Telomere Lengths, Pulmonary Fibrosis and Telomerase (<em>TERT</em>) Mutations by Alberto Diaz de Leon (248766)

“…Family members within kindreds who do not inherit the <em>TERT</em> mutation have shorter telomere lengths than controls, demonstrating epigenetic inheritance of a shortened parental telomere length set-point.…”

Data_Sheet_1_Data-Driven Modeling of Global Storm Surges.PDF by M. Tadesse (8762661)

“…For extreme events, the average correlation decreases to 0.54 (0.33) and RMSE increases to 14.5 (13.1) cm for extratropical (tropical) regions. …”

Supplementary Tables S1 and S2 by Thomas Clanton (9323303)

“…In the second hour of exposure, though G-CSF, IL-6, KC(CXCL1) and MCP-1(CCL2) were elevated nearly 5-10-fold compared to the first hour, only MCP-1 decreased secretion in LyzMyd88^-/- muscles. …”

Activation of the UPR can override the inhibition of NF-κB by IKK inhibitors in cancer cells with elevated IKK activity. by Arvin B. Tam (124164)

“…A reduction in P-IκBα and increase in total IκBα were seen corresponding to a decrease in IKK activity. …”

Pre-seeded scaffolds promote more effective tissue regeneration. by Paul P. Bonvallet (708039)

“…*Represents p<0.01 for all treatment groups that are significantly different from each other within the same time point. Also, all treatment groups significantly decreased over time (p<0.001).…”

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-0 by Andreas Peth (85734)

“…Whereas the anti-CSN5 antibody revealed a reduction to 23% as compared to the control, there was no decrease of the CSN complex observed with the anti-CSN8 antibody. …”

Highly Transparent Polyethylcyanoacrylates from Approved Eco-Friendly Fragrance Materials Demonstrating Excellent Fog-Harvesting and Anti-Wear Properties by Muhammad Tamoor Masood (5793218)

“…The same plasticized monomer solutions, dispersing low concentrations of graphene (<0.5 wt %), were allowed to self-assemble on stainless steel surfaces, forming low-friction and anti-wear dry lubricants by decreasing the steel friction coefficient and wear rate by 6- and 10-fold, respectively.…”

Highly Transparent Polyethylcyanoacrylates from Approved Eco-Friendly Fragrance Materials Demonstrating Excellent Fog-Harvesting and Anti-Wear Properties by Muhammad Tamoor Masood (5793218)

“…The same plasticized monomer solutions, dispersing low concentrations of graphene (<0.5 wt %), were allowed to self-assemble on stainless steel surfaces, forming low-friction and anti-wear dry lubricants by decreasing the steel friction coefficient and wear rate by 6- and 10-fold, respectively.…”

Hierarchical cluster analysis of differentially expressed genes in AT-MSCs from three different donors in CC1 or CC2. by Dae Seong Kim (506081)

“…(<b>A</b>) The selected data represented by hierarchical clustering of the normalized Ct of 279 genes on MSCs using individual samples (177 with increased expression, 102 with decreased expression). …”

Dataset: Global oyster reef restoration and recovery by Deevesh Ashley Hemraj (9058922)

“…We found that whilst restoration initiates a rapid increase in biodiversity and abundance of 2- to 5-fold relative to unrestored habitat, recovery rate decreases substantially within a few years post-restoration and accumulated global recovery debt persists at >35% per annum. …”

In the Early Stages of Diabetes, Rat Retinal Mitochondria Undergo Mild Uncoupling due to UCP2 Activity by Ixchel Osorio-Paz (332561)

“…In normal <i>ex vivo</i> retinas, increasing glucose concentrations from 5.6mM to 30mM caused a four-fold increase in glucose accumulation and CO₂ production. …”

Predicted mutation selection windows for <i>E</i>. <i>coli</i> exposed to ampicillin. by Fabrizio Clarelli (3622889)

“…The blue line represents the wild-type strain based on the fits shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008106#pcbi.1008106.g005" target="_blank">Fig 5</a>, and the red line represents a strain with a theoretical resistance mutation that decreases the binding rate (<i>k</i>_f) 100-fold and imparts a 15% fitness cost. …”

CRISPRi knockdown of candidate macrophage pathogenesis genes. by Dustin R. Long (11565529)

“…<p>Fold-difference in measurements of macrophage invasion, normalized to in-batch testing of the parental JE2 strain carrying a GFP-targeted CRISPRi construct(A), and macrophage intracellular survival (B) for specified CRISPRi gene knockdowns. …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Figure bi demonstrates the increase in Rh123 fluorescence at 1 minute, 6 minutes and 12 minutes that reflects mitochondrial membrane depolarisation in PINK1 ko cells. c, d: Single cell traces of PINK1 ko neurons demonstrating that dopamine induced decrease in ΔΨ_m occurs independently of any change in [Ca²⁺]_c in some cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1c</a>), whereas in other cells dopamine induced decrease in ΔΨ_m co-incides with a rise in [Ca²⁺]_c (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1d</a>). e: Incubation with D1/D5 receptor antagonist SCH23390 (20 µM) did not alter the dopamine induced calcium signal or mitochondrial depolarisation in PINK1 ko neurons. f: Dopamine induced mitochondrial depolarisation was prevented by application of the PTP inhibitor 1 µM cyclosporine A.…”

Elimination testing with adapted scoring reduces guessing and anxiety in multiple-choice assessments, but does not increase grade average in comparison with negative marking by Jef Vanderoost (5108072)

“…The comparison is structured around seven hypotheses: in comparison with negative marking, elimination testing with adapted scoring leads to (1) a similar average score (no grade inflation); (2) students expressing their partial knowledge; (3) a decrease in the number of blank answers; (4) no gender bias in the number of blank answers; (5) a reduction in guessing; (6) a decrease in self-reported test anxiety; and finally (7) students preferring elimination testing with adapted scoring over negative marking.…”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…(<b>B</b>) Western Blot analysis of RAS protein expression for the HaCaT cell lines and its derivatives (HaCaTI7, HaCaTII4, A5RT3), shows clear RAS overexpression measured in A5RT3. …”

Behavioral Logic for Operant Training and Discrimination Testing by Samar B Mehta (274037)

“…As this behavior was established, <i>N</i> was increased from 0.063 s to 1.5 s.</p> <p>(C) Stimulus training. All trials in this stage were initiated by a 1.5-s nose poke. …”

Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis and expression of longevity gene Klotho (Microarray dataset) by Sandrine Thuret (10326662)

“…Relatively loose criteria were initially used to filter the data (to minimize analytical false negatives), but genes were required to pass these criteria for each of the four methods to be considered further (four out of four methods) to minimize analytical false positives. </p> <p>A fold change of 1.2 along with a t-test p-value of less than 0.05 was used in RMA and dChip, and a confidence of 50% or higher was used in the Drop Method. …”

Physical activity levels determine exercise-induced changes in brain excitability - Fig 3 by Tea Lulic (3369371)

“…<p>SICI: (A) Group-averaged unconditioned MEPs (i.e. MEP_TS) (with standard errors) for both groups (LOW: N = 13; HIGH: N = 11) at both time points. …”

Prevention of oral cancer by Malki, Ahmed Mohamed

“…Oral cancer is typically discovered late in its development, most often when it has already metastasized to the lymph nodes, at which point prognosis becomes very poor. Therefore, we firmly believe that it is no longer viable that prevention be considered a person’s own responsibility but rather a matter of a group of health professionals. …”
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