Cut-off performance dependence of Sting-LDA-WNA classifier. by Fábio R. de Moraes (516010)

“…When the cut-off is increased from 0.10 to 0.50, the accuracy increases and reaches its peak, and then it gradually decreases with a further increase in the cut-off value. …”

Risk Factors and Outcomes for Late Presentation for HIV-Positive Persons in Europe: Results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHER... by Amanda Mocroft (288350)

“…In the first year after HIV diagnosis, LP was associated with over a 13-fold increased incidence of AIDS/death in Southern Europe (adjusted incidence rate ratio [aIRR] 13.02; 95% CI 8.19–20.70) and over a 6-fold increased rate in Eastern Europe (aIRR 6.64; 95% CI 3.55–12.43).…”

Figure 4 by Timothy Pearson (569777)

“…<p>(A) DHE loaded single muscle fiber, (i) Fluorescent image obtained using excitation at 405 nm, (ii) Fluorescent image obtained using excitation at 488 nm, (iii) Fluorescent image obtained with 405 nm emission and 450/35 nm emission monitoring non-oxidised DHE, (iv) bright field image, scale bar = 50 µm, (v) merged figures i–iii. …”

Evoked neural activity in the SEG of control and stung cockroaches. by Ram Gal (365768)

“…Peri-stimulus time histograms for wind (left) and tactile (right) stimuli. Each data point represents the mean (± SEM) number of spikes within a 20 ms time bin. …”

PRDM9 binds in vitro to meiotic recombination hotspots. by Corinne Grey (200646)

“…The likely PRDM9^wm7 binding sequences in the B10 and CAST strains are shown, with SNPs underlined (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001176#pbio.1001176.s005" target="_blank">Figure S5</a> for in silico prediction). …”

JNK3-N-Tat attenuated the MPP^+/MPTP-induced activation of JNK3 by inhibiting the binding of β-arrestin2 to JNK3 following MPP⁺-induced injury. by Jing Pan (95938)

“…<p>SH-SY5Y cells were pretreated with vehicle, JNK3-N-Tat, or JNK3-4A-Tat 1 h before MPP⁺ (3 mM) treatment and then cultured for 12 hr before analysis. …”

DataSheet_1_Polymeric nanocapsules loaded with poly(I:C) and resiquimod to reprogram tumor-associated macrophages for the treatment of solid tumors.pdf by Clément Anfray (9090641)

“…</p>Results<p>We have developed polymeric NCs loaded with poly(I:C)+R848. Among a series of 5 lead prototypes, protamine-NCs were selected based on their physicochemical properties (size, charge, stability) and in vitro characterization, showing good biocompatibility on primary macrophages and ability to stimulate their production of T-cell attracting chemokines (CXCL10, CCL5) and to induce M1-like macrophages cytotoxicity towards tumor cells. …”

Supplementary Material for: Diagnosis of Severe Fetomaternal Hemorrhage with Fetal Cerebral Doppler: Case Series and Systematic Review by Bellussi F. (3917861)

“…Patients were seen at 31 ± 5 weeks' gestation (range 16-39) and the most frequent indication for referral was decreased perception of fetal movements. …”

BMD-mediated restoration of Tfam protein expression in ischemic retina. by Dongwook Lee (303539)

“…<p>BMD or vehicle were injected once by IP at 24 hours before and at the time of initial IOP elevation for 24 hours after ischemia. (A) BMD significantly decreased Tfam protein expression compared with vehicle-treated ischemic retina. …”

Image_2_T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.tif by Winnie G. Vos (15415025)

“…Mice lacking T cell CBL-B had a 1.4-fold increase in CD8⁺ T cells and a 1.8-fold increase in regulatory T cells in the spleen. …”

Image_3_T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.tif by Winnie G. Vos (15415025)

“…Mice lacking T cell CBL-B had a 1.4-fold increase in CD8⁺ T cells and a 1.8-fold increase in regulatory T cells in the spleen. …”

Image_4_T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.tif by Winnie G. Vos (15415025)

“…Mice lacking T cell CBL-B had a 1.4-fold increase in CD8⁺ T cells and a 1.8-fold increase in regulatory T cells in the spleen. …”

Image_1_T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.tif by Winnie G. Vos (15415025)

“…Mice lacking T cell CBL-B had a 1.4-fold increase in CD8⁺ T cells and a 1.8-fold increase in regulatory T cells in the spleen. …”

Inhibitory effect of pirfenidone on TGF-β2-induced migration of SRA01/04 cells. by Yangfan Yang (380720)

“…<p>Light microscope images show decreased migratory ability of cells at 24 hours, after scratches were applied to the cells with 0, 0.25, or 0.5 mg/mL pirfenidone in the absence or presence of TGF-β2. …”

Prb1 overexpression promoted APC entry into vacuoles in <i>vps21Δ</i> cells (but not in <i>ypt1ts</i> and <i>ypt7Δ</i> cells) after nitrogen starvation. by Zulin Wu (4451572)

“…<p><b>A.</b> The accumulation of GFP-Atg8-labeled APCs in <i>vps21Δ</i> cells decreased after Prb1 overexpression. …”

Influence of miR-214 on cell migration and invasion in SGC7901 and MKN28 cells. by Ya-Wen Wang (533084)

“…<p>(A, C) Representative pictures of migration and invasion assays in SGC7901 and MKN28 cells (magnification 200×) are shown. …”

DeepTrajectory method overview. by Erik Pfeiffenberger (5714645)

“…<p>The method predicts improved conformational states, that more closely resemble the crystal structure observed conformation, in molecular dynamics (MD) trajectory data of template based models. (A) During sampling of the initially folded proteins with different MD based sampling protocols, transitions to conformations can be observed that represent an improved conformational state (ΔGDTTS ≥ 0.01), decreased conformational state (ΔGDTTS ≤ −0.01) and no-change in conformational state (|ΔGDTTS| < 0.01). …”

Use-dependency of SPX on <i>I</i>_CaL. by Jae Gon Kim (2549308)

“…<p>A, Repetitive application of depolarizing pulses (shape is shown in the figure inset) to 0 mV from a holding potential of −50 mV gradually decreased the <i>I</i>_CaL amplitude. …”

Final Supplemental figures from β-Cryptoxanthin Reduced Lung Tumor Multiplicity and Inhibited Lung Cancer Cell Motility by Downregulating Nicotinic Acetylcholine Receptor α7 Signal... by Anita R. Iskandar (2626633)

“…The columns represent the mean {plus minus} sem. * P = 0.04. Dotted lines indicated significant decreasing levels in a BCX-dose dependent manner (P-linear trend = 0.05). …”

Cordycepin-resistance strains are not cross resistant to suramin, pentamidine and melarsoprol. by Suman K. Vodnala (261272)

“…The fraction of parasites in comparison to untreated controls is depicted. A, F Four months after incubation with cordycepin, parasites reached a 40–60 fold decreased sensitivity to cordycepin. …”