Pleiotropin enhances the osteo/dentinogenic differentiation potential of dental pulp stem cells by Luyuan Jin (8961071)

“…<p><b>Purpose:</b> Pleiotrophin (PTN) is a heparin-binding growth-associated molecule and expressed in ameloblasts and odontoblasts throughout tooth maturation. …”

Table_4_Omics-Based Mechanistic Insight Into the Role of Bioengineered Nanoparticles for Biotic Stress Amelioration by Modulating Plant Metabolic Pathways.DOCX by Madhuree Kumari (3699274)

“…The particles reduced disease severity by 70–80% at 5 μg/ml without showing phytotoxicity. It elicited plant immunity by a significant reduction in reactive oxygen species (ROS), decreases in stress enzymes by 0.6–19.8-fold, and emergence of autophagy. …”

Table_1_Omics-Based Mechanistic Insight Into the Role of Bioengineered Nanoparticles for Biotic Stress Amelioration by Modulating Plant Metabolic Pathways.DOCX by Madhuree Kumari (3699274)

“…The particles reduced disease severity by 70–80% at 5 μg/ml without showing phytotoxicity. It elicited plant immunity by a significant reduction in reactive oxygen species (ROS), decreases in stress enzymes by 0.6–19.8-fold, and emergence of autophagy. …”

Data_Sheet_1_Differential Genome Size and Repetitive DNA Evolution in Diploid Species of Melampodium sect. Melampodium (Asteraceae).PDF by Jamie McCann (3111606)

“…Melampodium, representing all but two of its diploid taxa, in a phylogenetic context. The investigated genomes range in size from 0.49 to 2.27 pg/1C (ca. 4.5-fold variation), despite having the same base chromosome number (x = 10) and very strong phylogenetic affinities. …”

Data_Sheet_1_Omics-Based Mechanistic Insight Into the Role of Bioengineered Nanoparticles for Biotic Stress Amelioration by Modulating Plant Metabolic Pathways.pdf by Madhuree Kumari (3699274)

“…The particles reduced disease severity by 70–80% at 5 μg/ml without showing phytotoxicity. It elicited plant immunity by a significant reduction in reactive oxygen species (ROS), decreases in stress enzymes by 0.6–19.8-fold, and emergence of autophagy. …”

Fis1ΔTM membrane binding requires negatively charged lipids. by Robert C. Wells (348960)

“…<p>A vesicle sedimentation assay was used to measure fraction of Fis1ΔTM bound to lipid vesicles as a function of decreasing concentration of anionic DOPG at pH 5.0(A) or pH 7.0(B). …”

Thirty-year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes by Michael Fang (9708234)

“…</p> <p><b>Results: </b>From 1988-1994 to 2011-2018, there was a significant decrease in the prevalence of albuminuria (38.9 to 18.7%, p-for-trend<0.001), but no change in the prevalence of reduced eGFR (7.5 to 9.9%, p-for-trend=0.30), retinopathy (1988-1994 to 1999-2008 only; 13.2 to 12.1%, p-for-trend=0.86), or self-reported cardiovascular disease (19.0 to 16.5%, p-for-trend=0.64). …”

Expression of Sox2, Sox10, Gata3, Prox1 and Peripherin during primary auditory neuron development and maturation. by Koji Nishimura (2077804)

“…At E10.5, Sox10 was downregulated as neuroblasts delaminated from the otocyst. …”

Evaluation of emerging NASH therapies: the impact of treatment efficacy profiles on long-term health outcomes: Supplementary materials by William L Herring (14039541)

“…The fibrosis worsening profile reduced predicted 10-year LRC rates (F1:</p> <p>1.9%; F2: 6.5%; F3: 19.1%; F4/CC: 55.0%) more than the resolution and fibrosis improvement profiles</p> <p>(F1: 2.6%/2.6%; F2: 8.5%/8.3%; F3: 23.3%/23.0%; F4/CC: NA/59.0%). …”

Secondary metabolites from <i>Gentiana cruciata</i> L. and their anti-inflammatory and analgesic activities by Rima Konya (14075753)

“…<p>A previously unreported secoiridoid glycoside, cruciatoside (<b>1</b>) was isolated from the aerial parts of <i>Gentiana cruciata</i> L. along with ten known compounds eustomoside (<b>2</b>), eustomorusside (<b>3</b>), gentiopicroside (<b>4</b>), 6'-<i>O</i>-β-D-glucopyranosyl gentiopicroside (<b>5</b>), loganic acid (<b>6</b>), isoorientin (<b>7</b>), isovitexin (<b>8</b>), isovitexin 2''<i>-(E)-</i>ferulate (<b>9</b>), mangiferin (<b>10</b>), and 2-methyl-inositol (<b>11</b>). …”

MPs^PPARα+/+-induced EPC differentiation and <i>in vitro</i> angiogenesis of mature ECs involve NF-κB pathway activation. by Tarek Benameur (196206)

“…<p>(<b>A</b>) Western blot showing that MPs^PPARα+/+ induced I-κB phosphorylation on activator sites (Ser32/36) in EPCs, indicating that NF-κB pathway is activated. …”

DNMT1-mediated demethylation of lncRNA MEG3 promoter suppressed breast cancer progression by repressing Notch1 signaling pathway by Tingting Pan (4735617)

“…Functionally, treatment of breast cancer cells with the DNA methylation inhibitor 5-AzadC as well as silencing of DNA methyltransferase-1 (DNMT1) could decrease the abnormal hypermethylation of the MEG3 promoter, reverse MEG3 expression, inhibit cell proliferation and promote cell apoptosis. …”

Identification of Differentially-Expressed Genes Associated with Pistil Abortion in Japanese Apricot by Genome-Wide Transcriptional Analysis by Ting Shi (3955)

“…<div><p>The phenomenon of pistil abortion widely occurs in Japanese apricot, and imperfect flowers with pistil abortion seriously decrease the yield in production. Although transcriptome analyses have been extensively studied in the past, a systematic study of differential gene expression has not been performed in Japanese apricot. …”

Evolutionary dynamics of iPD-population consisting of two types of players: With WSLS and AllD strategies. by Anton M. Unakafov (5706560)

“…<p>(A) Initially, both types have the same frequency, but after 40 generations the fraction of WSLS-players <i>x</i>₁(<i>t</i>) converges to 0 for probabilities to see partner’s choice <i>p</i>_see = 0.0, 0.2 and to 1 for <i>p</i>_see = 0.4, 0.5. …”

Effect of Vitrification on the MicroRNA Transcriptome in Mouse Blastocysts by Xueming Zhao (400630)

“…Of these, the expression levels of five miRNAs differed significantly: in the vitrified blastocysts, four miRNAs (mmu-miR-199a-5p, mmu-miR-329-3p, mmu-miR-136-5p and mmu-miR-16-1-3p) were upregulated, and one (mmu-miR-212-3p) was downregulated. …”

FDG PET parameters and survival curves. by Julien Ganem (7490378)

“…<p>Survival curves using the Kaplan-Meier method. <b>(a)</b> PFS was longer for patients with low TLG₂ (HR = 2.8, 95%CI 1.3–5.9, p< 0.01). …”

Loss of FHL2 reduces intestinal polyp multiplicity. by Charlotte Labalette (365229)

“…<p>(A) Representative images of intestines from 11-month-old <i>Apc^Δ14/+FHL2^+/+</i> and <i>Apc^Δ14/+FHL2^−/−</i> mouse. …”

Comparison of two physiotherapy treatments in reducing pain and increasing functional autonomy of elderly patients with gonarthrosis by Stela Freitas Raymundo (12817830)

“…Similarly, there was significant decrease (p<0.001) in the level of pain in both EG1 (Δ=5.09) and EG2 (Δ=7.1). …”

Image_2_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF by Dov Borovsky (8892182)

“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”

Image_1_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF by Dov Borovsky (8892182)

“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”