miR-126-3p reduces VEGF secretion and endothelial tube formation. by Yin Xiong (342546)

“…<p><b>(A)</b> miR-126-3p overexpression significantly reduced secreted VEGF levels in TPC-1 and FTC-133 cell lines but not XTC-1 cells. * p < 0.5. …”

Impact of antioxidants or H₂O₂ on the mRNA level of <i>ApoB</i>. by Bei Wang (116772)

Model for distinct G-protein modulation of <i>I</i>_<i>Ba</i> and <i>I</i>_<i>Ca</i> mediated by Ca_v2.2. by Jessica R. Thomas (20691419)

“…<p>(A, B) Ca_v2.2 channels are potentiated by PIP2 binding and inhibited by Gβγ binding to the channel. …”

Effect of angiotensin II treatment on NHE8 protein abundance in A549 cells. by Safa Kinaneh (10681332)

“…NHE8 protein abundance, as assessed by western blotting, significantly was decreased following Ang II treatment for 3, 5 (N-3 each) & 24 hours (N-2) (Figures A & B). * P value <0.05 as compared to control. ** P value < 0.01 as compared to control. …”

NINL and DZANK1 associate specifically with complementary subunits of the cytoplasmic dynein 1 motor complex. by Margo Dona (816015)

“…MO-injection of sub-effective concentrations of <i>ninl</i> (0.5 ng/nl) (e-e”) or <i>dync1h1</i> (1 ng/nl) (f-f”) generates larvae with a normal phenotype and normal OS length, compared to wildtype larvae (b-b”) and control MO-injected larvae (c-c”). …”

The 452 registrations of the 750 feature vectors after dimension reduction using the AI algorithm autoencoder, the 6 clusters obtained with the DBSCAN clustering algorithm are colo... by Gerhard Fritsch (405224)

Data_Sheet_5_RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Prima... by Wenwen Si (5956190)

Baseline characteristics of participants. by Meiling Wang (808623)

“…<i>Eggerthella</i>, <i>Coprobacillus</i>, and <i>Peptostreptococcus</i> were abundant in the intestinal tracts of the POP group in preoperative and postoperative infections. There was a decrease in the abundance of beneficial genera such as <i>Blautia</i> and an increase in the abundance of pathogenic or opportunistic pathogens such as <i>Bacteroides.…”

Study design and flow diagram. by Meiling Wang (808623)

“…<i>Eggerthella</i>, <i>Coprobacillus</i>, and <i>Peptostreptococcus</i> were abundant in the intestinal tracts of the POP group in preoperative and postoperative infections. There was a decrease in the abundance of beneficial genera such as <i>Blautia</i> and an increase in the abundance of pathogenic or opportunistic pathogens such as <i>Bacteroides.…”

Table_1_Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and N... by Yee Qian Lee (10727655)

“…Increased caspase-3 activity and decreased bcl-2 concentration upon treatment indicate that MS13 induces apoptosis in these cells in a dose- and time-dependent manner. …”

Genetic perturbation analysis of the stoichiometry control system. by Koji Ishikawa (703501)

“…The untagged dosage-compensated protein was expressed from multicopy plasmid pTOW40836 containing the native regulatory sequences, including promoter and 5´ and 3´ untranslated regions. If the target gene is subjected to dosage compensation, the level of the TAP-tagged target protein expressed only from the chromosome decreases upon an increase in gene copy number (Multi) compared to vector control (Single). …”

Discovery of Potent, Selective, and Brain-Penetrant 1<i>H</i>‑Pyrazol-5-yl‑1<i>H</i>‑pyrrolo[2,3‑<i>b</i>]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors by Makoto Fushimi (1714441)

“…Scaffold hopping and lead optimization of <i>N</i>-(2,4-difluorobenzyl)-3-(1<i>H</i>-pyrazol-5-yl)­imidazo­[1,2-<i>b</i>]­pyridazin-6-amine <b>1</b> guided by a cocrystal structure of compound <b>1</b> bound to ALK resulted in the identification of (6-(1-(5-fluoropyridin-2-yl)­ethoxy)-1-(5-methyl-1<i>H</i>-pyrazol-3-yl)-1<i>H</i>-pyrrolo­[2,3-<i>b</i>]­pyridin-3-yl)­((2<i>S</i>)-2-methylmorpholin-4-yl)­methanone <b>13</b> as a highly potent, selective, and brain-penetrable compound. …”

Bayesian skyride plot (BSP) for the three genomic segments of RVFV. by P. O. Ly Soumaré (169424)

TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes by Müge Akpınar (3815143)

“…TDRD6 deficiency impairs the assembly of spliceosomes, which feature 3.5-fold increased levels of U5 snRNPs. In the nucleus, these deficiencies in spliceosome maturation correlate with decreased numbers of SMN-positive bodies and Cajal bodies involved in nuclear snRNP maturation. …”

Structural maturation of the FC in high pressure frozen cells. by Johanna L. Höög (402710)

Diabetic conditions increases Ephrin-B2 signaling in pericytes. by Maha Coucha (6184880)

Concentration-response curves to acetylcholine (ACh) before/after inhibition of EET formation by PPOH (10 μmol/l) or 17-ODYA (10 μmol/l) in phenylephrine (PE)-preconstricted renal... by Dandan Yin (4373071)

Image 5_Investigation of Tongqiao Huashuan Granules’ effect on hippocampal neuron autophagy in vascular dementia rats via the PI3K/Akt-mTOR signaling pathway using network pharmaco... by Xiaoqu Jiang (20912471)

Assessment of kidney function in the elderly: a population-based study by Marina Constante Dutra (12729314)

“…With regard to the glomerular filtration rate, 26.2% had a normal rate; 60.2% showed a slight decrease; 13.0% a moderate decrease; 0.5% severe kidney function decline; and 0.1% extreme fall. …”

Outcomes of protocolised analgesia and sedation in a neurocritical care unit by Leana Mahmoud (5314205)

“…There was a decrease in fentanyl (cost ratio = 0.8, CLs 0.5, 1.1) and propofol costs (cost ratio = 0.6, CLs 0.5, 0.8). …”