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59981
Identification of the Capzb2 region necessary for binding tubulin and for the effect on tubulin polymerization.
Published 2009“…(F) Tubulin polymerization assay was performed as in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000208#pbio-1000208-g004" target="_blank">Figures 4D</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000208#pbio-1000208-g005" target="_blank">5E</a>, in the presence of 10 µM GST-Capzb2, 10 µM GST-Capzb2Δ106–140, 10 µM GST-Capzb2 C-terminus 141–271, or 10 µM GST-Capza2. …”
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59982
Limiting the amount of growth factors produced by fibroblasts in the no repair (NR) ABM revealed that only a large reduction in TGF-β levels altered the collagen density following...
Published 2021“…A 75% reduction of TGF-β secretion by fibroblasts increased the number of SSCs present and decreased the rate and amount of collagen accumulation (A). …”
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59983
An <i>N</i>,<i>N</i>‑Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C‑Like 2‑Based Therapeutic for Inflammatory Bowel Disease
Published 2016“…The oral treatment with <b>7</b> (8 mg/kg/d) in a mouse model of IBD resulted in lowering the disease activity index, decreasing colonic inflammatory lesions by 4-fold, and suppressing inflammatory markers (e.g., TNF-α, and interferon-γ) in the gut. …”
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59984
EAEC combines with <i>Giardia</i> to enhance microbial host co-metabolic perturbations and co-infection exhausts regulatory host energy expenditure adaptations during malnutrition.
Published 2017“…(C,D) OPLS-DA correlation coefficient plots indicating the variation between (C) <i>Giardia</i> infected (Day 13) and uninfected PBS controls (Day 13) (Q<sup>2</sup>Y = 0.40; P = 0.02) or (D) co-infection (Day 13) versus EAEC mono-infection (Day 13) (Q<sup>2</sup>Y = 0.82; p = 0.001) (n = 4-5/group). Correlation coefficients plots were generated with the use of a back-scaling transformation to display the contribution of each metabolite to the sample classification. …”
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59985
Table1_40Ar/39Ar ages and geochemistry of the Intersalar Range of the Bolivian Altiplano: A volcanological transect spanning the arc and reararc of the Central Andean Plateau.xlsx
Published 2022“…We identify two distinct pulses of reararc magmatism: a Miocene phase between 20 Ma and 14 Ma that corresponds with local compressional shortening, and a Plio-Pleistocene phase between 5 and 1 Ma that postdates observed structural deformation in the region. …”
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59986
Data_Sheet_1_Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabol...
Published 2022“…In both sexes, AEA and other NAEs (including OEA, and PEA) decreased after 6 months (for AEA: −4.9%), whereas the ratio OEA/AEA increased after 1 year (+5.8%). …”
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59987
Table2_40Ar/39Ar ages and geochemistry of the Intersalar Range of the Bolivian Altiplano: A volcanological transect spanning the arc and reararc of the Central Andean Plateau.xlsx
Published 2022“…We identify two distinct pulses of reararc magmatism: a Miocene phase between 20 Ma and 14 Ma that corresponds with local compressional shortening, and a Plio-Pleistocene phase between 5 and 1 Ma that postdates observed structural deformation in the region. …”
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59988
DataSheet_1_Activity of TNT: a phase 2 study using talimogene laherparepvec, nivolumab and trabectedin for previously treated patients with advanced sarcomas (NCT# 03886311).docx
Published 2023“…One patient had a complete surgical resection. Fifty percent of patients had a ≥ grade 3 treatment related adverse events which included anemia (6%), thrombocytopenia (6%), neutropenia (4%), increased alanine transaminase (4%), decreased left ventricular ejection fraction (4%), dehydration (4%), hyponatremia (4%).…”
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59989
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59990
Data Sheet 1_Exploring AI-personalized visualization of the safe place in virtual reality versus imagination of the safe place for stress, burnout, and relaxation in psychotherapis...
Published 2025“…Further, the roles of imagery ability and presence were explored.</p>Methods<p>Five psychotherapists from an outpatient setting participated in a six-week, within-subject study that used an alternating treatments design (ABCABC) which was created via a participatory approach where participants actively engaged in the planning of the study. …”
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59991
Data_Sheet_1_Microbial communities in the liver and brain are informative for postmortem submersion interval estimation in the late phase of decomposition: A study in mouse cadaver...
Published 2022“…Eighteen taxa in the liver which were mainly related to Clostridium_sensu_stricto and Aeromonas, and 26 taxa in the brain which were mainly belonged to Clostridium_sensu_stricto, Acetobacteroides, and Limnochorda, were selected as potential biomarkers for PMSI estimation based on a random forest algorithm. The PMSI estimation models established yielded accurate prediction results with mean absolute errors ± the standard error of 1.282 ± 0.189 d for the liver and 0.989 ± 0.237 d for the brain.…”
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59992
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59993
Treatment with the ILK Inhibitor QLT-0267 Results in Aberrant Cytokinesis and Mitotic Spindle Disorganization.
Published 2014“…<p>(A) A dramatic decrease in F-actin staining was observed in Y79 cells after a 5-day incubation to 10 µM QLT-0267 (n = 4). …”
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59994
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59995
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59996
Performance is temporarily reduced after anoxic coma induced by water immersion.
Published 2014“…(<b>B</b>). The reduction in mean spike count is most prominent at 1 hour of recovery, and gradually returns to control levels over a period of 5 hours. …”
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59997
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59998
Aboveground net primary productivity not CO<sub>2</sub> exchange remain stable under three timing of extreme drought in a semi-arid steppe - Fig 2
Published 2019“…</b> The percentage at the top of the bar represents decreased values of treatments. Data are means±se.</p>…”
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59999
Robotic Bilateral Thymectomy
Published 2023“…First, a chest CT scan was performed, which demonstrated two nodular opacities in the anterior mediastinum, the largest measuring 5.9 mm. …”
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60000