TSA and HC-Toxin inhibit Gro dependent repression via the <i>vestigial</i> quadrant enhancer. by Clint J. Winkler (250399)

“…(<b>B</b>) as a function of TSA concentration. Increasing TSA concentration results in a dose dependent decrease in Gro-mediated repression of the <i>vgQ-lacZ</i> transgene. …”

Project Achilles Copy Number Paper by Robin Meyers (2819002)

“…</div><div><br></div><div><br></div><div><br></div><div>Analysis steps v3.3.8a:</div><div><br></div><div>1. QC and identify reps with reproducibility <0.8 or are outliers on PCA or fail FP</div><div>2. remove sgRNAs(guides) with low counts in DNA samples:</div><div>completely remove shRNAs with median <=1 </div><div>3. remove replicates that fail QC measures </div><div>4. fold change(FC) with DNA pool samples </div><div>5. zero-center median of negative controls</div><div>6. collapse replicates per line </div><div>7. sgRNAs are mapped to genes using(Achilles_v3.3.8a.gct)</div><div><br></div><div>Analysis steps v3.3.8:</div><div><br></div><div>1. …”

Model predictions for N vs. P limitation in the youngest Hawai’i and Franz Josef sites. by Duncan N. L. Menge (145217)

“…Input and nutrient use efficiency parameters come from the 300 year old Hawaiian site (<i>I_N</i> = 9.6 kg N ha⁻¹ y⁻¹, <i>I_P</i> = 0.63 kg P ha⁻¹ y⁻¹, <i>ω_N = </i>382 g C g N⁻¹, <i>ω_P</i> = 6780 g C g P⁻¹<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Vitousek5" target="_blank">[37]</a>) and the 5–7 year old New Zealand site (<i>I_N</i> = 1.5 kg N ha⁻¹ y⁻¹<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Menge8" target="_blank">[78]</a>, <i>I_P</i> = 2.2 kg P ha⁻¹ y⁻¹–calculated from the decrease in soil inorganic P from the 5 to the 60 year old site–<i>ω_N = </i>45 g C g N⁻¹, <i>ω_P</i> = 643 g C g P⁻¹<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Richardson1" target="_blank">[5]</a>), with the other parameters as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone-0042045-g005" target="_blank">Fig. 5a</a>.…”

Effect of Mediator disruption on euchromatic genes. by Eriko Oya (446107)

“…<p>Venn diagram showing the number of transcripts whose expression levels are increased (up) or decreased (down) >1.5-fold in mutants compared to the wild-type. …”

Performance of RFECS for enhancer predictions in H1 and IMR90 cells. by Nisha Rajagopal (389555)

“…<p>Area under the 5-fold cross-validated ROC curve decreases with increase in number of trees stabilizing gradually in A.)H1 and B.)IMR90 cells. …”

Spf1 affects the cellular distribution of Mn²⁺. by Yifat Cohen (504564)

“…By looking at the fold change of ion concentration of Δ<i>spf1</i> or OE-Spf1 microsomes relative to WT it can be seen that Mn²⁺ is the only ion that decreases in Δ<i>spf1</i> and increases in microsomes of OE-Spf1. …”

Sensitivity analysis of the model parameters. by Roswitha Dolcemascolo (12511789)

“…<p>Plots of mean and noise of expression as a function of IPTG, where solid lines correspond to the dynamics predicted with the adjusted parameter, dotted lines to the dynamics if the parameter increases 2-fold, and dashed lines to the dynamics if the parameter decreases 2-fold.…”

GOAT MILK MANGO YOGHURTS: PHYSICOCHEMICAL STABILITY DURING OR STORAGE by Yvana Maria Gomes dos Santos (5959919)

“…The aim of this study is to assess the stability of the procedure in the production of processed yogurt with goat milk and sleeve pulp. Five different yogurt formulations were processed using varying concentrations of sucrose (5, 10 and 15%) and mango pulp (4, 5 and 6%). …”

Prevalence of self-referred chronic pain and intercurrences in the health of the elderly by Ezequiel Vitório Lini (5255471)

“…CONCLUSION: Measures to decrease chronic pain in the elderly should be priority, especially in primary health attention services, because this is a multidimensional and complex public health problem.…”

Paradigm and results of Experiment 2: Unambiguous pre-exposure. by Maartje Cathelijne de Jong (334147)

“…<p><b>A</b>) The paradigm. The pre-exposure period had a fixed duration (4.3 minutes) and contained either an ambiguous globe, a globe disambiguated using binocular depth-cues (disparity) or a globe disambiguated using monocular depth-cues (contrast- and size-imbalance). …”

Comparison between selecting mt protein-coding (PC) genes by individual gene performance vs. by length. by Justin C. Havird (507301)

“…<p>Utilizing the three mt protein-coding (PC) genes that individually performed “best” (based on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084080#pone-0084080-g003" target="_blank">Figure 3:</a> ND5, ND4, ND2), rather than the three longest (i.e, ND5, COX1, and ND4) mt PC genes, resulted in a significantly lower decrease in Ln <i>L</i> (± S.E.M.) compared to the “supergene” (i.e., all 13 mt PC genes) topology (<i>t</i>-test, <i>t</i> = 2.21, <i>df</i> = 1, 66, <i>P</i> = 0.03). …”

Characterization of urinary exosomes. by Tim Lange (2385133)

“…Zetasizer analysis of urinary exosome samples (C). The results of the 5 measurements of the urine sample displayed in TEM (A) are shown (C, a). …”

Endocytosed albumin co-localized with lysosomes and was degraded in podocytes. by John M. Carson (577297)

“…<p>Confocal microscopy image demonstrating co-localization of albumin and lysosomes in a podocyte treated with 1.5 mg/mL FITC-albumin and Cathepsin B Magic Red for 1 hour. …”

Activated carbon loaded with manganese and iron for glyphosate adsorption: Kinetics, isotherms and thermodynamic studies by Natalia Ueda Yamaguchi (6722057)

“…Adsorption isotherm experiments were carried out at 5, 15, 25, 35 and 45°C. The adsorption isotherms presented a better fitting using the Freundlich model (R2>0.98), indicating a multilayer adsorption of glyphosate. …”

Kinetics of PfR6 interaction with HMG-box. by Diego F. Joseph (6569912)

“…Mixing the labeled protein with the probe-bound aptamer (green) resulted in a decrease of fluorescence over time, indicating that the binding of both components results in the quenching of fluorescein due to its vicinity with the quencher in the protein. …”

The Effect of p38MAPK on Cyclic Stretch in Human Facial Hypertrophic Scar Fibroblast Differentiation by Qi-cui Du (468638)

“…The fibroblasts were synchronized and randomly assigned to two groups: cyclic stretch and cyclic stretch pre-treated with SB203580 (a p38MAPK inhibitor). Cyclic stretch at 10% strain was applied at a loading frequency of 10 cycles per minute (i.e. 5 seconds of tension and 5 seconds of relaxation) for 0 h, 6 h and 12 h. …”

Homozygous <i>mray</i> mutants show severe craniofacial malformations starting early in development. by Adam P. Ross (437534)

“…<p><b>A, B,</b> Fluorescent images of a wild-type embryo compared to a homozygous <i>mray</i> littermate at E12.5. …”

Data_Sheet_1_Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis.PDF by Maja Kesić (8620716)

“…<p>Central and peripheral pools of biogenic monoamine serotonin (5-hydroxytryptamine [5HT]) exert opposite effects on the body weight regulation: increase in brain 5HT activity is expected to decrease body weight, whereas increase in peripheral 5HT activity will increase body weight and adiposity. …”

Hh ligands produced by tumor cells impacts the osteoblast differentiation and expression of RANKL and PTHrP. by Shamik Das (174657)

“…Addition of the Hh neutralizing antibody, 5E1, caused a reduction in ALP activity. SUM1315+5E1 (∧p = 0.014); MDA-MB-231+5E1 (p = 0.12), SUM159+5E1 (∧p = 0.04), MDA-MB-435+5E1 (p = 0.6). …”

Contrasting transcriptomes of somatic, OSKM transduced HFF1 and pluripotent cell types. by Nancy Mah (105583)

“…The normalized expression values (z-score) of 6179 transcripts (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024351#pone.0024351.s007" target="_blank">Data S1</a>) regulated at any timepoint or in iPS/ES cells with respect to HFF1 cells (p_adj<0.05; fold change >1.5) are shown. …”