DNA–protein complexes generated by Cdc13 and CST. by Neal F. Lue (17075)

“…(B) The stability of the CST-DNA complex was estimated in a competition experiment. CST (10 nM) was allowed to form complexes with labeled CgTELX1 (7.5 nM) for 20 min. …”

Pharmacokinetics and pharmacodynamics after treatment of DIO-mice with HI, X10 and IGF-1 by sc injection. by Henning Hvid (486358)

“…Dotted line indicates mean blood glucose at time 0. Error bars; SEM. C: Plasma concentrations 0.5 h and >5 h after treatment with HI or X10, 600 nmol/kg. …”

Data_Sheet_1_Ototoxicity of polystyrene nanoplastics in mice, HEI-OC1 cells and zebrafish.DOCX by Yuancheng Wu (12012329)

“…Additionally, we found that exposure to polystyrene nanoplastics resulted in a significant elevation in the auditory brainstem response thresholds, a loss of auditory sensory hair cells, stereocilia degeneration and a decrease in expression of Claudin-5 and Occludin proteins at the blood-lymphatic barrier in mice. …”

Somatic Focus manipulated with incentivized discrimination tasks. by Natalie E. Johnston (318841)

“…There were no changes in temperatures calibrated to elicit moderate pain (level 5), so we could test the effects of expectancy and attention on a constant, moderate level of pain stimulation. …”

Alterations in ROS Activity and Lysosomal pH Account for Distinct Patterns of Macroautophagy in LINCL and JNCL Fibroblasts by José Manuel Vidal-Donet (280472)

“…Pulse-chase experiments show a significant decrease in protein degradation by macroautophagy in fibroblasts bearing TPP1 (CLN2) and CLN3p (CLN3) mutations. …”

Reperfusion Therapy Optimization in Acute Myocardial Infarction with ST-Segment Elevation using WhatsApp®-Based Telemedicine by Alessandra Batista Teixeira (12698707)

“…After implementing this network, there was a significant increase in the proportion of patients who received reperfusion therapy (60% vs. 92%), relative risk (RR): 1.594 [95% confidence interval (CI) 1.331 – 1.909], p < 0.0001 and decrease in the in-hospital mortality rate (13.4% vs. 5.6%), RR: 0.418 [95%CI 0.189 – 0.927], p = 0.028. …”

Impact of Protein Stability, Cellular Localization, and Abundance on Proteomic Detection of Tumor-Derived Proteins in Plasma by Qiaojun Fang (211668)

“…Quantitative comparison of large versus small tumors revealed that the abundance of proteins in plasma as measured by spectral count was associated with the tumor size, but the relationship was not one-to-one; a 3-fold decrease in tumor size resulted in a 16-fold decrease in protein abundance in plasma. …”

Trap density impacts trapping efficiency of Tryp-Chip. by Mariana De Niz (724286)

“…In the bottom-most row, D1: 63.5%, D2: 52.6%, and D3: 55.4%. This represents a 30% decrease in invaded traps between the top-most row, and the bottom-most row. …”

Diagram showing the effects of recombinant BMP-7 on alkaline phosphatase (ALP), lactate dehydrogenase (LDH), lactate and osteocalcin (OCN) (supernatant), combining the following fo... by Tim Schwarting (688396)

“…<p>Monoculture of pOBs without BMP stimulation served as a control (horizontal line).(A) Application of BMP-7 increased the levels of ALP activity, compared to those in the non-stimulated group. …”

Network Models of TEM β-Lactamase Mutations Coevolving under Antibiotic Selection Show Modular Structure and Anticipate Evolutionary Trajectories by Violeta Beleva Guthrie (204414)

“…<div><p>Understanding how novel functions evolve (genetic adaptation) is a critical goal of evolutionary biology. Among asexual organisms, genetic adaptation involves multiple mutations that frequently interact in a non-linear fashion (epistasis). …”

Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk by Jason De Melo (741261)

“…Elevation of <i>SIPL1</i> gene copy and mRNA is linked to a decrease in patient survival, especially for those with PR+, ER+, or HER2- breast cancers. …”

Table1_Sterilization of micronized indomethacin.DOCX by Karyna Krupianskaya (14337372)

“…Before and after sterilization, all samples were analyzed by high performance liquid chromatography with UV detection, whereby the assay of indomethacin was examined as well as the peak purity and the formation of impurities. In comparison to the non-micronized reference, both sterilization methods demonstrate a significant decrease of content of micronized samples and an increase of the impurity profile. …”

Improvements of Sound Localization Abilities by the Facial Ruff of the Barn Owl (<em>Tyto alba</em>) as Demonstrated by Virtual Ruff Removal by Laura Hausmann (257760)

“…The removal of the ruff resulted in a large decrease in elevational head-turning amplitudes.…”

Time-course imaging result of DCE-MRI and DW-MRI. by Xiaomeng Zhang (182897)

“…The mean values of normalized K^trans decreased 69% for TH-302 treated mice in Hs766t tumors, decreased 46% for Mia PaCa-2 tumors and increased 5% in SU.86.86 tumors. …”

Dose-Dependent Activation of Putative Oncogene <em>SBSN</em> by BORIS by Daria Gaykalova (153270)

“…In this work, we establish that <em>SBSN</em> is a novel non-CTA target of BORIS epigenetic regulation. …”

Characterisation of endothelial cell-specific AQP1 knockout mice. by Wei Zhang (405)

“…In contrast, sections from AQP1^fl/fl; Cdh5-Cre⁺ mice showed a nearly ~80.19% decrease in AQP1-labelled endothelial area compared to controls. …”

microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation by K. Dominik Conrad (280201)

“…Only miRNA duplex precursors of the correct length stimulate HCV translation, indicating that the duplex miR-122 precursors are unwound by a complex that measures their length. Insertions in the 5′-UTR between the miR-122 binding sites and the IRES only slightly decrease translation stimulation by miR-122. …”

Optimal duty factors and pair lag <i>vs</i> magnitude of force rate cost coefficient () at . by Delyle T. Polet (7907429)

“…Optimal duty factors in fore and hind remain close for all . Pair lag decreases slowly with force rate penalty. At no point do optimal duty factors and pair lags simultaneously match the empirical values (dotted lines) from [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007444#pcbi.1007444.ref037" target="_blank">37</a>]. …”

Biochemical/enzymatic assays, computational stability and dimerization affinity data. by Francesco Costacurta (19648605)

“…Inside the plot, a magnified subplot highlighting some data points. …”

Data Supplement from Epigenetic Targeting of Ovarian Cancer Stem Cells by Yinu Wang (14844702)

“…Low dose SGI-110 induces sustained cell cycle arrest on OC cells. A. Time-course cell cycle analysis of platinum sensitive A2780 ovarian cancer cells and platinum resistant A2780_CR5 and SKOV3 OC cells after 72 hour daily treatment with low dose SGI-110 (100nM). …”