Image1_Human induced pluripotent stem cells (hiPSCs) derived cells reflect tissue specificity found in patients with Leigh syndrome French Canadian variant (LSFC).pdf by Roselle Gélinas (18408150)

“…Most LSFC patients in Quebec are homozygous for an A354V substitution that causes a decrease in the expression of the LRPPRC protein. …”

Mitochondrial mass is increased in <i>boss</i> mutant flies. by Ayako Kohyama-Koganeya (772758)

“…Data are means ± SEM (t-test, *P<0.05). (B) The amount of mitochondria was determined using Western blotting and anti-ATP5A antibody. …”

Induction of autophagy in converted fibers of the tgKO mice. by Shoichi Takikita (235435)

“…A markedly decreased phosphorylation of GSK-3β (on Ser⁹) is observed in muscle from KO and tgKO mice without a decrease in the amount of total GSK-3β. …”

Effect of alcohol abstinence on 4-HNE (×100). by Nobuhiko Hayashi (438001)

“…(B) Quantitative representation of the staining intensity of 4-HNE in A1−A6 stained sections. The data are mean ± S.D. of five liver samples (*<i>P</i><0.05).…”

Activating Hpo inhibits fat accumulation in <i>Drosophila melanogaster</i>. by Hongling Huang (404195)

“…<p>(a) Ectopic Hpo reduces larval body size and fat body reporter signal. …”

Table_2_Cladribine treatment specifically affects peripheral blood memory B cell clones and clonal expansion in multiple sclerosis patients.xlsx by Christoph Ruschil (9870365)

“…Ig peptides were overlapped with the corresponding IGH transcriptome in order to analyze B cell clones on a combined transcriptome and proteome level.</p>Results<p>The analysis of peripheral blood B cell percentages pointed towards a significant decrease of memory B cells and an increase of naive B cells following cladribine therapy. …”

DataSheet_1_Cladribine treatment specifically affects peripheral blood memory B cell clones and clonal expansion in multiple sclerosis patients.pdf by Christoph Ruschil (9870365)

“…Ig peptides were overlapped with the corresponding IGH transcriptome in order to analyze B cell clones on a combined transcriptome and proteome level.</p>Results<p>The analysis of peripheral blood B cell percentages pointed towards a significant decrease of memory B cells and an increase of naive B cells following cladribine therapy. …”

Table_1_Cladribine treatment specifically affects peripheral blood memory B cell clones and clonal expansion in multiple sclerosis patients.xlsx by Christoph Ruschil (9870365)

“…Ig peptides were overlapped with the corresponding IGH transcriptome in order to analyze B cell clones on a combined transcriptome and proteome level.</p>Results<p>The analysis of peripheral blood B cell percentages pointed towards a significant decrease of memory B cells and an increase of naive B cells following cladribine therapy. …”

Automated, high-throughput phenotyping. by Natasha Oswal (13889773)

“…Meanwhile, their apparent body size decreases until the time of death at which point it increases rapidly (green), plateaus, and then decreases again (gray). c. …”

<i>brummer</i> expression in males is necessary for maintaining male fertility. by Lianna W. Wat (8339454)

“…<p>(A) Males with whole-body loss of <i>brummer</i> have a significantly decreased number of progeny after 2 days, 4 days, and 6 days of mating (<i>p</i> = 2.2 × 10⁻¹⁶, 9.7 × 10⁻¹², and 4.6 × 10⁻⁶, respectively; Student <i>t</i> test at each time point). …”

Visualization of model structure. by Jason S. Prentice (213050)

“…(B) The mean spiking probability of each mode, <i>m</i>_<i>iα</i>, projected into two dimensions by multidimensional scaling (MDS). The color of each point indicates that mode’s log probability (as in A) while the size scales with the mode’s average population spike count, ⟨<i>k</i>⟩. …”

Peripheral Neutrophil Functions and Cell Signalling in Crohn`s Disease by Rajesh Somasundaram (499673)

“…<i>In toto</i>, these data show a disturbed signal transduction activation and functionality in peripheral blood PMN from patients with quiescent CD, which point toward an intrinsic defect in innate immunity in these patients. …”

Quantifying the timing of smooth eye movement planning. by Mazyar Fallah (322231)

“…Shading indicates the time points at which there was a significant deviation from the Standard condition. …”

Computational model: connectivity and simulations. by Tomas Knapen (33341)

“…The bottom figure that represents a traveling wave under the influence of a high level of stimulus motion has a ratio between clockwise and counter-clockwise inhibition width of 4∶1.…”

Data_Sheet_1_Mutation-driven evolution of antibacterial function in an ancestral antifungal scaffold: Significance for peptide engineering.docx by Jing Gu (390)

“…The latter folds into an amphipathic architecture stabilized by one disulfide bridge, which likely confers mehamycin a bacterial membrane permeability. Deletion of the sDBD remarkably decreased the ability but accompanying an increase in thermostability, indicative of a structure-function trade-off in the mehamycin evolution. …”

Data_Sheet_1_Riparian Vegetation and Sediment Supply Regulate the Morphodynamic Response of an Experimental Stream to Floods.docx by Anne F. Lightbody (6558233)

“…To advance mechanistic knowledge regarding these interactions, we measured the response of topography and flow to the presence of riparian tree seedlings with contrasting morphologies in an experimental, field-scale, meandering stream channel with a mobile sand bed. On a convex point bar, we installed seedlings of Tamarix spp. …”

Effector protein stability is linked to Mcsc function. by Kris E. Spaeth (259816)

“…(C–E) <i>Mcsc mutations in the putative effector binding domain disrupt cargo binding and destabilize Cap1 and Ct618</i>. (C). Point mutations in the putative effector binding regions of class I chaperones <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000579#ppat.1000579-Lilic1" target="_blank">[44]</a> were generated in the α1 (L15A) and β1 strand (L31, L33 & L35 to A or G) either in Y2H (D) or in <i>E. coli</i> expression vectors (E). …”

Supplementary Material for: Unstimulated Luteinizing Hormone for Assessment of Suppression During Treatment of Central Precocious Puberty with 6-Month Subcutaneous Leuprolide Aceta... by Klein K.O. (18450384)

Dendritic cells induce an IFN-I response during infection with <i>Histoplasma</i> yeasts. by Nancy Van Prooyen (2890961)

“…Yellow indicates an increase in gene expression relative to mock-infected samples, blue indicates a decrease, black indicates no change, and gray indicates missing data. …”

DataSheet_1_Phytoplankton spring succession pattern in the Yellow Sea surveyed at Socheongcho Ocean Research Station.docx by Myung Jin Hyun (17121016)

“…During early spring (late March to mid-April), phytoplankton biomass increased, accompanied by a decrease in nutrient levels, with Bacillariophyceae and Cryptophyceae being the dominant groups. …”