Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL by Michael J. Ricciardi (4102375)

“…We collected blood from a female with a maculopapular rash at day (D) 5 and D7 post onset of symptoms (POS) and we continued weekly blood draws out to D148 POS. …”

Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways by Zhao Zeng (478844)

“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”

A Multi-echelon Network Distribution Model For Emergency Resource Planning by Pradhananga, Rojee

“…The structure at its highest echelon consists of a set of potential Supply Points (SPs), where resources are purchased and consolidated which is more practical in comparison to the conventional centralized structure. …”
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Clinical molecular testing for <i>ASXL1</i> c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era - Fig 2 by Santiago Montes-Moreno (135753)

“…As shown in the figure, there is a shift in the clonal composition of the disease with a decrease in the three <i>IDH1</i> mutations first identified (<i>IDH1</i> c603_606del p.S202fs*7, <i>IDH1</i> c624T>G p.Y208* and <i>IDH1</i> c611G>A p.G204D) after therapy, but the emergence of new clones characterized by <i>FLT3</i> c.1471G>C p.V491L, <i>NPM1</i> c393_395dupGGA p. …”

Conditional <i>Cdk5rap2</i> KO mouse and novel <i>mCdk5rap2</i> splice variants. by Nadine Kraemer (790327)

“…(D) Identification of a novel <i>mCdk5rap2</i> splice variant (<i>mCdk5rap2-V1</i>) through gel electrophoresis and sequencing of PCR products from exon 2 to exon 7 of WT and hom KO cDNA. …”

Effects of the unilateral submaximal eccentric exercise on knee flexor’s of neuromuscular function and perceived muscle soreness (PMS) of both the EL (exercised limb) and the NEL (... by Jennifer Gioda (17951785)

Genetic analysis of <i>OBSCN</i> c.13330 C>T and <i>FLNC</i> c.5161delG mutations. by Daniela Rossi (1716643)

Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting by Sara Gallo (3111309)

“…This resulted in STAT5 down-regulation and a decrease in miR-21 content, TGFβ expression and matrix protein synthesis within MCs. …”

Interactomes of HMR/LHR interactors provide evidence for the existence of a defined HMR protein complex (related to Fig 1). by Andrea Lukacs (3752956)

Synonymous Rare Arginine Codons and tRNA Abundance Affect Protein Production and Quality of TEV Protease Variant by Jie Fang (306330)

“…<div><p>It has been identified that a TEV protease (TEVp) variant, TEVp^5M, displays improved solubility. …”

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Changes after 45 minutes in the proportion of LTP, LTD or no plasticity responses observed in L5PyNs population induced by the HFS protocol in the presence of D1R agonist or antago... by Claire Nicole Jeanne Meunier (703124)

“…<p>(A and D) Percentages of L5PyNs displaying LTP, LTD or no plasticity in 129/Sv mice and 5-HT_1AR-KO mice in control conditions. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Our results reveal significant variations in the behavior of the immune complex structure across five different membrane compositions, which include POPC, POPA, DPPC, and DLPC phospholipids, and a mixed POPC/cholesterol system. …”

BrdU assay in control siRNA (blue bars) and in PAX6 knockdown (red bars) limbal epithelial cells (LECs) without and after 1µM or 5µM RA incubation for 48 hours. by Shao-Lun Hsu (6856259)

“…Significant p values (<0.05) are highlighted. BrdU assay shows a significantly lower proliferation rate in the PAX6 siRNA knockdown group than in control siRNA group (p < 0.001). 5µM RA treatment significantly decreased proliferation rate in controls (p = 0.025). …”

Table_5_Bacillus velezensis B105-8, a potential and efficient biocontrol agent in control of maize stalk rot caused by Fusarium graminearum.DOCX by Shuang Wang (46453)

“…S-NP activity showed an initial increase with a peak of 20,337 nmol/h/g, followed by a decrease, but activity remained significantly better than control treatment with chemical fungicides. …”

Boxplot of children’s rated emotion valence during the baseline phase, and on the first and second test trial of Study 1. by Stella C. Gerdemann (12436680)

Evolution of the fraction of global infection with a non-linear trade-off. by Koich Saeki (4797375)

“…<p>(a) A linear trade-off between the degree of global infection <i>G</i> (horizontal axis) and that of local infection <i>L</i> (vertical axis) assumed so far (dashed curve), and a non-linear trade-off examined here (solid curve), where the local infection decreases in proportional to . …”

FIG1A- FIG1N. by Elaine Carvalho de Oliveira (11630455)

Comparing Cosine and Sine Functions for Calculating the Magnetic Shielding of ²⁹Si Nuclei across Siliceous Zeolites by A. A. Rybakov (4812234)

“…The models, along with α-quartz, were considered to evaluate the advantages of the effects on both chemical shifts and chemical shift anisotropies, as measured for α-quartz and ZSM-12. The decrease of the O dipole with the Si–O–Si angle is usually interpreted as a variation of the electronic density at the O lone pairs. …”

Organelle recombination genes and body plans across taxa. by David M. Edwards (10692265)