>13</sup>CH−<sup>29</sup>SiMe<sub>3</sub> coupling constant, consistent with increased C−Si−π hyperconjugation between the trimethylsilyl substituents and the electron-deficient aromatic system of the pyridinium cations. …”
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42442
Solution and Solid-State Structure of 2- and 4-Bis(trimethylsilyl)methylpyridinium Cations
Published 2020“…N-Methylation of the 2- and 4-bis(trimethylsilyl)methyl pyridines <b>7</b> and <b>9</b> gives the ions <b>5</b> and <b>6</b> and results in a significant decrease in the <sup>13</sup>CH−<sup>29</sup>SiMe<sub>3</sub> coupling constant, consistent with increased C−Si−π hyperconjugation between the trimethylsilyl substituents and the electron-deficient aromatic system of the pyridinium cations. …”
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42443
Solution and Solid-State Structure of 2- and 4-Bis(trimethylsilyl)methylpyridinium Cations
Published 2020“…N-Methylation of the 2- and 4-bis(trimethylsilyl)methyl pyridines <b>7</b> and <b>9</b> gives the ions <b>5</b> and <b>6</b> and results in a significant decrease in the <sup>13</sup>CH−<sup>29</sup>SiMe<sub>3</sub> coupling constant, consistent with increased C−Si−π hyperconjugation between the trimethylsilyl substituents and the electron-deficient aromatic system of the pyridinium cations. …”
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42444
Solution and Solid-State Structure of 2- and 4-Bis(trimethylsilyl)methylpyridinium Cations
Published 2020“…N-Methylation of the 2- and 4-bis(trimethylsilyl)methyl pyridines <b>7</b> and <b>9</b> gives the ions <b>5</b> and <b>6</b> and results in a significant decrease in the <sup>13</sup>CH−<sup>29</sup>SiMe<sub>3</sub> coupling constant, consistent with increased C−Si−π hyperconjugation between the trimethylsilyl substituents and the electron-deficient aromatic system of the pyridinium cations. …”
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42445
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42446
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42447
Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation
Published 2016“…The results showed that transient and stable overexpression of heparanase in HepG2 cells caused a reduction of hepcidin expression and of SMAD5 phosphorylation. …”
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42448
Stage call: Cardiovascular reactivity to audition stress in musicians
Published 2017“…The complexity science approaches—namely, multiscale sample entropy and multiscale fuzzy entropy—indicated a statistically significant decrease in structural complexity in HRV from the low- to the high-stress condition and an increase in structural complexity from the pre-performance to performance period, thus confirming the complexity loss theory and a loss in degrees of freedom due to stress. …”
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42449
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42450
Creation of a statistical shape model (SSM) of the breast.
Published 2020“…Again we get shapes where each point is in correspondence to each other and we are able to define the covariance matrix which is essential generating a SSM. …”
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42451
Nematode survival and transcription of <i>aidA</i>.
Published 2013“…OHL was added at 8 h (arrow). <i>aidA</i> expression was: significantly decreased in K56-2ΔM1871 compared to that in K56-2 from 29.5–42.5 h (p<0.05) (most timepoints); significantly increased in K56-2ΔM1871 300 ρM OHL compared to that in K56-2 from 30–41 h (p<0.001).…”
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42452
P1<sup>SCSMV</sup> directly binds to the stem-loop region of <i>NbbZIP60U</i> through via NLS region <i>in vitro</i>.
Published 2023“…<p><b>(A).</b> CBB staining of the purified recombinant GST-tagged GFP, P1<sup>SCSMV</sup>, and P1<sup>SCSMV</sup>-nls mutant. …”
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42453
NSP1 affects host-cell transcription of immune-related genes via H3K9me2.
Published 2024“…<b>C</b>.) Bar graph of log2Fold change values in RNA-Seq data of WT versus NSP1 K164A/H165A transfected A459 cells after scramble or PRRC2B silencing showing restoration of IFNB1 IFNL1 IFNL2 and IFNL3 expression. …”
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42454
How the Sequence of a Gene Specifies Structural Symmetry in Proteins
Published 2015“…Meanwhile, codon usage bias and local mRNA structure might be involved in modulating translation speed for the formation of structural symmetry: a major decrease of local codon usage bias in the middle of the codon sequence can be identified as a common feature; and major or consecutive decreases in local mRNA folding energy near the boundaries of the symmetric substructures can also be observed. …”
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42455
Hepatitis C Virus Frameshift/Alternate Reading Frame Protein Suppresses Interferon Responses Mediated by Pattern Recognition Receptor Retinoic-Acid-Inducible Gene-I
Published 2016“…The potentiation of IFN response by the F/ARFP mutations was diminished in Huh7.5 cells, which already have a defective RIG-I, and by decreasing RIG-I expression in Huh7 cells. …”
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42456
Fraction of phosphorylated Lat as a function of time with phosphatase.
Published 2012“…<b>(C)</b> The effect of decreasing the concentration of phosphatase. Results are shown for 5 ZAP-70 and 5 Lat clusters, each of which contains 20 molecules. …”
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42457
Construction of basis filters using a randomly connected network with feed-forward inhibition via a second population mimicking Golgi cells.
Published 2015“…<p>As previously, filters used are <i>τ</i><sub>1</sub> = 10<i>ms</i> (blue), <i>τ</i><sub>2</sub> = 100<i>ms</i> (green) and <i>τ</i><sub>3</sub> = 500<i>ms</i> (red). <b>A,B,C</b>: Goodness of fit (<i>R</i><sup>2</sup>) (<b>A1,B1,C1</b>) and Lyapunov exponents (<b>A2,B2,C2</b>) for three networks with <i>τ</i><sub><i>w</i></sub> = 50<i>ms</i>, <i>τ</i><sub><i>u</i></sub> = 1<i>ms</i> (<b>A</b>), <i>τ</i><sub><i>w</i></sub> = 50<i>ms</i>, <i>τ</i><sub><i>u</i></sub> = 50<i>ms</i> (<b>B</b>) and <i>τ</i><sub><i>w</i></sub> = 50<i>ms</i>, <i>τ</i><sub><i>u</i></sub> = 100<i>ms</i> (<b>C</b>). …”
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42458
Catalytically active USP2a, USP2a<sup>WT</sup>, alters MDM2 and cyclin D1 expression.
Published 2013“…<p>(<b>A</b>) Enforced expression of wild type USP2a (USP2a<sup>WT</sup>) enhances MDM2 level and decreases p53 expression (western blot). …”
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42459
An 82-year-old man with lung cancer.
Published 2017“…(D). On a spectral plot from a MonoE image at 40 keV, peripheral hyperattenuation shows a gradual decrease in HU values with a steep slope (ROI 1) similar to a tumour vessel (ROI 4), suggesting a contrast-enhancing tumour portion. …”
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42460
Osteopontin activates AKT pathway in a subset of GBM.
Published 2011“…In serum-propagated CD44<sup>high</sup> GBM cells, AKT and S6R pathway was activated without ligands stimulation (upper right panel). In CD44v6 knocked-down cells, phosphorylation of AKT and S6R was decreased and OPN stimulation (5 µg/ml, 30 minutes) failed to activate both molecules. …”