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78701
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78702
Hexokinase 2 (Hxk2) is the main 2DG-phosphorylating enzyme <i>in vivo</i>.
Published 2022“…Values are normalized to the value of the WT / 15 min (n = 3 independent experiments ± SEM, <i>p</i>value indicated, paired <i>t</i>-test) (<b>B</b>) 2DG causes a decrease in ATP content as visualized using a FRET ATP biosensor. …”
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78703
Properties of <i>Drosophila</i> circadian promoters.
Published 2016“…From top to bottom, left to right: p = 0.0023, p = 0.16, p = 0.29, p = 0.066, rank sum tests. The last p value (mean for CLK vs. no CLK) became much smaller when considering all expressed transcripts: p = 2.5×10<sup>−17</sup>, median ratio 1.4 CLK vs. no CLK (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006231#pgen.1006231.s008" target="_blank">S3 Table</a>). …”
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78704
Over-expression of Fas2 in the wing imaginal disc causes an EGFR-dependent reduction in organ size.
Published 2024“…At right, a clone in the Posterior compartment between vein V and the posterior wing margin (green arrow) causes an abnormal shape due to the reduction in size of the posterior region of the wing, while another clone between veins II and III causes a size decrease in the anterior compartment (green arrow). …”
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78705
Additional file 2 of Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway
Published 2025“…Statistical analysis revealed no significant differences in CD80+ expression between MCAO and Evobrutinib group while the expression of MHCII+ microglia decreased in Evobrutinib group compared to MCAO. Mean±SEM, n=5, one-way ANOVA, vs sham: * P < 0.05; MCAO vs Evobrutinib, ### P< 0.001,ns: no significance.…”
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78706
ATTRIBUTES AND CHANCES OF ELECTORAL SUCCESS OF MAYORS IN BRAZIL
Published 2019“…The results show evidence that the candidate’s sex and occupation are decisive influencing factors, with a decrease in chances of electoral success for male candidates or candidates of a political career in the elections of 2012 and 2016.…”
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78707
Facilitating Tumor Functional Assessment by Spatially Relating 3D Tumor Histology and <em>In Vivo</em> MRI: Image Registration Approach
Published 2011“…The registration accuracy was assessed by root mean squared (RMS) distances between manually annotated landmark points in both modalities. …”
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78708
Flexibility of the framework in adapting different time-scales.
Published 2025“…</p> <p>Here, and therefore, in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013642#pcbi.1013642.s012" target="_blank">S12b Fig</a>, when population spends half of the day in their home regions, infections increase in region 2 and decrease in region 1 and region 3 in comparison to <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013642#pcbi.1013642.s012" target="_blank">S12a Fig</a>.…”
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78709
Data Sheet 1_Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis.pdf
Published 2025“…Notably, an increase in T-lymphocyte numbers is observed in neonates and infants (0 – 1 year of age) towards less differentiated T-lymphocyte subpopulations, while an increase into more differentiated subpopulations emerges later (1 – 5 years of age).</p>Conclusion<p>A comprehensive systematic review and meta-analysis of T-lymphocyte age-dependent homeostasis in healthy humans was performed, to evaluate immune T-cell profiles as a function of age and to characterize generalized estimates of T-lymphocyte counts across age groups. …”
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78710
DataSheet_1_Integrated physicochemical, hormonal, and transcriptomic analysis reveals the underlying mechanism of callus formation in Pinellia ternata hydroponic cuttings.pdf
Published 2023“…P. ternata is used as the source material and is grown in a hydroponic system, increasing the seedling production rate 10-fold compared with the traditional cultivation mode. …”
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78711
Foxj1 controls the expression of OSN-specific genes, but not ciliary motility genes.
Published 2024“…MCCs are depleted in <i>foxj1a/b</i> double mutants, and, therefore, expression of these genes were absent in the nasal placodes (bottom panel) (<i>n</i> = 5 for <i>dnah5</i>, <i>n</i> = 6 for <i>dnah8</i>, <i>n</i> = 4 for <i>dnah9</i>). …”
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78712
Hypothalamic Sirt1 regulates food intake through melanocortin receptors
Published 2009“…<p>. <i>(A)</i> Pharmacological inhibition of Sirt1 decreases food intake (left) and body weight gain (middle) in fasted rats, whereas activation of Sirt1 increases food intake (right) in re-fed rats. n = 8–9, per treatment, and per group. …”
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78713
Detection task performance of the bimodal experiment.
Published 2015“…Δ<sub>84</sub> displays the relative amount of threshold shift of the bimodal compared to the unimodal psychometric function at a performance of 84%. A positive shift indicates a threshold decrease. …”
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78714
Exogenous expression of variants of the small G protein, N-Ras, inhibits HIV-1 gene expression.
Published 2020“…(<b>B</b>) Representative gel of Gag-GFP expression detected by GFP fluorescence from reducing SDS-PAGE and representative immunoblots of ERK1/2 (phospho and total), HA-tagged N-Ras, and α-tubulin/GAPDH assayed from 30 μg of cell lysates (representative of n ≥ 3–5). (<b>C-D</b>) Graphs quantifying the level of expression of (<b>C</b>) HIV-1 Gag described in (<b>B</b>, n ≥ 3–5, mean, s.e.m.) and (<b>D</b>) HIV-1 RNAs detected by qRT-PCR as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008307#ppat.1008307.g002" target="_blank">Fig 2A and 2B</a> (n ≥ 3, mean, s.e.m.). …”
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78715
Src activation is abrogated in the presence of β1 blocking mab.
Published 2016“…<p>(A) Cultured mouse podocyte lysates show decrease in Src Y416 phosphorylation in the presence of β1 blocking mab suggesting decreased activation of Src kinases when integrin β1 activation is prevented. …”
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78716
<i>skn-1</i> expression is most critical from the late larval development through day 1 of adulthood to counter polyglutamine (polyQ) induced proteotoxicity.
Published 2021“…<p>(<b>A</b>) The knockdown of <i>skn-1</i> by RNAi significantly decreased the thrashing rates of worms that express polyQ35-YFP in their muscles (strain AM140) at day 2, 4 and 6 of adulthood (reduction of 11.64%, 12.29% and 27.60%, respectively). 80 worms were scored per treatment per timepoint. …”
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78717
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78718
Lung bacterial burden as measured by colony forming units (CFU) over time.
Published 2015“…At all time points measured, no significant statistical differences were noted between the TV Ad35+ group, the vector control group, NC-V, and the main control group, NC-T4 (ANOVA) Boosting with Ad26-TBS at week 16 did not result in decreased bacterial burden by week 28 compared to all other groups in the study (p = 0.14, ANOVA)</p>…”
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78719
The comparison of IGSA clustering with different similarity measurement.
Published 2016“…The survival time in both methods (A, B) tended to decrease. However, the red curve in B was too smooth to divide the samples into different disease classes.…”
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78720
The LPal inputs to RS neurons are also relayed in the MLR.
Published 2018“…Middle: RS neuron responses to the electrical stimulation (15–20 μA) of the LPal. A local injection of the glutamate receptor antagonists AP5/CNQX in the MLR (see schematized brain, upper panel) strongly decreased the RS neuron responses. …”