Als acts downstream of GSK3β and upstream of SCF/Slimb/βTRCP E3 Ub ligase. by Gerlinde Reim (654594)

“…Combined <i>als</i> and <i>ter94</i> depletion caused an elevation of <i>wf</i> (lane 2) or a decrease of <i>arr</i> (lane 5). No alteration was observed for the Hh target gene <i>ptc</i> (lanes 7–9). …”

Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break Repair by Daniel Lucas (13351)

“…In Polμ^−/− mice, hematopoietic development was defective in several peripheral and bone marrow (BM) cell populations, with about a 40% decrease in BM cell number that affected several hematopoietic lineages. …”

Epithelial cell derived TGF-β mediates anti-inflammatory effects on MDMs. by Ameya Sathe (506310)

“…Treatment with recombinant TGF-β decreased secretion of TNF-α from MDMs in a dose dependent manner. …”

Time course of activity levels in middle-aged female mice. by David R. Bonsall (813770)

“…(B) Similar reductions in wheel-running activity were seen in mice given 50ng IL-1β i.c.v. (n = 5). (C) The total number of wheel-running sessions during the dark period was reduced by IL-1β, with increased fatigability (measured as decreased bout duration) (D) seen during each session as compared to baseline levels. …”

Inhibition of CFTR activity by fractions from Chinese wild grapevine. by Yaofang Zhang (112836)

“…<p>A. A representative plate with positive fractions in screening by cell-based fluorescent assay. …”

Kank/EB1 binding is via an EB1 binding, SxIP, motif in the middle region of Kank. by Sara M. R. Clohisey (627652)

“…<p>(A) A summary of Kank truncations and their microtubule plus end localisation. ++ (strong localisation), + (weak localisation), - (no localisation). …”

Serial coalescence of microbial communities. by Pablo Lechón-Alonso (11663433)

“…The standard deviation is decreasing along the x axis and is never more than 40% of the mean for all the curves (not shown to reduce clutter). …”

Perfusion of substance P (8 μM) had no effect on the amplitude of PS1 but reduced paired pulse depression by Kerrie N Wease (12951)

“…(c) Pooled time course data from the same set of experiments showing PS2 expressed as a % of PS1. Substance P (8 μM) perfused for 10 min (black bar) significantly increased PS2 amplitude and therefore decreased paired pulse depression. …”

Illustration of the time course of the protocol by Qin Lu (995)

“…The lower panel represents the time course of the protocol for 7 patients for whom a CT scan and P–V curve in ZEEP were acquired after 15 minutes of mechanical ventilation without PEEP. …”

Summary of cytokines array gene expression changes in striatum due to RGFP966 treatment. by Haiqun Jia (748180)

“…Dotted lines on x-axis denote a fold-change cut-off of > +/- 2.</p>…”

Computational analysis of cell contact area in IRM images. by Daniel J. Modulevsky (307313)

Data_Sheet_1_Strongly Bent Double-Stranded DNA: Reconciling Theory and Experiment.pdf by Aleksander V. Drozdetski (8058689)

“…As the bending deformation increases beyond a certain (polymer-specific) point, the change in the convexity properties of the effective bending energy of the polymer makes the harmonic deformation energetically unfavorable: in this strong bending regime the energy of the polymer varies linearly with the average bending angle as the system follows the convex hull of the deformation energy function. …”

Effect of the seal resistance on circuit parameters. by Matej Hoťka (4610938)

“…<p><b>A:</b> The simulated data. <i>Left panel</i>: Dependence of estimates of cell impedance parameters on <i>R</i>_<i>Seal</i> value (estimated by Eqs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188452#pone.0188452.e001" target="_blank">1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188452#pone.0188452.e014" target="_blank">8</a> from simulated current responses of the equivalent circuit according <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188452#pone.0188452.e010" target="_blank">Eq 5</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188452#pone.0188452.g001" target="_blank">Fig 1A</a>, <i>C</i>_<i>M</i> = 140 fF, <i>R</i>_<i>M</i> = 0.5 GΩ, <i>R</i>_<i>A</i> = 4 MΩ). …”

CTV data with AS-3 buffer pH gradient. by Mitchell R. H. Weigand (11383844)

“…<p>A sample from donor F1 was measured using AS-3 as the RBC storage solution at five different pH values. …”

9.2.27PE in combination with ABT-737 causes synergistic cell cytotoxicity in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) The 9.2.27PE immunotoxin caused a time- and dose dependent decrease of cell viability in melanoma cells. …”

DNA methylation levels in different groups. by Fan Gao (130617)

“…<p>Analysis of sample DNA methylation mean β values for all probes, TSS200 probes, TSS1500 probes, 1^st Exon probes, Gene Body probes, 3′UTR probes, and 5′UTR probes. …”

SEAwise Report on improved predictive models of growth, production and stock quality. by Leire Ibaibarriaga (13760979)

“…In contrast, the results of the body condition indices showed a moderate but significant decrease for all the studied 19 species over time. …”

Data_Sheet_1_Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii.docx by Mei-Ling Han (1612951)

“…Cell wall biosynthesis was inhibited at 4 and 24 h by aztreonam alone and the combination as shown by the decreased levels of two amino sugars, UDP-N-acetylglucosamine and UDP-N-acetylmuramate; these results suggested that aztreonam was primarily responsible for the synergistic killing at later time points. …”

Data_Sheet_2_Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii.xlsx by Mei-Ling Han (1612951)

“…Cell wall biosynthesis was inhibited at 4 and 24 h by aztreonam alone and the combination as shown by the decreased levels of two amino sugars, UDP-N-acetylglucosamine and UDP-N-acetylmuramate; these results suggested that aztreonam was primarily responsible for the synergistic killing at later time points. …”

Data_Sheet_3_Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii.xlsx by Mei-Ling Han (1612951)

“…Cell wall biosynthesis was inhibited at 4 and 24 h by aztreonam alone and the combination as shown by the decreased levels of two amino sugars, UDP-N-acetylglucosamine and UDP-N-acetylmuramate; these results suggested that aztreonam was primarily responsible for the synergistic killing at later time points. …”